Wheels

learner

[Wheels @obscuresparrow]

I hoped @bryan_johnson that you would respond to your AIG like this. love it. nothing ventured nothing gained.

[Bryan Johnson @bryan_johnson]

My plan to cure autoimmune gastritis

To our knowledge, no one has ever done this to try and cure an autoimmune disease.

Context: In May, I got diagnosed with autoimmune gastritis (AIG). We found it by taking a tissue biopsy of my stomach. My immune cells are confused, causing my stomach to eat itself.

AIG stops your body from absorbing nutrients like iron and B12, and can eventually lead to cancer. It likely started decades ago when I was diagnosed with hypothyroidism when 21 years old. The thyroid and stomach are closely linked in your immune system.

I feel fortunate that I've been taking such good care of my body for the past five years as my condition would otherwise be much more severe. Millions of people are affected by this disease and are undiagnosed.

Standard of care tells you that you can’t do anything about it. That’s old fashioned.

Here is how we are going to try and cure it:

Step 0: find and diagnose the disease ✅

AIG is rarely caught early because symptoms are subtle. Early warnings are low iron and B12, but when hemoglobin and hematocrit look normal, doctors routinely miss it because there are no obvious signs of anemia.

A standard colonoscopy won't find it either, because it only checks the lower digestive tract, not the stomach. It was only through a highly targeted stomach biopsy that we found it. Even biopsies can miss it if they don't sample the exact right spots. Most people with AIG go undiagnosed.

Step 1: Map my immune system ✅

Last Thursday, I had a blood draw to isolate and decode 1 million of my immune cells. Think of your immune cells as trillions of soldiers. Each carries a unique key designed to unlock and destroy a specific threat, like a virus or bacteria.

A standard blood test allows you to see how many soldiers you have, but not their keys. Sequencing one million individual immune cells allows us to read the exact pattern of the teeth on every single key.

This is important for my autoimmune gastritis (AIG) because a specific platoon of rogue soldiers has developed keys that unlock an attack on my stomach lining.

Right now, we don’t know who they are. This test will inform us of which soldiers have gone rogue and are attacking me from within.

Once we know the soldier and key, we know what therapy path to pursue to shut them down.

Step 2: Catch the rogue soldiers

I will be getting a second biopsy from my stomach because we need to collect live tissue. We are currently planning out the logistics of getting the sample from my stomach to the lab.

We need these live cells because the initial blood tests showed the antibodies, which prove that an attack is happening, but doesn’t show us the actual rogue soldier doing the damage which is a T-cell.

The live sample will allow us to match the immune system mapping we did to the live T-cells.

Step 3: Build an early warning system

To keep an eye on the disease as we work towards a therapy, we’re building an early warning system. I'll have my blood drawn every two weeks and we’ll pair that information with wearable data to look for flare ups. This is important because the attack happens without producing symptoms that I can easily feel.

Step 4: Create a “Bryan in a dish” testing model, a miniature of my immune system

At the same time, we are taking a massive sample of my immune cells and deep freezing them (cryopreservation) for two reasons:

a) we’ll create a living lab: using these cells to replicate my immune environment in a lab dish. This allows us to test experimental drugs and therapies on my actual live cells before putting them into my body.

b) it creates a back up plan for me by preserving the raw cellular material needed for targeted rejuvenation therapies in the future.

Step 5: Build precision guided therapies to end the attack

Once we know who the rogue soldiers are, we will engineer a therapy designed uniquely for them. The trick is only turning off the rogue soldiers while leaving all the other healthy ones functioning as they are.

For safety checks, we’ll do two test runs:

1) we’ll run the therapy through a computer model that has my biology to evaluate how my molecules interact.

2) We will take my actual cells that we froze in Step 4 and watch them interact for real.

If both are successful, we’ll pursue one of four therapies:

a) fix the mistake my cells are making, restoring my immune system's natural off switches

b) teach the rogue cells to tolerate my stomach instead of attacking it

c) design smart molecules that physically plug into the rogue cells and turn them off

d) build soldiers who will track down and eliminate the rogue soldiers causing the damage

[Token Terminal 📊 @tokenterminal]

https://t.co/45EWmHDOcd

[Wheels @obscuresparrow]

I think @wmougayar is right. @ethereum is brilliant and has a strong moat but now it needs product managers to tell the world and users how they can use Ethereum to solve a problem for users

[William Mougayar @wmougayar]

https://t.co/8OfiTMYLeC

[Kabuki🔴 @kabukistory]

Bitcoin has done this twice already.

2017 ATH broke. Panic. Then 3x.
2021 ATH broke. Panic. Then 2x.
2025 ATH broke again. Panic NOW.

The fakeout is not the end. It's the entry.

Don't let them shake you out again.

Follow me I'll call all the moves live.

[Bitcoin Magazine @BitcoinMagazine]

JUST IN: 🇺🇸 Four-star military officer Admiral Samuel Paparo confirms the USA is running a Bitcoin node.

"We have a node on the Bitcoin network right now. We're doing a number of operational tests to secure and protect networks using the Bitcoin protocol."

[𝙲𝚘𝚕𝚒𝚗 𝚃𝚊𝚕𝚔𝚜 𝙲𝚛𝚢𝚙𝚝𝚘 @ColinTCrypto]

$BTC tops sharply and bottoms slowly-- the opposite of stocks, which bottom sharply and top slowly.

There's no rush to buy the bottom like some might make you believe.

Bitcoin bear markets tend to take a long time to consolidate at the bottom ranges. This is what kills people-- the apathy of low prices combined with the extended duration.

This is where you get statements of BTC's "death" every cycle.

https://t.co/lkbG3bM7C5

[Ed Conway @EdConwaySky]

🎥WHO PLACED THE BET?
Someone just made a killing with an extraordinarily well-timed bet on financial markets, minutes before Donald Trump's announcement of war talks yesterday.
Was it luck, or inside information?
Either way... someone just got rich.
Four min primer👇

[Wheels @obscuresparrow]

@AlexFinn I will have a conversation about your actions and intentions with @grok.

[Boring_Business @BoringBiz_]

This is probably one of my favorite clips from Stanley Druckenmiller. Listen to it at the start of every new year

"We have always believed that January 1 is when the house starts. I think this is the reason we have not had a down year. When I am up, I will play much more aggressively.

I see a lot of managers get up 20% and say I want to book my year, I made my high watermark, lets go to the beach. I am the opposite. Frankly I learned a lot of that from George [Soros]. If you are up 20 or 30%, you are playing the house money, thats when you try to get up 60 or 70%."

[Abdul @0x_Abdul]

If you ever feel cynical about crypto and it's future, watch this video

He literally explains why crypto matters and why we're all here:

[sysls @systematicls]

https://t.co/FQe5bCBqW1

[Eli5DeFi @Eli5defi]

https://t.co/mFYmOfWSQE

[Wheels @obscuresparrow]

if #Crypto market is moving to away from meme economy back to fundamental products, i'm keeping a close eye on @aave.

[Stani @StaniKulechov]

https://t.co/s1ozjoYDyX

[Wheels @obscuresparrow]

a good sobering read during this downturn #CryptoScam #CryptoCommunity #bitcoin

[nic carter @nic_carter]

https://t.co/j7OZyqsTcx

[Wheels @obscuresparrow]

Need more posts like this to up my AI video
#AI #Grok

[tetsuo @tetsuoai]

🎨 The Grok Imagine Prompting Cheat Sheet

Stop letting AI guess your camera angles.

Most people prompt "Cool cyberpunk character" and get the same boring medium shot every time. To get cinematic results, like the shots in the video below, you need to speak the director's language.

I broke down the specific Shot Types into a copy-paste formula for Grok.

⚠️ Pay attention to the "Mistake" section at the bottom, it solves the two most annoying AI habits.

Steal the cheat sheet below. 👇

Formula: (Shot Type) + (Art Style) + (Character) + (Clothing) + (Style Details)

1. 📐 Shot Type (The Frame)

• Establishing Shot: Far away, environment focus.

⚠️ PRO TIP: If the AI zooms in too close, describe your character as a "tiny silhouette" to force the camera back.

• Full Shot: Head to toe. Best for showing off outfits.

⚠️ PRO TIP: If it cuts off the legs (landscape mode), describe the boots and the floor to force the full frame.

• Medium Shot: Waist up. The standard "dialogue" shot.
• Close-Up: Head and shoulders. Focuses on emotion.
• Extreme Close-Up: Macro focus on a specific detail (eye, ring, scar).

2. 🎨 Art Style

• 90s Anime Cel-Shaded
• Cinematic 35mm Film Photography
• Digital Concept Art (Unreal Engine 5)
• Dark Fantasy Oil Painting

3. 👤 Character

• Cybernetic Street Samurai
• High-Elf Diplomat
• Noir Detective

4. 🧥 Clothing

• Holographic flight jacket
• Tattered ceremonial robes
• Tactical ballistic vest

5. ✨ Extra Style Details

• Volumetric fog & God rays
• Golden Hour lighting
• Film grain

📋 Copy-Paste Examples

• The Scene Setter (Establishing Shot): "Extreme wide establishing shot of a massive fantasy metropolis built into a cliffside. In the distance, a tiny silhouette of a traveler stands on a bridge. Cinematic lighting, epic scale."

• The Outfit Showcase (Full Shot): "Full shot of a 90s Anime style Mech Pilot wearing an orange flight suit and heavy magnetic boots, standing on the concrete hangar floor. Cel-shaded details, industrial lighting."

• The Emotion (Close-Up): "Close-up of a Hyper-realistic Soldier, intense stare, mud splatters on face, 8k resolution, dramatic shadows."

🛑 Troubleshooting: Common Mistakes & Fixes

Mistake #1: The "Vanity" Zoom (Establishing Shot)

❌ Bad Prompt: "Establishing shot of a Cyberpunk hacker wearing a black trench coat with blue neon circuit patterns, high collar, and tactical gear."

Why it fails: You described the clothing details too much. The AI panicked and zoomed in to show you the "neon patterns," ignoring your request for a wide shot.

✅ The Fix: "Extreme wide establishing shot of a massive Cyberpunk city. In the distance, a tiny silhouette of a hacker stands on a rooftop." (Describe the environment, not the clothes).

Mistake #2: The "Missing Legs" (Full Shot)

❌ Bad Prompt: "Full shot of an anime pilot standing in a hangar."

Why it fails: In landscape images, AI hates leaving empty space on the sides. It naturally zooms in to the waist (Cowboy Shot) to fill the frame, cutting off the feet.

✅ The Fix: "Full shot of an anime pilot wearing heavy magnetic boots, standing on the concrete hangar floor." (Describe the footwear and the ground to force the AI to render the bottom of the image).

[Wheels @obscuresparrow]

Truth is hard to accept but good for the $-bag. Great post #CryptoMarket #btc

[Santiago R Santos @santiagoroel]

Reading the replies to my post only makes me more certain: we’re deep in the Complacency phase of the cycle. And yes - we can go much lower.

I still haven’t seen a credible argument for why crypto networks - Ethereum, Solana, Ripple, etc. - deserve their current valuations.

These networks have utility. But utility ≠ value capture.

“Institutional adoption” isn’t a valuation model. It definitely doesn’t justify tokens trading at 50x+ P/S.

Meanwhile, the strongest AI + infra companies - actual revenue, actual unit economics - trade at 8–12x EV/revenue… and their revenue doesn’t evaporate in down cycles.

Crypto is still priced like a religion, not a business. Complacency.

[Wheels @obscuresparrow]

Great Article @jarrodwatts, I hope ERC – 8021 passes. #Ethereum will have a chance at longevity if it continues to adopt innovation.

[Jarrod Watts @jarrodwatts]

https://t.co/PmoNiuJFXC

[Wheels @obscuresparrow]

#btc #MarketUpdate #CryptoMarket #CryptoETF

[Rowshan @rowshanchannel]

🪶 X-Post Caption

🟨 Market Pulse — 30 Oct 2025
BTC $109 860 (–0.7 %) • ETH $3 844 (–2.2 %)
RSI rising • Funding flat • Skew easing • ETF outflows cooling heat

Market catching its breath after a strong run.
Quiet accumulation 👇

[Wheels @obscuresparrow]

#CryptoMarket #btc🫡

[Rowshan @rowshanchannel]

patience. Stay focused, stay positioned, stay Rowshan. 🟩
#Bitcoin #Crypto #BTC #Altseason #CryptoEducation #MarketUpdate #Rowshan

[Wheels @obscuresparrow]

follow for #alpha #MarketUpdates 🫡

[Rowshan @rowshanchannel]

$114K, the next momentum leg activates.

🎯 Target zone: $118K–$121K
This is how expansions begin — not with hype, but with quiet strength. Stay patient. Stay positioned. Stay Rowshan. 🟩
#Bitcoin #CryptoMarket #BTC #MomentumShift #CryptoEducation #Rowshan #Altseason