🔥 A simple nasal spray may one day reverse brain ageing by switching off chronic neuroinflammation.
➡️ A new study shows a non-invasive nasal spray can reduce age-related brain inflammation (“neuroinflammaging”) and improve memory.
➡️ The therapy uses extracellular vesicles carrying microRNAs, which reach the brain directly via the nasal route and modulate inflammatory pathways.
➡️ It restores mitochondrial function and cognitive performance, with effects seen within weeks and lasting months in animal models.
➡️ This suggests brain ageing may be reversible, though human studies are still needed.
https://t.co/lfq2HNCJDO
@sunsopeningband Points to same problem -> the system doesn’t give time to clinicians to gather better data. Limited time for physical exam.
Insurance eliminated care delivery for profits
I'm fascinated by Urolithin A.
It's a compound that stimulates mitophagy (mitochondrial autophagy), helping clear out and replace damaged or dysfunctional mitochondria.
Recent studies show that urolithin A improves endurance performance and even keeps immune cells "younger" with age.
The data are early and emerging, but promising enough that I've started to supplement with it, as I discussed with @hubermanlab when I appeared on his podcast recently.
We've seen the Shingles vaccine is linked with reduced risk of Alzheimer's and dementias in 4 large natural experiments.
Today, the potential of high-dose flu vaccines vs standard dose for the same in a large retrospective age 65+ cohort [N>160,000). More pronounced in women (like Shingles vaccine)
https://t.co/dxYzURf7QH
This is what happens when passionate clinicians dig deep to help patients. If healthcare was run more this way, we’d have more clinicians being able to help their patients. Sick care increases in 10 min visits.
I respectfully disagree. As a general pediatrician caring for a large neurodiverse population (ASD, ADHD, dyslexia, CAPD, concussion, anxiety), I’m seeing a very different reality over the last 5 years. 🧵1/14
@nwagoner Maybe this has more to do with your injuries vs the electrical field theory. Not having adequate training staff+facilties to attend to all players could be a major void, especially if they’re behind other teams. Good to hear Lynch addressing it. #49ers let’s get 🏆 in 2026!!
Ok all the kids/adults wearing one #AirPod in an ear are doing serious #neyroplasticity harm. Auditory -spatial processing is being impaired. Don’t be surprised if you get startled easily @socrdoc I’m starting to look at this more in my patients
#youth#clubsports is a business understand that. That’s why year round play is important. But may not be best for the youth athlete and science supports it #LTAD
A massive new study on peak performance included 34,000 international top performers: Nobel laureates, renowned classical music composers, Olympic champs, and the world’s best chess players. It shows early specialization is a trap, and the road to greatness is long and varied.
@MVGutierrezMD@DPT2Go Yup we’re on that our tech is in deployment for EPIC users, more to come. Let’s get #concussion#ppcs#pcs survivors and the providers data to help them recover efficiently https://t.co/Ui90upGMCF
Here comes a real test in beliefs vs science. Do you want to risk #shingles#dementia or take a #vaccine I lost a parent to dementia wasn’t an enjoyable process. You can ask other family members their experience I’m sure they’ll say the same 💉
https://t.co/uRfn3M1T2d
@SaitAshina@JCephalalgia Agree. Neuromuscular activation alterations further impact symptom persistence. Look forward to more anti-cgrp regiments. Be mindful, TMD has many other pathways causing facial pain referral that may not be migraine.
@AutonomicBrad Unfortunate another syndrome/condition that tears families apart. Seen it first hand the strains families and the patient go through. Stay strong together
When a child with a brain injury begins the transition to adulthood, certain challenges can arise. In a recorded BIAA webinar, we discuss these challenges and give tips for caregivers to navigate this period of their child's life. Watch the recording here: https://t.co/oxdY17Ggcg
@sunsopeningband All medical AI experts an groups including the leaders like #AImed say clinicians who use it will make them more efficient. It’s not replacing clinicians