Heading back home from a fantastic #EASD2023 meeting with new ideas & inspiration. Thanks to @EASDnews@EASDacademy for the opportunity to present & recognition of our work 🏆 My gratitude goes to my mentors Hans Hauner and @MelinaClaussnit & team for the continuous support 💫
A new proof-of-concept study introduces LipocyteProfiler, a powerful and inexpensive bioimaging tool that uses 3,000+ cellular features to explore metabolic traits and disease biology. https://t.co/I7jItwLTmV
@NatMetabolism We got the cover of @NatMetabolism! A huge shout-out to @PhilKubitz, a wonderful trainee in the lab, for his cover suggestion! Interested in the #V2F work behind it? Read https://t.co/PvIazHg6cg and the fantastic News & Views from @CebolaLab and @Hammaude along with it!
Very elegant paper from @MelinaClaussnit lab, exploring the mechanism of effect at a lipodystrophy-like T2D locus, implicating adipose actin cytoskeleton remodelling https://t.co/ghSqYw3FQS (News & Views by myself and @CebolaLab! https://t.co/VGufYniZob) 🙏
Online now! A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes https://t.co/yB6Ffu6qlF
New in @NatureComms led by @saaket_agrawal and @wallacemwang:
Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots
as quantified by MRI in ~40K participants of the UK Biobank
https://t.co/EIwXU6KATI
New from @MarcusKlarqvist + @saaket_agrawal!
Beyond overall adiposity, DISTRIBUTION of fat is a key driver of cardiometabolic health
Most prior studies used medical imaging (DEXA, MRI, CT) to quantify
Can we accurately estimate distribution with just a person’s silhouette?
I am excited to share our preprint together with @BMRRgroup@StfnnftS@CNellaker@ceclindgren@MelinaClaussnit on transcriptome and fatty-acid signatures of adipocyte hypertrophy and their non-invasive MR-based characterization in human adipose tissue.
https://t.co/izXmEeYYVg
Tomorrow I will present our latest finding of an insulin inhibitory receptor in beta cells, registration is still open. RTW for colleagues interested in #insulin and #betacells and #diabetes
Our (@WFlorianFricke@DanielPodlesny) new metaanalysis of the neonatal #microbiome, maternal strain inheritance, and persistence into adolescence is out: https://t.co/XvDe3qkb2d. We used our SameStr tool to identify and visualize shared strain networks. (1/4)