When proteostasis fails, Nrf2 gets a bit confused and does silly things. Pak2 helps protecting the heart by telling Nrf2 to calm down.
Pak2 Regulation of Nrf2 Serves as a Novel Signaling Nexus Linking ER Stress Response and Oxidative Stress in the Heart https://t.co/YbD9vfJY0h
If capitalism truly rewarded skill or intelligence, the richest people would be neurosurgeons, engineers, and scientists.
If it rewarded talent, it would be artists, writers, and creators.
If it rewarded hard work, it would be cleaners, laborers, and service workers.
But it’s none of them.
The problem with ethnonationalism is that it actually makes integration and belonging to Britain meaningless.
If we are going to be judged for our race or skin colour, regardless of how much we contribute to Britain, what's the point of integrating and contributing then?
Restore Britain supporters have told me, over and over again, that even my children (born to an English) aren't British because they're "mixed race".
So, they're basically arguing that about 25% of the people in this country aren't British, regardless of how much they integrate, contribute, or live this country.
This is neo-Nazi level "blood purity" madness.
Dear University staff, reducing departmental costs and saving you time is important to us. That's why we insist you use a travel booking system that overcharges us and operates less effectively for you than a basic google search.
Angiotensin metabolism is not only key for blood pressure regulation, but Its control can also locally keep a healthy heart. This is the story on how cardiac PRCP activity protects cardiomyocytes from hypertensive hypertrophy.
https://t.co/GLv5IVWsi6
Our paper on Nuclear and Cytoplasmic Spatial protein quality control is finally out in NCB!!
Many many Congratulations to @EmSontagMU 😍 it was a great pleasure learning from you, and working with you!
Please pass and have a look :)
https://t.co/dD2yR4juTm