Víctor Castro Fern..

Proteinólogo - académico en @LabBqUchile - UChile ⚗️
Investigo la evolución y estructura de proteínas.

[Víctor Castro Fern.. @vcasfe]

Presentamos evidencia de un nuevo principio evolutivo a nivel molecular: la Deriva Mecanicista--> Functional conservation with mechanistic drift: AMP activation in the evolution of archaeal sugar kinases https://t.co/CxKORRJOYX

[Exequiel Medina @exe_1987]

Entiendo el espíritu del recorte en el presupuesto para Fondecyt Reg 2025, pero… ¿26 millones no será mucho?. Tengo menos presupuesto para gastos op que en mi iniciación. @ANID_Chile

[Víctor Castro Fern.. @vcasfe]

Nuevo preprint de nuestro laboratorio

[Laboratorio de Bioquímica y Biología Molecular @LabBqUchile]

Our preprint is out: Glycogen phosphorylase from the methanogenic archaeon Methanococcus maripaludis: Unique regulatory properties of a pyridoxal 5’-phosphate independent phosphorylase https://t.co/xVRZ4bkvVk

[Centro de Biología Estructural del Mercosur @red_cebem]

“This is a starting point for synergistic work that will allow us to grow and strengthen networks in Latin America”

📣 @LiaPietrasanta, Chair of @LatamBioimaging shares her view on the significance of signing this MOU between our networks.

#ImagingTheFuture
#LABIxSuperres2024

[R🅰️ul 🅰️raya @Vulcanisaeta]

📢 We are excited to share our new preprint presented at the Mechanics of Hearing 2024 conference! 🎉
Check it out here:
#Hearing #Biophysics #Science
https://t.co/aHL9BfzoLH

[Centro de Biología Estructural del Mercosur @red_cebem]

Discover how CEBEM's fellowships enhanced Seba's research journey! 👉 "I learned from cryo-electron microscopy specialists at @NanotecLNNano, who were very willing to help people like me, who were still learning."

#ImagingTheFuture @cziscience @Embiidz

[Centro de Biología Estructural del Mercosur @red_cebem]

¡Sumate a la VI Reunión de la Asociación Latinoamericana de Cristalografía en Montevideo, Uruguay! 🧪🌍

📅 Para asegurar tu lugar y garantizar que tu resumen sea incluido en el libro del evento, regístrate antes del 10 de agosto: https://t.co/gp5b6mmS0I

¡Además hay bonus! 👇

[Víctor Castro Fern.. @vcasfe]

Nuestro último trabajo de @LabBqUchile está disponible en MBE:
Deciphering Structural Traits for Thermal and Kinetic Stability across Protein Family Evolution through Ancestral Sequence Reconstruction https://t.co/lQEzE5lK8A @AnidInforma #fondecyt @CNPEM @JorgeBabul

[Víctor Castro Fern.. @vcasfe]

https://t.co/9En8jRXJJj nuevo doctor del @LabBqUchile 🎉

[Centro de Biología Estructural del Mercosur @red_cebem]

Our Single Particle Cryo-Electron Microscopy international course is starting now!

We will learn hands-on this complex technique so that students from Argentina, Brazil, Chile and Uruguay can implement it in their home laboratories 🔬

Here we go 💪🤓

[Science Magazine @ScienceMagazine]

In two independent Science studies, researchers used time-resolved crystallography at an x-ray free electron laser to capture the process of #DNA repair from picoseconds to microseconds.

Learn more on #DNADay ⬇️
📄: https://t.co/GlRfbfSUt6
📄: https://t.co/R22Dk0HVyo

[EMBL-EBI @emblebi]

The new @EMDB_EMPIAR cryo-electron tomography (cryo-ET) browser allows you to see proteins up close in the cellular environment.

Over 1,800 high-resolution reconstructed tomograms from cryo-plasma-FIB milled Chlamydomonas reinhardtii cells are available.

https://t.co/YTgnVvn46i

[Centro de Biología Estructural del Mercosur @red_cebem]

🔬💪 We're excited to present the global experts who will be guiding you through the fundamentals of Cryo-Electron Microscopy at @IBR_CONICET.

Hurry! ⏳ This is the final week to apply: https://t.co/lS33vksdcD.

#ImagingTheFuture

[Itai Yanai @ItaiYanai]

4. The "Molecular Clock" allows us to quantitatively study the evolutionary process. As genetic mutations accumulate at roughly constant rates in certain DNA sequences, by comparing the sequences of different organisms, we can infer when any two species last shared an ancestor.

[Víctor Castro Fern.. @vcasfe]

Perdida de cola en hominidos podría estar relacionada a la aparición de espina bífida en el desarrollo, esto debido a una pequeña alteración genetica 👀

[Itai Yanai @ItaiYanai]

How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. https://t.co/0ZR8aH23PJ @BoXia7

[Itai Yanai @ItaiYanai]

How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. https://t.co/0ZR8aH23PJ @BoXia7

[Víctor Castro Fern.. @vcasfe]

@marenas5000 @LabBqUchile Justamente, la combinación de AI, partículas individuales y tomografía nos llevarán a otro nivel de estructuras en biología.

[Víctor Castro Fern.. @vcasfe]

Great CryoEM course in Sao Paulo Brazil 😊. 2 very intense weeks of learning and also a slap in the face of reality in the discipline. @LabBqUchile #spcryoEM #cryoEM

[Centro de Biología Estructural del Mercosur @red_cebem]

Siempre seguimos mirando al futuro 🙌  @TatoVila_1962 nos cuenta cómo surgió #CEBEM a partir de un sueño común de un grupo de amigos apasionados por la Ciencia y la Biología Estructural!

[Víctor Castro Fern.. @vcasfe]

El "Loco" chileno (Concholepas concholepas) está participando en un concurso internacional llamado Molusco del año . A varios científicos chilenos nos ayudará la secuenciación de su genoma. Voten por favor!!! Termina hoy 12 de la noche @JorgeBabul @uchile
https://t.co/jbHqcYHouj