Paul W. Hook

Assistant Editor, The American Journal of Human Genetics @AJHGNews (Posts and views are my own)

[ASHG @GeneticsSociety]

Meet AJHG (@AJHGNews) author and researcher Lorin Crawford, PhD. Learn about their experience of publishing in AJHG and their research: https://t.co/0iYTvWJhiG #ASHG #HumanGenetics

[ASHG @GeneticsSociety]

Meet AJHG (@AJHGNews) author and researcher Zeynep Coban-Akdemir, PhD. Learn about their experience of publishing in AJHG and their research: https://t.co/j0NNUvbQYJ #ASHG #HumanGenetics

[ASHG @GeneticsSociety]

Seeking to improve PRS predictive performance for admixed individuals, @Yunfeng_Ruan, @pnatarajanmd, & co., authors of @AJHGNews' latest article, present DiscoDivas—a genetic-distance-assisted framework that interpolates PRSs across an ancestry continuum: https://t.co/ybQ5sCsKIW

[Konrad Platzer @platzer_k]

The works was published in @AJHGNews w/ @ahoischen last week. Great work! 👌 #eshg2026

https://t.co/dw5FItRcI9

[AJHG @AJHGNews]

🧬New from @mathiesoniain & co
📄Genome-wide analysis implicates inner ear development in Ménière disease
https://t.co/dwsjD3mn41

[AJHG @AJHGNews]

🧬New from @eichlerlab
📄Complete chromosome 21 centromere sequencing of families with Down syndrome
https://t.co/weoC29rXJs

[AJHG @AJHGNews]

🧬New from @DrTMersha & co!
📄Trust, mistrust, and the promise of #AI in #genomics for African populations
https://t.co/udqHTerzeN

[BCM Department of Molecular and Human Genetics @bcmgenetics]

Researchers at @bcmgenetics with the Undiagnosed Diseases Network, & international collaborators, identified a new genetic disorder tied to TMEM63B variants causing severe early-onset lung disease. Read more about the discovery published in @AJHGNews : https://t.co/9A7CI131m5

[ASHG @GeneticsSociety]

.@HGGAdvances latest article presents a multiomic study of idiopathic scoliosis that helps to elucidate disease mechanisms & enable therapeutic and biomarker development: https://t.co/3y7i953xQe #ASHG #HumanGenetics #GeneticsDiscoveries

[ASHG @GeneticsSociety]

.@AJHGNews sat with Xinyu Sun, in the latest "Inside AJHG" to discuss his recently published paper, “Multi-ancestry transcriptome-wide association study reveals shared and population-specific genetic effects in Alzheimer’s disease.” ➡️ https://t.co/P1VOEis2th #ASHG

[AJHG @AJHGNews]

🧬New from Mechol & colleagues!
📄Bi-allelic loss-of-function variants in TMEM63B cause syndromic surfactant dysfunction disorder
https://t.co/vItleJOva5

[Audra Iness, MD, PhD @AudraIness]

Excited to share our new paper: Bi-allelic loss-of-function variants in TMEM63B cause syndromic surfactant dysfunction disorder. Thank you to my co-authors, patients, & their families for making genetic disease discovery possible. @AJHGNews @bcmgenetics
https://t.co/Dc48ZXUM6n

[Weng Khong Lim @biowengkhong]

New @AJHGNews paper from our team describing a new autosomal recessive disorder caused by #TMEM63B deficiency. A good example of how rare disease gene discovery depends on connecting clinicians and researchers who are each seeing only part of the picture. https://t.co/TYFFuZBNGd

[AJHG @AJHGNews]

🧬New from @ahoischen & co!
📄HiFi sequencing accurately identifies clinically relevant variants in paralogous genes
https://t.co/vCsTtIZDKt

[ASHG @GeneticsSociety]

.@ZhandongLiu, @hyunhwan_jeong & co of @AJHGNews latest article presents MARRVEL-MCP—a natural-language interface that equips LLMs w/ 44 genomic tools for rare disease variant interpretation: https://t.co/GWQu6FVYGH
Learn more during our 7/8 LIVE webinar: https://t.co/un2LpYnG4l

[AJHG @AJHGNews]

Our June issue is online!
Check it out: https://t.co/yT3q5AtjkC

[AJHG @AJHGNews]

🧬New from Dai et al!
📰Identifying condition-related cell-cell communication events using supervised tensor analysis
https://t.co/srh6N5vPyr

[AJHG @AJHGNews]

Remembering Pat Jacobs
https://t.co/wIckkPYdqg

[ASHG @GeneticsSociety]

By integrating genetics and functional assays, @HGGAdvances' latest study identifies HAVCR1 as the effector gene at the hyperlipidemia-associated 5q33.3 locus, revealing how multiple regulatory mechanisms can converge on a single GWAS locus: https://t.co/62Azs5XHpa #ASHG

[From the Labs at Baylor College of Medicine @BCMFromtheLabs]

This new computational approach allows users to ask questions in plain language, such as, “Is this BRCA1 #gene mutation linked to #cancer?” @ZhandongLiu @hyunhwan_jeong et al @AJHGNews @bcmhouston @TexasChildrens #AI https://t.co/mReHKGMJbz