Pierre-Emmanuel Bonté

30 ~ 🇫🇷~ Data scientist / Computational biologist ~ Immunology ~ PhD ~ I love coding 👨‍💻

[Pierre-Emmanuel Bonté @pe_bonte]

One month ago I defended my PhD thesis entitled « Discovery and characterization of tumor specific transposable elements as novel potential biomarkers » ! Really grateful for everyone at @institut_curie and @ImmunCancer_IC for the support all these years !

[Pierre-Emmanuel Bonté @pe_bonte]

@YagoArribas @CellCellPress Congrats Yago !!! 👏👏👏 So happy for you, you really are the best 😁

[Yago Arribas @YagoArribas]

Not easy to describe the emotions of seeing our work published in @CellCellPress ! We explored how novel isoforms emerge during evolution through the exonization of Transposable Elements. Exonized TEs modify the functions and structures of host proteins.
https://t.co/s6nkORnGbE

[JimeTosello @jimena75656604]

I am happy to share the terrific work of Elisa Bonnin and our team! CD74 supports accumulation and function of regulatory T cells in tumors | Nature Communications https://t.co/d3gfYBX14o

[Journal of Experimental Medicine @JExpMed]

Lucibello, Lalanne, Le Gac, Lantz et al. @institut_curie show that the poor prognosis of M3 uveal #melanomas generates a local adaptive immune response, while the better prognosis of SF3B1-mutated uveal melanomas induces a systemic immune response https://t.co/K1o4JGNzTv

[Ensembl @ensembl]

ATGGAGAGGAGGTACTGCCACAGGATCAGCACCATGGCCAGCGCCAACGACGCCCACGCCCCCCCCTACAACGAGTGGTACGAGGCCAGG from everyone at
@ensembl

[Pierre-Emmanuel Bonté @pe_bonte]

@YohanGRBR @NatureCellBio Félicitations Yohan ! 👏👏👏

[Pierre-Emmanuel Bonté @pe_bonte]

Particularly, I would like to extend my gratitude to Christel Goudot and Sebastian Amigorena for their invaluable help and leadership throughout this project and during all my #PhD.

[Pierre-Emmanuel Bonté @pe_bonte]

Really happy to share my PhD work recently published in @SciImmunology in which we study the impact of T cell exhaustion on transposable elements (TEs) and explore their potential as biomarkers in #cancer and #immunotherapy
https://t.co/pvSEuOxrgj

#ScienceImmunologyResearch 🧵⬇️

[Pierre-Emmanuel Bonté @pe_bonte]

This work would not have been possible without the exceptional contributions of many individuals, including the remarkable work of @mt_christin , @C_Alanio, @MarianneBurbage, @YagoArribas and many more as well as the great support of @ImmunCancer_IC and @institut_curie.

[Science Immunology @SciImmunology]

A new study by @institut_curie scientists shows expression of transposable elements is repressed in exhausted #Tcells and could be applicable to biomarkers for response to #CheckpointInhibitor therapy.

📄: https://t.co/yV5dZqzXpc

[Pierre-Emmanuel Bonté @pe_bonte]

@octupls @institut_curie @ImmunCancer_IC Thank you Paul !

[Pierre-Emmanuel Bonté @pe_bonte]

One month ago I defended my PhD thesis entitled « Discovery and characterization of tumor specific transposable elements as novel potential biomarkers » ! Really grateful for everyone at @institut_curie and @ImmunCancer_IC for the support all these years !

[Pierre-Emmanuel Bonté @pe_bonte]

Finally thank you to all my friends and family for the amazing support during my academic career and all my life ❤️

[Pierre-Emmanuel Bonté @pe_bonte]

Many thanks to Sebastian Amigorena and Christel Goudot ! Doing my PhD under your supervision was such a great experience as I could learn a lot and grow as a scientist. Also many thanks to the Amigorena team as this PhD wouldn’t have been the same without you.