Brendon Boot, MD

neurology, neuroscience, cell and gene therapy enthusiast, surf fanatic

[Brendon Boot, MD @rabdo1]

@chrishemsworth @NatGeo G'day Chris - we're a Sydney-based stem cell biotech working on a treatment for Alzheimer's (https://t.co/IFdwaRzUSF). We're legit. Eli Lilly are investors. We're connected to folks u worked with @ UNSW. Can I tell u about it sometime, please? I sent an email to Mark Morrissey.

[Hugh Grant @HackedOffHugh]

For anyone who has been interested in my lawsuit against the Sun, the news is that  I’ve had to settle my claim out of court before it gets to trial. A 🧵…

[Elon Musk @elonmusk]

Livestream of @Neuralink demonstrating “Telepathy” – controlling a computer and playing video games just by thinking

[David Pocock @DavidPocock]

Do Australians have a right to know who's buying access to politicians?

[Tim Ferriss @tferriss]

There are rare times when I feel like I’m in the zone. Those are great.

Then there are times when I ask myself, “How in holy hell have I become the janitor of a mountain of bullshit?”

Put another way, sometimes you’re the boxer and sometimes you’re the punching bag. We all get our turn as the punching bag. As far as I can tell, it doesn’t matter how “successful” you become, you have always grabbed a number at the deli counter of getting your ass kicked by the universe.

During these periods of fire fighting, I get fidgety and frustrated. I feel like I’m treading water, and patience wears thin, especially with myself.

My instinct is to try to fix things as quickly as possible. That’s all well and good, but I’ve realized that from a place of “WTF?!,” I often rush and create more problems. This is particularly catastrophic when I try to sprint immediately upon waking up.

The mantra that saves me is simple:

“Make before you manage.”

Each morning, before plugging holes, fixing things, calling vets, answering text messages, or delegating things, this mantra is a reminder to make something.

Even the most time-sensitive items can usually wait 60 minutes, and by make something, I mean anything.

You just need to feel like you’ve pushed a millimeter ahead in some creative direction.

For me, even a 90-second video of calligraphy could set a better emotional tone for the day, helping me to more calmly handle problems. Or maybe I attempt to jumpstart my writing with an Instagram caption. It’s practically nothing, but it’s enough. Even token efforts allow me to reassure myself with “Don’t worry. You did produce something today.”

The psychological difference between zero acts of creation and one act of creation, no matter how small, is impossible to overstate. If you’re lucky, sometimes that one idea, one sentence, or one shitty first draft can turn into something bigger. But the point is to be able to say to yourself, even for five minutes, “Hark! I am a creator, not just a janitor of bullshit! Here is proof that I can—and will!—do more than just manage minutiae… ”

We all spend time on the struggle bus. At the very least, this mantra has helped me to find a window seat when it’s my turn.

When in doubt, try it out: make before you manage.

[Lawrence M. Krauss @LKrauss1]

Wow! This is another planet!!! Rovers rock!

[Brendon Boot, MD @rabdo1]

@Tesla_Optimus The world changed today.

[Linus ✦ Ekenstam @LinusEkenstam]

(not) Johnny Cash singing Barbie Girl

People using AI tools are creating the most insane things.

links in next tweet

[Denis Wirtz @deniswirtz]

Interesting.
Number of highly cited scientists/engineers by country among top 100K most cited in the world and those numbers normalized by size of country.

(Source: https://t.co/2RXLOjwCGM)

[Tim Minchin @timminchin]

Here's a short - arguably funny - lecture from my show 'Back'.

https://t.co/6kdqkcB4gl

[Teresa Kubacka @paniterka_ch]

Today I asked ChatGPT about the topic I wrote my PhD about. It produced reasonably sounding explanations and reasonably looking citations. So far so good – until I fact-checked the citations. And things got spooky when I asked about a physical phenomenon that doesn’t exist.

[Brendon Boot, MD @rabdo1]

@DrSynbio @StrandTx Congratulations Jake and team. A great round in tough times.

[Brendon Boot, MD @rabdo1]

@IPGroupplc I'm thrilled to be working with such a fantastic group of investors and innovators, and excited by the huge potential and bright future for #Ausbiotech. There is so much great science here, we need to move it to the clinic!

[IP Group - visionary ventures @IPGroupplc]

IP Group welcomes Dr Brendon Boot who has joined our Australia team as our first Entrepreneur in Residence.

Brendon is a neurologist with extensive clinical and research experience at Mayo Clinic and Harvard Medical School.

#backinginnovation #neurology

[Alex Holley @AlexHolleyFOX29]

My coworkers show no mercy😩🤣

[Oded Rechavi @OdedRechavi]

Multiomics

[Ragged Trousered Philanderer @RaggedTP]

Spike Milligan on Prince Charles in 1994

[kalialabs @kalialabs]

Our team @kalialabs @KBI_UHN, in an exciting collaboration with @DrNirLipsman @Sunnybrook, demonstrates safe opening of the blood brain barrier using focused ultrasound to deliver a therapeutic in a specific brain region in #ParkinsonsDisease.
Details: https://t.co/RStuAsO7EA

[Jake Becraft @DrSynbio]

Incredibly exciting news to announce our recognition as a Fierce 15 company!

I have read this list every year for the next up-and-comers in the biotech industry worldwide. Now to be included is an amazing testament to the incredible work our team is doing!

#mRNA #innovation

[Brendon Boot, MD @rabdo1]

@DrSynbio This is not the least bit surprising.