RCTs in critical care, history, major challenges & limitations, recent developments trying to solve some of these
📊conventional & novel RCTs
📊rationale for choosing methodological approach (advantages/potential disadvantages - pros/cons)
@CritCareReviews
https://t.co/kjCw7dFuou
Surviving sepsis campaign: international guidelines for management of #sepsis and septic shock 2021 @ESICM@SCCM
Released simultaneously in @yourICM@CritCareMed
Pleasure to be part of this great team
Links:
https://t.co/jd17hzeGxP
https://t.co/itHTIy2kT1
Just enrolled 100th patient to #MegaROX from Tokyo. Grateful for Jikei ICU team's effort in the midst of the biggest COVID wave we've ever had.
@DogICUma@DianeMackle
My interview with Alain Combes powered by
@yourICM about our latest publications implementation of new ECMO centers during the COVID-19 pandemic https://t.co/vL1WJtKZ3T
SR of 7 RCTs of early mobilization in ICU patients: https://t.co/aJgSzICr36
Generally small studies, but promising findings. Needs further research. Should #DVT be a standard endpoint in interventions that include #ABCDEF bundle or any component (sedation, weaning, mobilization)
It is my pleasure to present State-of-the-Art on #VTE prophylaxis in #ICU patients at #ISTH2021
1. Heparin (unfractionated or LMWH)
2. IPC if pharmacologic prophylaxis is contraindicated
3. Early mobility
4. Avoidance of femoral venous catheters
What is the effect of dexmedetomidine on temperature? For a detailed understanding have a look at this study👇
The Effect of Early Sedation With Dexmedetomidine on Body... : Critical Care Medicine https://t.co/k5lebS3AYe
High-resolution MRI and histopathological study of the brains of patients who had died from #COVID19 showed punctate hyperintensities and punctate or linear hypointensities. No evidence of active viral infection was found.
Thank you @DogICUma for the opportunity to participate in this important trial. Huge credit to the #MegaROX team of respiratory therapists who are doing an amazing job
We are now up to 5 out of 100+ planned sites recruiting into the #MegaROX trial. I already like the shape of the recruitment graph. At peak recruitment I hope we will enrol more than 100 patients per DAY.
خبر؛.
انضمام أكثر من 100 ألف شخص لمنصة التطوع الصحي بعد ساعتين من انطلاقها.(الإخبارية)
(تطوع يعني بدون مقابل مادي ويوجد مخاطرة)
لمن يريد اي يعرف ماذا يعني هذا الوطن لأهله.
Further remarks on COVID-19 pneumonia. Would you treat these two patients, with similar hypoxemia (both with PaO2/FiO2 < 100 mmHg) with the same high PEEP?
@yourICM @Luigi_ICM @BusanaMattia
https://t.co/OwCgDwhr5G
#covid19FOAM#coronavirus updates from the CCM-L list. Troubling reports from Italy, as this sounds like a rather sicker population than described in other settings. Note the high prevalence of shock and fairly young age bracket. (shared with permission)
Preplanned observational study: Twice‑weekly ultrasonography was associated with 4-fold increase in DVT detection, earlier diagnosis of #DVT and #PE, and possibly lower 90‑day mortality
@preventstudy#SCCTG#VTE@yourICM
https://t.co/ZjS9ObuRw1