Nik Machairas

Assistant Professor @UOAofficial
MD, PhD, FACS
HPB Surgery / Liver Transplant / 🧬🦀🔪
@UOAofficial x @RoyalFreeNHS x @MayoClinic

[E-AHPBA @EAHPBA]

🙌BRAND NEW 🙌
Explore the future of HPB surgical education with the E-AHPBA Online Academy — expert-led webinars, interactive modules & global collaboration to advance your practice.

Read more - https://t.co/iG7yqvatZJ

[Giovanni Marchegiani @Gio_Marchegiani]

🧬 RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

🎯 A milestone one in @Nature 🎯

🦠 Responders with vaccine induced t-cells have prolonged RFS compared to non responders

💉 Vaccine for PDAC not a dream anymore?!

https://t.co/yXsOhtqBwj

[Diamantis I. Tsilimigras, MD, PhD, MS @DTsilimigras]

Check out our latest study on #Racial and #sex-based variations in #genomic profiling of #iCCA published in @AnnSurgOncol @SocSurgOnc

Different genetic drivers that may be targetable to treat diverse cohorts @OhioStateSurg @timpawlik @johnntanasis

https://t.co/7KvM0rcate

[Nik Machairas @nmachair]

@Gio_Marchegiani @BjsOpen @villesallinen @Mcfark @LauraLorenzonMD @BJSurgery @des_winter @JJEarnshaw @ksoreide @young_bjs @MalinASund Well, some journals read the signs some insist not to

[Nik Machairas @nmachair]

@Totuccio1983 @Gio_Marchegiani @MauroPodda2 @BjsOpen @villesallinen @des_winter @BJSAcademy @young_bjs @juliomayol @JBMatthews @ksoreide @WHO @heatherevansmd Fully agree 🔝

[Salvatore Paiella @Totuccio1983]

@Gio_Marchegiani @MauroPodda2 @BjsOpen @villesallinen @des_winter @BJSAcademy @nmachair @young_bjs @juliomayol @JBMatthews @ksoreide Pip/Tazo is in the @WHO Watch category of the AWaRe classification and it should not be used deliberately! It’s a lazy way of treating SSI. More appropriate to tailor the treatment based on bile stenting, preop bile culture, and rectal swab colonization with MDR! @heatherevansmd

[Giovanni Marchegiani @Gio_Marchegiani]

Antibiotics 💊 for prophylaxis during pancreatoduodenectomy 🙋🏻‍♀️ … did you change your practice?

💉 Pip/Tazobactam ⬇️ surgical site infections and major complications

New meta-analysis supporting 🇺🇸 trials just published!

👉https://t.co/n13OXzk5PB

[Jayant Kumar (he/him/his) @JayKumar_MD_PhD]

We express our sincere gratitude
for your attention and interest in our recently published study @BjsOpen titled "Piperacillin/tazobactam for surgical prophylaxis during pancreatoduodenectomy: a meta-analysis ." We are hopeful that the findings from this study will contribute towards enhancing the outcomes of the whipple procedure. @hollylneville @mhshospital

@imperialcollege @UChicago @uchicagosurgery @cuttingman_fung @MauroPodda2 @nmachair @RArasaradnam @FraVirdis

[Marcello Di Martino @MarcDiMartino]

First paper from Novara @UniAvogadro

Data from #MANCTRA-1 highlight the relevance of
➡  Socioeconomic inequity by HDI (local factors)
➡ Adherence to clinical guidelines (local protocol)
on
🔥 Clinical outcomes

Massive 🙏to promoters & collaborators!

https://t.co/SHq61Vssmu

[Giovanni Marchegiani @Gio_Marchegiani]

💫 Building the next gen of HPB Surgeons ✨

Read about the new @EAHPBA programs

👩‍🎓 Early Career Group
🖥️ Online Academy
🧙‍♂️ Mentorship Program and... fellowships!

The future is (finally) already here!

👉https://t.co/cjBoeS0Kpq

[Pancreas Verona @PancreasVerona]

Tribute to Claudio Bassi by our chairman @SalviaRobi at the @IHPBA meeting in Cape Town. Claudio truly believed in young generations and created a training system for pancreatic surgery that is still unique natuonwide. We prouldy carry your legacy on ❤️😷 @EAHPBA @AHPBA @APHPBA

[Pancreas Verona @PancreasVerona]

🚨PANDORINA, a binational 🇳🇱🇮🇹RCT of drain 🆚 no drain in distal pancreatectomy out in @LancetGastroHep !
✅Major morbidity 20% vs 15%
✅POPF 27% vs 12%
➡️A no-drain policy is safe and reduced POPF and should be the new standard approach
@DPCG_official https://t.co/Y5Wu8wahDY

[Nik Machairas @nmachair]

📣 Check out our latest review article published in @jogs, focusing on state-of-the-art in simultaneous resection for colorectal cancer with synchronous liver metastases

➡️ https://t.co/K2iLYEpj4l

@timpawlik @MarcDiMartino @FPrimavesi @DTsilimigras @Adam_Frampton1

[Salvatore Paiella @Totuccio1983]

Out now! How many patients fail to access adjuvant therapy after surgery for resectable #PancreaticCancer?25%🥧! Why?(Data from 317 pts)
1) 🩹Postop compl
2) 🧑‍⚕️Oncologist's choice
3) 💊Comorbidities
Less likely:
- 👵Elderly
- 💧POPF
@PancreasVerona @EAHPBA @IHPBA @AnnSurgOncol

[Syed A. Ahmad @SyedAAhmad5]

Laparoscopic Liver Tunnel for Tumors at the Hepatocaval Confluence ⁦@AnnSurgOncol⁩ https://t.co/yucVOoV2H6

[Nik Machairas @nmachair]

👉 In https://t.co/ZH8dQJtJBB 2 we now seek to investigate aspects contributing to FTR on a hospital and institutional level, across various Human Development Index countries, aiming to further improve patient care and safety in pancreatic surgery 🌏🌍🌎

[PancreasGroup.org @PancreasGroup]

🚨https://t.co/ogKjVuJEID 2
💡Survey on Hospital Factors Affecting Failure to Rescue in Pancreatic Surgery

Participate now!
👉https://t.co/wYFpvyqMut

✅ Complete the online Survey ⏰10min
✅ Stay anonymous
✅ No need for ethics approval
✅ PubMed citable co-authorship

[Giovanni Marchegiani @Gio_Marchegiani]

🎁 It's that time of the year...

🎄 Best of Pancreas Wrapped 2023!!! 🍾

1⃣ January 2023: Pancreatic cysts when to stop surveillance !? 👇👇👇

[Pancreas Verona @PancreasVerona]

What is the difference between long-term survival and cure following pancreatectomy for PDAC? Check this out: Cure Probabilities After Resection Of Pancreatic Ductal... : Annals of Surgery https://t.co/DLoU67eaGw @StefanoCrippa6 @gimalleo @cuccoale @Aicep4 @AISP_Pancreas

[Thomas Stoop @TFStoop]

Today in @NatRevGastroHep, review BRPC-LAPC #PancreaticCancer

📌 Preoperative chemotherapy & radiation
📌 A-B-C (re)staging & surgical decision-making
📌Clinical research agenda

Great team effort 🇩🇪🇺🇸🇳🇱 https://t.co/220O76dUHp

[Nik Machairas @nmachair]

Outcomes from the @PancreasGroup are now publsihed in @BJSurgery !

🚨Get ready for PancreasGroup 2, coming soon!

https://t.co/UsV5B8WjNB

[Giovanni Marchegiani @Gio_Marchegiani]

Today a great @BJSurgery meeting and tomorrow is the World Pancreatic Cancer day 💜

😢 Pancreas surgery still associated to poor outcomes worldwide

🌍 In low human development index countries 🔺failure to rescue

🛟 Urgent measures needed!

🆓 access! https://t.co/mOWzT2nmDp