The Yewdell Lab @genentech is seeking a summer intern for 2026!! An excellent opportunity to learn how we combine fundamental, basic research with drug discovery to create novel therapeutics, and to see what biotech is all about. Apply now! https://t.co/NPF0WZOpMW
Summer 2026 internship @genentech! Join us in South San Francisco to help advance cancer treatments through computational biology. MS and PhD students welcome
https://t.co/WpPdVqN9eT
TCR repertoire dream: decoding immune status by sequencing TCRs. Problems: 1) Need paired TCRab chains 2) Interesting T cell clones are often VERY small. Our solution: TIRTL-seq 🐢Deep, quantitative, & affordable paired TCR repertoire sequencing. 🧵 https://t.co/n90d3DLZHV (1/11)
Mechanistic framework of how antibodies can optimize protective immunity, regulating B cell response participation and duration in a way that can be harnessed for vaccine design @ImmunityCP @isaak_quast
https://t.co/DA8VPZdQ5q
In new preprint we delve into early memory B cells which are the frontline in generating antibodies against a familiar threat. We found that after first COVID vaccination a lot of pre-existing memory rapidly makes antibody-secreting cells despite weak binding to the viral protein
Like others have shown, many pre-existing memory B cells against SARS-CoV-2 don't recognize common cold coronaviruses – the main suspect for triggering the generation of these cells
@Arien_Schiepers@biorxivpreprint Beautiful experiments! What do you think about why antibody feedback doesn't stop MBCs from generating PBs after boost?