Humbled to share that I've been awarded the ERC Starting Grant! This opportunity will help me develop strategies to bypass chemotherapy toxicity in blood stem cell transplantation. Grateful for the support of my mentors, family, and institutions. Excited to make a difference !🚀
Our work has been published in @Cancer_Cell
Thanks everyone!
@SanRaffaeleMI@AIRC_it#GeneTherapy#Immunotherapy
In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases: Cancer Cell https://t.co/FQDwR9utLt
We experienced in the last years the power of lipid #nanoparticles for RNA #vaccines and liver #editing. Now it’s time for ex vivo LNP-based T cell and #HSC#CRISPR editing!
Take a look to our last effort just published in @BloodJournal!
@NaldiniLab
https://t.co/1G9p9GkyM5
Today in Journal of Lab Satisfactions we describe our latest effort in trashing thousands of DNA samples from the two latest publications by Aurélien and myself, building us in 1:1 scale with the empty boxes!
Kudos to @fiumara_martina and @NaldiniLab!
Thanks to @danielevanbauer for the accurate and insightful commentary on our recent publication in @CellStemCell. We strongly advise reading it to get a fair overview on the potential implications of our work.
@Orelou3 @NaldiniLab
https://t.co/GXswbTemVY
Out in @CellStemCell our Article on #geneediting and #CRISPR in human hematopoietic #stem cells (HSC), comprehensively investigating the detrimental mechanisms of #AAV toxicity and reporting solutions to improve editing. 🧵 below! @NaldiniLab 1/n https://t.co/KxFzK4kqXr
Fully funded #PhD positions available in Naldini’s lab in the field of #genetherapy, at Università Vita-Salute San Raffaele (Milano, Italy).
Apply now to work in a center of excellence!
Deadline: August 1st
https://t.co/o9BucYuMa5
Our paper is finally OUT on @ScienceTM!🔥
🔴Inducible HSC-based gene therapy platform for tumor-targeted delivery of pro-inflammatory cytokines (IFN-α and IL-12)
🔴Inhibition of GBM growth and prolonged survival
🔴GBM TME reprogramming (by scRNA seq)
https://t.co/XxlPVFzRF4
A dream come true!
Thrilled to be presenting today at #ISSCR2022. Join me at 1:35PST, track clinical applications, if you want to find out more about ways to improve gene therapy. @Telethonitalia @SanRaffaeleMI
Un nuovo protocollo di #TerapiaGenica che sfrutta la tecnologia #mRNA.
Lo studio, realizzato dall'SR-Tiget @SanRaffaeleMI @Telethonitalia, per evitare gli effetti tossici della chemioterapia.
https://t.co/x4AQITk0x8
Extremely honored for being awarded an @EHA_Hematology#Research#Grant! It is an immense plaesure for me to join the EHA community and I am thrilled to start this new #adventure!
Thank you to all the people that made it possible and that supported me during these years.
How to bypass chemotherapy in the context of hematopoietic #stemcells#CRISPR#GeneTherapy? Find out now in our recent paper @CellCellPress. Could not have done it without kick-ass colleagues @GabriPedrazzani @NaldiniLab and supportive institutions @SanRaffaeleMI @Telethonitalia
I failed you on so many level Pakistan,
But you did not let me down Pakistan,
Today, you gave me hope Pakistan,
Today, you made me proud Pakistan,
#NayaPakistanMubarak#AaAbLautChale