Sun Mu

Nephrology||

[Sun Mu @NephBean]

@ChristosArgyrop You forgot bombing innocent civilians - mostly children

[Sun Mu @NephBean]

@kidney_boy You seem happy. Gaza's dead children in that box?

[Sun Mu @NephBean]

@dinukawrpt Classical Bartter syndrome patients are polyuric because of decreased urinary concentrating ability which is due to mTAL dysfunction and high prostaglandin production. Tolvaptan won't be helpful and it might theoretically worsen.
Tolvaptan itself causes polyuria and polydipsia.

[Sun Mu @NephBean]

@VelezNephHepato Is 2-6g/g doubtful because of deceased creatinine excretion?
Can you please elaborate. Thank you

[Sun Mu @NephBean]

@nephondemand @Ask_Renal Thank you sir for your kind response.

What should be the duration of treatment before labelling true resistant Hypertension?
Thank you

[Sun Mu @NephBean]

What should be the duration and dosage of antihypertensive medications when we label someone as resistant Hypertension?
@Ask_Renal #askrenal @hswapnil

[Sun Mu @NephBean]

@askrenal Better ask Chat-gpt.

[Sun Mu @NephBean]

What happens to Urinary NH4+ excretion in Proximal RTA?
@Ask_Renal @askrenal

What about this statement on uptodate?

[Sun Mu @NephBean]

@kidneydoc101 In retaliation Israel killed more than 10000 Palestinians with almost half being children. I won't ask you to do the math in terms of US or UK pmp. Every innocent human life is precious. You won't understand that because you are full of hatred. You are a disgrace 👎🏿👎🏿👎🏿👎🏿👎🏿👎🏿👎🏿

[Sun Mu @NephBean]

Do you use prophylactic calcium gluconate in plasma exchange by membrane plasma separation? If yes, then what's the protocol? #askrenal @Ask_Renal @ask

[Sun Mu @NephBean]

@kidney_boy Both AVP-D(CDI) and AVP-R(NDI) have been found with lithium therapy and polyuria in these patients shouldn't be presumed to be AVP-R.

[Sun Mu @NephBean]

#askrenal
@GlassockJ @roger

[Sun Mu @NephBean]

In a kidney biopsy with 15 glomeruli with 90% being globally sclerosed and 1 glomerulus showing segmental sclerosis, be labelled as global diffuse glomerulosclerosis or fsgs?

@DrGeetikaSingh1 @MPAlexanderMD @SethiRenalPath @draalok @renalpathdoc @DrRizwanRasheed @tiff

[Sun Mu @NephBean]

@manasib33 1. Selective glomerular hypofilration (shrunken pore syndrome)
2. Other causes that increase serum cystatin c or decrease creatinine.

measuredGFR may be more informative in this case than urinary creatinine clearance.

[Sun Mu @NephBean]

@RenalPathLabs ALECT2?

[Sun Mu @NephBean]

In a kidney biopsy with 15 glomeruli with 90% being globally sclerosed and 1 glomerulus showing segmental sclerosis, be labelled as global diffuse glomerulosclerosis or fsgs?

@DrGeetikaSingh1 @MPAlexanderMD @SethiRenalPath @draalok @renalpathdoc @DrRizwanRasheed @tiff

[Chris Larsen @renalpathdoc]

@DrGeetikaSingh1 @NephBean @MPAlexanderMD @SethiRenalPath @Richard @nephrosharma I usually only count as a percentage of intact glomeruli too. I think of this as a measure of activity and a globally sclerotic glomerulus cannot have an active crescent. As such, it does not make sense to me to use it in the denominator.

[Mercedes Noriega, MD @noriega_md]

@NephBean @MPAlexanderMD @SethiRenalPath @DrGeetikaSingh1 @renalpathdoc @Richard I also calculate from total Glomeruli. Important for the prognosis is how many Glomeruli remain healthy. I write in the Report how many are global +partial sclerosed and how many with newer lessions. Renal Score from Brix et al is really good. The ist an App for cell Phone

[Sun Mu @NephBean]

@DrGeetikaSingh1 IF negative makes early membranous unlikely.
Shouldn't matter what do we call it as long as the patient is treatment responsive (secondary causes should be ruled out)

[Sun Mu @NephBean]

@SethiRenalPath @DrGeetikaSingh1 @MPAlexanderMD @renalpathdoc @Richard @nephrosharma Thank you sir

[Sun Mu @NephBean]

In a kidney biopsy with crescents, is the percentage of crescents calculated from total number of sampled glomeruli or just the non-globally sclerosed glomeruli?

@MPAlexanderMD

@SethiRenalPath

@DrGeetikaSingh1
@renalpathdoc
@richard

[Sun Mu @NephBean]

@DrGeetikaSingh1 @MPAlexanderMD @SethiRenalPath @renalpathdoc @Richard @nephrosharma Thank you ma'am