At last, in print sans "pre-"! Grazie mille to my co-authors/co-conspirators @jcslab at beyond, w/o whom I'd still be stuck on a translation problem! TL;DR: Mtb codon context bias may be baked in to regulate transcription, but I hope you'll give it a read. https://t.co/8kmI7J6SV9
FINALLY! Thanks to the indomitable @JaisinghaniN87 we proudly present the ultimate Mtb cell wall proteome and some surprising-- and exciting-- members: Type VII secretion substrates EsxB & EsxG! 1/n https://t.co/iT5gnChqfd
Infinite thanks to @jcslab and the many brilliant/generous collaborators who made this science adventure possible! ✨💕🥲 And thanks, of course, to mycobacteria for being such interesting weirdos.
Hurrah! Announcing the awesome thesis work of @noosly!
Or, how synonymously recoding genes in mycobacteria is like Bjork’s “It’s Oh So Quiet”. 1/n https://t.co/DuK4l0Zd5u
Hurrah! Announcing the awesome thesis work of @noosly!
Or, how synonymously recoding genes in mycobacteria is like Bjork’s “It’s Oh So Quiet”. 1/n https://t.co/DuK4l0Zd5u
Being done doesn't feel like being done when you've got unfinished manuscript business. But this is a good time as any to say I've had (am still having??) the best time in the best lab @jcslab
@pmoyniha Reminds me of this paper. Could there be a relationship to ribosome stalling/mRNA conformation change at certain codon pairs? https://t.co/efG9DQ4o3I
Check out our, @GeneWeiLiLab @julianstanley_, new paper showing that a large fraction of RNA molecules in bacteria are fragments of canonical full-length mRNAs with consequences for differential RNA-seq analysis: https://t.co/esNmOMljXu
Synonymous sequence changes are not necessarily silent, and here they can have life-or-death consequences.
Now out in @eLife by former lab members @JIPerlmutter and Jane Meyers. Thanks to editors and reviewers for the constructive and kind review.
https://t.co/vdiHEQrl5F
Happy to have penned this review on bacterial lipidomics with @JaisinghaniN87! All reviews co-edited with @basktastic for this #lipidtime issue coming soon....
Free access to our paper: https://t.co/RpBulf3L1F
🚨I wrote a big piece about how Delta affects the pandemic endgame.
Many folks are upset & confused by the last month. Here's an attempt to reset expectations, lay out our goals, map the near-term future, & show how the pandemic ends--which it will. 1/
https://t.co/4Ukv7zs91X
JSeeliger Lab is hiring a postdoc! See official ad below and please help spread the word.
Wanted: #microbiology /#biochemistry/chem bio experience and eagerness to explore all things mycobacteria w/ a focus on the cell envelope.
Excited for @BBM today and tomorrow! For fun in mycobacteria visit @jcslab 5-min poster talks:
#47 @noolsy - unexpected consequences of gene recoding on expression
#58 @LiaParkin - exploring lipid transport functions of a membrane transporter and lipoprotein
Excited to share our first preprint on inhibitors of M. tuberculosis that we characterized using a competitive activity-based protein profiling platform. A long-haul team effort from @jcslab@AldridgeLab@canaanlab and the Cravatt lab. 1/n