Pavan Bachireddy

Assistant Prof @MDAndersonNews. #immunotherapy single cell #genomics #leukemia. Alum @BrighamMedRes, @StanfordMed || tweets: my own

[Pavan Bachireddy @pbachi]

1/ Excited to share how T cell therapies kill #leukemia!! multi-omics + new #computational #singlecell tools for longitudinal analysis 👉unexpected answer! https://t.co/t3scnSunRY

*👏* @elhamazizi! 🙏 @dpeer Cathy Wu @MDAndersonNews @CPRITTexas @ColumbiaBME @sloan_kettering

[Pavan Bachireddy @pbachi]

Congrats to @dust_im_md for an outstanding talk from our lab! 🙏🏽 #sitc25 and @MDAndersonNews. Wonderful presentations from all #trainees at the session.

[Dustin McCurry @dust_im_md]

Great to present at #SITC25 and receive a YIA! We report that genomic drivers can directly edit (ie. not transcriptional) the immunopeptidome, shaping the quantity and quality of antigens for T-cell immunotherapy. Excellent mentorship from @pbachi @ShuklaSachet @jmolldrem

[Pavan Bachireddy @pbachi]

@JMSchenkel @MDAndersonNews thank you @jmschenkel for the kind 👊!

[Pavan Bachireddy @pbachi]

🙏🙏 to @MDAndersonNews, @RiceEngineering, @CPRITTexas, @evansfoundation, @DamonRunyon, @break_cancer, @theNCI, @PhRMAfoundation, and #patients and #families! #CancerResearch

[Pavan Bachireddy @pbachi]

Thrilled to share our 1st preprint (!) on @biorxiv “Molecular and cellular dynamics of measurable residual disease (#MRD) progression in myelodysplastic syndromes (MDS).” Led by the indefatigable Yu-Hsiang Chen in the lab (https://t.co/l8hxICNpJg).

👉👉https://t.co/1rFRt1qFws

[PhRMA Foundation @PhRMAfoundation]

#PhF25 awardee Yu-Hsiang Chen, a postdoc @MDAndersonNews, is using single-cell technology to study #cancer cells that remain after stem cell transplant. Understanding these cells could help develop better treatments. @pbachi

Watch the full interview: https://t.co/UIpzszVfF6

[Pavan Bachireddy @pbachi]

tl;dr
CARAMEL-seq reveals the 1) biology of MRD (sensitive detection, shared molecular signatures) + 2) principles of progression (subclonal competition, cytokine driven maladaptive signaling) = eco-evolutionary framework for MRD.

[Pavan Bachireddy @pbachi]

@JLFLitfest Hello - I would love to inspire my daughters at the Houston Friday event!! is it possible to get 3 tickets?? 🙏🏽 Pavan

[Pavan Bachireddy @pbachi]

Congrats @dust_im_md on a *fantastic* #ASH2023 oral presentation - the first from the Bachireddy Lab!

[Pavan Bachireddy @pbachi]

@Aiims1742 @MDAndersonNews @DraettaG Thank you @Aiims1742 for the 👊🏾!

[Pavan Bachireddy @pbachi]

@GhayasIssa @doctorpemm @Nature @MDAndersonNews Congrats Gus!! Really cool work

[Pavan Bachireddy @pbachi]

Thank you @CellReports for recognizing our work!! 🙏🏽 @dana_peer @elhamazizi Cathy Wu and Co for showing that #teamworkmakesthedreamwork!

[Elham Azizi @elhamazizi]

Delighted to see this work with @pbachi @dana_peer Cathy Wu highlighted in the top 10 Best of @CellReports among 1,500 articles in 2021-2022!! 😃 https://t.co/iPofRMrCQA

[Pavan Bachireddy @pbachi]

@SteidlUli @mkonople @ae_cancercenter Congratulations @mkonople ! Really appreciate all of your advice and guidance. @ae_cancercenter is very lucky to get you!!

[Uli Steidl @SteidlUli]

I am thrilled to announce that world-class physician scientist and leukemia researcher Dr. Marina Konopleva @mkonople has joined us at Montefiore Einstein Cancer Center @AE_CancerCenter as the Director of the Leukemia Program, and Co-Director of our new Blood Cancer Institute !!

[Cancer Discovery @CD_AACR]

From the June issue: Integrated Multiomic Profiling Identifies the #Epigenetic Regulator PRC2 as a Therapeutic Target to Counteract #Leukemia #ImmuneEscape and Post-Transplantation Relapse, by @GambacortaV, @DiMiccoLab, @vago_luca et al.
https://t.co/T7YhNRvEXl
@SanRaffaeleMI