Bryan Jasker PT, DPT

CCO OVAL | NUPTHMS | Metabolic Fitness | Metabolic Flexibility | MetFlex Index | Lactate | Mitochondrial Rehab | The Oxidative Phenotype | Healthspan

[Bryan Jasker PT, DPT @oval_MetFlex]

Here is the link to our MetFlex Index paper. A lactate-based health and fitness assessment.

https://t.co/hobAkuDEsk

[Bryan Jasker PT, DPT @oval_MetFlex]

@sguyenet Partly explained by differences in where the fat is stored within muscle fiber and if/how mitos approximate and access lipid droplets?

[Bryan Jasker PT, DPT @oval_MetFlex]

Our Continous Lactate Monitor (CLM) prototype testing this week: 30 second sampling rate during a cycle-based test. On the right path.

Stay tuned...

[Bryan Jasker PT, DPT @oval_MetFlex]

@BenBikmanPhD @dan_hues @lowcarbGP @realDaveFeldman @BrownAdey @DoctorTro @PHCukorg @PHCAus @timspector @garytaubes Imagine the utility of a CGLM. In dev.

[Bryan Jasker PT, DPT @oval_MetFlex]

@MarcusMilione It is possible. We are building.

[Bryan Jasker PT, DPT @oval_MetFlex]

@feelthebyrn1 We've observed acute and substantially declines in lactate clearance capacity during respiratory illnesses. Usually see this impact within a few days lasting a few weeks. Never seen clearance return to baseline spontaneously thereafter. This effect may persist for some.

[Bryan Jasker PT, DPT @oval_MetFlex]

@BaptistHealthSF @JonFialkowMD Fun and insightful event with fantastic hosts! Thanks for letting me chat about maintaining metabolic flexibility in aging. Lots more to learn...

[Baptist Health @BaptistHealthSF]

The Lifestyle & Longevity Medicine Symposium brought together physicians and experts across disciplines to explore practical, evidence-based approaches to prevention, metabolic health, precision diagnostics, and emerging longevity therapeutics.

[Bryan Jasker PT, DPT @oval_MetFlex]

Is there a standard of practice to monitor resting lactate levels when dosing metformin? Curious bc anyone I've tested taking metformin had a resting [La] over 2 mmol and typically did not clear with light physical activity. When metformin held I saw normal patterns in lactate levels and clearance.

[Bryan Jasker PT, DPT @oval_MetFlex]

Metabolic Flexibility

Metabolic Flexibility refers to how efficiently your body processes energy like carbohydrates and fats. It’s mostly based on supply and demand, what’s available and what you’re doing or (or not doing). Losing flexibility (not talking about your hamstrings) is related to changes in metabolic health, typically not the good kind. It can be measured by a few methods, for example, with a mask measuring the gases you are breathing (RER) or by seeing how glucose and insulin respond over time to a sugary drink (OGTT).

OVAL measures metabolic flexibility during an exercise test by sampling lactate as the test increases in intensity. From the test results, we describe your status of your metabolic flexibility as the MetFlex Index, offering direct insight into your metabolic operating system.

Below is a comprehensive review on Metabolic Flexibility by Goodpaster and Sparks.

https://t.co/I43Gs8rCeJ

[Bryan Jasker PT, DPT @oval_MetFlex]

@Dan_Wyke @katiamek Submax protocols to just 1st lactate threshold are sufficient in my experience for diagnostics

[Bryan Jasker PT, DPT @oval_MetFlex]

@JohnGoldman Yes. And pretty much global at this point.

[Bryan Jasker PT, DPT @oval_MetFlex]

In her NYT article, “What Is ‘Metabolic Health,’ and Why Does It Matter?”, Author Nina Agrawal discusses dysfunctional metabolism and its impact on health and disease in the U.S. Often, conversations around the terms ‘metabolism’ or ‘metabolic’ are framed around nutrition, calories, weight, and obesity. As Nina mentions in her article, movement also plays a role in preventative strategies, noting the  public health recommendations of 150 minutes a week of moderate aerobic activity, alongside strength or resistance training. 

General recommendations are helpful for generating awareness but aren’t necessarily successful at the individual level since each of us differs in form and function and improving our metabolic health is not a one-size-fits-all solution. 

Our work at OVAL has been to create a science based, personalized movement program to reboot your metabolic operating system. Improving your body’s ability to manage stress and energy is key to restoring sustainable health. Over the next few months I will provide explanations for how OVAL measures and manages your metabolic health through movement. Stay tuned…

https://t.co/k68ocebZv7

[Bryan Jasker PT, DPT @oval_MetFlex]

@JohnGoldman You have visual comps or graph for lactate test 1 vs this most recent one? Great work John!

[Bryan Jasker PT, DPT @oval_MetFlex]

@MVAitor Rabinowitz lab doing solid work on metabolic flux

[Bryan Jasker PT, DPT @oval_MetFlex]

@johngoldman Thanks John. Appreciate you sharing the link to our paper.

[John Goldman ☀️ @JohnGoldman]

Interesting approach to assessing metabolic flexibility and its relationship to various health markers.

[Bryan Jasker PT, DPT @oval_MetFlex]

@SrihariNaiduMD @SandeepNathanMD @Babar_Basir @agtruesdell @SarasVallabhMD @adityadoc1 @SCAI @CRT_meeting @davebaran @thiele_holger @nymedcollege Would your profession find utility in a continuous lactate wearable that samples every 30 seconds for 2 weeks?

[Bryan Jasker PT, DPT @oval_MetFlex]

@hrv_tokyo We are currently in development

[Bryan Jasker PT, DPT @oval_MetFlex]

@Alan_Couzens "This is the way" - Midichlorians

[Bryan Jasker PT, DPT @oval_MetFlex]

@StuartBlitz Try a @portilloshotdog double cheeseburger. Best I've had in a while.