“Be a communist when you are with your family.
Be a socialist when you are with your friends.
Be a capitalist when you are anywhere else.”
Naval Ravikant - one of the best jre episodes ever
@WilliamAird4 Dr Aird, although the total RBC mass may be preserved, maybe the "anemia" is dilutional, as splenomegaly is known to increase the circulating plasma volume?
@WilliamAird4 Only 3 causes of microcytic erythrocytosis per Harrison : beta thal trait, P vera, hypoxic erythrocytosis. Now to explain thrombocytopenia, hemoglobin on the higher side: Maybe p vera progressing to myelofibrosis, p vera with effect of therapy, p vera with concomitant itp?
@WilliamAird4 1. O.1 per day if no hematopoiesis.
2. Sticky RBCs decreasing counts more relative to Hb
3. Reticulocytes are big
4. Same reason as point 2
5. Blobs of fused RBCs have relatively more volume than Hb
6. Rdw cv takes mcv into account, rdw sd doesnt
@EM_RESUS TCA overdose ---- sinus tachycardia due to muscarinic blockade, prolonged qrs due to Na channel blockade, typical rsR' morphology in avR
DDx --- hyperkalemia (greater mimicker), v tach, wpw
If you simply remain with the problem, don't run away from it or find escape in some distraction, the problem will either be solved or dissolved.
No problem can survive confrontation. Problems exist only in the darkness of unawareness.
Signs of growth:
— You are calmer, less reactive
— Your writing is more concise, simpler
— Your friends are fewer, more loyal
— You think and live for yourself
— Short-term pleasure gets boring
— You help people
— You stress-test your beliefs
— You do things more slowly