Nicolas Doucet

Structural Biologist. Prof. at INRS-U. of Quebec (Montreal, QC). I study enzymes and I have 2 lovely daughters. Tweets are my own. He/Him/Il. @[email protected]

[Nicolas Doucet @nicdou]

New in #ProteinScience! @ProteinSociety🥳 We explored allosteric pathways in galectin-7, a key protein in high-fatality cancers. We identified dynamic nodes for functional modulation in #glycobiology.

Read: https://t.co/ho2HZLz3Cj

@GlycoNet @NSERC_CRSNG @FRQS1 @CanLightSource

[Nicolas Doucet @nicdou]

Entrevue à Point du Jour de @RadioCanada sur notre recherche à l’@inrsciences. Étude des ribonucléases, leur structure 3D et rôles biologiques.🔬👩🏻‍🔬 Grâce au @CanLightSource et au financement de @NSERC_CRSNG, @ProteoQuebec et @FRQS1. 🧬🧫 https://t.co/QGqNdIP0Qb
#enzymes #science

[Nicolas Doucet @nicdou]

Thank you to our colleagues from @UABBarcelona and @TrendsBiochem for this wonderful Spotlight article about our work published in @jbiolchem! 🧬🧑🏼‍🔬 #ASR #proteinengineering #biochemistry @inrsciences @Pratul_Agarwal @NSERC_CRSNG @FRQS1

[Trends in Biochemical Sciences @TrendsBiochem]

Available online - the Spotlight "Ancestral #ribonucleases back in motion for evolutionary-dynamics guided #proteindesign" from Ester Boix and Jiarui Li @UABBarcelona.

#moleculardynamics #ancestralsequencereconstruction #proteinevolution

Read it here 👉 https://t.co/SqR6uwjUB3

[Trends in Biochemical Sciences @TrendsBiochem]

Available online - the Spotlight "Ancestral #ribonucleases back in motion for evolutionary-dynamics guided #proteindesign" from Ester Boix and Jiarui Li @UABBarcelona.

#moleculardynamics #ancestralsequencereconstruction #proteinevolution

Read it here 👉 https://t.co/SqR6uwjUB3

[Nicolas Doucet @nicdou]

Thank you, @CanLightSource, for highlighting our article published in @jbiolchem! 🧬🧑🏼‍🔬 Researchers from @inrsciences are using the CLS to study how #enzymes can be modified to our advantage. #proteinengineering #biochemistry #ASR @Pratul_Agarwal

[CanadianLightSource @CanLightSource]

Researchers from @inrsciences are using the CLS to study how #enzymes found in all forms of life can be modified to work to our advantage - for everything from better cancer treatments to more efficient, enviro-friendly industrial catalysts. https://t.co/08alwhJAiN #health #dna

[Nicolas Doucet @nicdou]

Merci @CanLightSource pour la mise en valeur de notre article publié chez @jbiolchem ! 🧬🧑🏼‍🔬 « Des chercheurs de l'@inrsciences utilisent le CLS pour étudier comment les #enzymes peuvent être modifiées à notre avantage. » #proteinengineering #biochemistry #ASR @Pratul_Agarwal

[CanadianLightSource @CanLightSource]

Researchers from @inrsciences are using the CLS to study how #enzymes found in all forms of life can be modified to work to our advantage - for everything from better cancer treatments to more efficient, enviro-friendly industrial catalysts. https://t.co/08alwhJAiN #health #dna

[Nicolas Doucet @nicdou]

@ColleenBreitkr1 I think I just saw the same fire. 🔥 View from downtown #Edmonton

[Nicolas Doucet @nicdou]

Heureux et fier de participer à cette collection dédiée à l’ingénierie enzymatique éditée par @Chica_lab ! 🧬🧫🧑🏼‍🔬 Notre contribution est généreusement supportée par le @CRSNG_NSERC et le @FRQS1. #proteine #enzyme @inrsciences

[PEDS: Protein Engineering, Design & Selection @ProtEngDesSel]

Check out our latest special collection on #enzyme engineering! With contributions from @GreenGroupMIB, @IvanaDrienovska, @DavidKwanPhD, @ZhongyueY, Joelle Pelletier, @nicdou, Vincent Eijsink, Steve Mayo and others.
Free to read and download until September 30, 2023!

[Michael 英泉 Eisen @mbeisen]

I’ve learned from a decade on this app to not accept the superficial way things are presented here, especially when someone’s words are being used against them. And so I watched the whole session for context. And I’m glad I did. Because in context it’s way worse.

[FRQ - secteur Santé @FRQS1]

Bravo à l'équipe de @nicdou @inrsciences pour leur avancée dans la dynamique moléculaire chez les #enzymes! Une recherche appuyée par le @CRSNG_NSERC, les @NIH, la Fondation Armand-Frappier & le @FRQS1.
#communautéFRQ
@jrjulierobert @CongresAF
https://t.co/xf8wTS6m6c

[Structure @Structure_CP]

Team headed by N. Doucet @inrsciences & @Pratul_Agarwal reveals functional and evolutionary divergent features that govern conformational exchange within structurally homologous eosinophil ribonucleases @nicdou @tmhmpl @NSERC_CRSNG @FRQS1
https://t.co/zIBtH2jUUd

[Nicolas Doucet @nicdou]

#Budget2023 unfortunately means that graduate students will continue to live below the poverty line in Canada! 🇨🇦 Sad. 🤦🏼‍♂️😢 @cafreeland @justintrudeau #SupportOurScience @SupportOurSci @FP_Champagne @CIHR_IRSC @NSERC_CRSNG #ISupportGradStudents #ISupportPostdocs @inrsciences

[Trushar Patel, PhD, DSc 🇮🇳🇨🇦 @trushar_7]

The 8th annual meeting of the Biophysical Society of Canada @BiophysCanada will be held at @UCalgary from May 23rd to 26th.

Abstracts are due on April 15th.

For information on a list of speakers and other details, visit
https://t.co/Xd6FRIpLY0

Please RT and spread info.

[Nicolas Doucet @nicdou]

Prolongation de la période de mise en candidature du poste d’agent.e de #recherche en #biophysique à @inrsciences. Soumettez votre candidature d’ici au 6 mars 2023 et/ou partagez parmi vos contacts et vos réseaux ! 🧪🧬👩🏽‍🔬 https://t.co/zIO0xuwGFg

[Nicolas Doucet @nicdou]

J’ai écrit ça sur le coup de l’émotion,💔 mais c’est un peu le ras-le-bol face à la démission de notre @GouvQc. @LeFredSavard, merci d’être l’un des seuls qui en parle encore. Désormais, la tristesse en ressort bien davantage que la colère.😢 Merci @LeDevoir d’avoir publié.🌹

[Le Devoir @LeDevoir]

Au-delà des larmes https://t.co/sfnjb0uchj

[Buitengebieden @buitengebieden]

Bunny eating strawberries.. 😋 https://t.co/dfFdIm6cra

[Mathieu Ferron @Mathieu_Ferron]

Quand même le Journal de Montréal écrit un article sur le sous financement de la recherche... c'est qu'il y a vraiment un problème. @FP_Champagne @JustinTrudeau : il est temps de réinvestir dans le financement de la recherche au Canada.

https://t.co/R98LZdqn7l

[Nicolas Doucet @nicdou]

We believe the next frontier in #enzyme engineering is to exploit their #dynamics. Always a pleasure to work with #JoellePelletier and @claudele_ from @UMontreal! 👩🏻‍🔬🧬👩🏽‍🔬🧪 Thanks to our funding partners and RIP #DanTawfik.😢 @CRSNG_NSERC @FRQS1 @inrsciences @SciChefQC @SciChefCan

[Claudèle Lemay-St-Denis @claudele_]

With @nicdou and #JoellePelletier, we recently reviewed the state of knowledge in ‘dynamic engineering’, i.e. the rational modification of #protein dynamics to alter #enzyme function! https://t.co/bX25QD6DWG
#ProteinEngineering

@ProtEngDesSel @NSERC_CRSNG @inrsciences @UMontreal