Rafael Schulman

Physician Scientist in-training @ SUNY Upstate. Thinking of space and time (ie: spatially mapping viral phylogenies). Past:NYGC,C2i Genomics. For fun:🏉🚴🔊🎶

[Rafael Schulman @RafaelSchulman]

@simonsarris

[Rafael Schulman @RafaelSchulman]

@AviSchiffmann cool hat

[Thomas Geijtenbeek @tgeijten]

Trying to teach my new model to run using reinforcement learning (Hyfydy + depRL)

[Rafael Schulman @RafaelSchulman]

@You_Found_Nimmo tossed my nephew a ball between innings at the @Mets game today… made the kid’s day!! Thanks Brandon!!!

[Nicolas Robine @notSoJunkDNA]

scCircle-seq unveils the diversity and complexity of extrachromosomal circular DNAs in single cells
https://t.co/kBl4M5g93G

[Rafael Schulman @RafaelSchulman]

@nickfloats It seems to have the eye in the sky deep in its weights. This was "imagine -s 1000"

[Ash Jogalekar @curiouswavefn]

1/n: There are some academic papers that are so brilliantly and so accessibly written and so universal in scope that they transcend disciplines and stand as timeless testaments to both great thinking and great writing. Here's a short personal selection:

[Nature Methods @naturemethods]

DoTA-seq utilizes droplet microfluidics to isolate, lyse and amplify target genetic loci for high-throughput single-cell sequencing of microbial populations.
@oventurelli2 @UWBiochem @FreemanLan2

https://t.co/oDKamlJe1a

[Roxana Daneshjou MD/PhD @RoxanaDaneshjou]

I’m half tempted to do an “understanding medicine” for engineers just to help explain how much nuance and complexity there is (which is an important consideration when making design choices for AI models).

[Rafael Schulman @RafaelSchulman]

@ethanblinck yes

[Bo Wang @BoWang87]

Interested in LLMs for genomic research but don't know where to start? looking for a review/survey to get started in this field? 👇👇😀

I am very excited to share that our review paper titled "To Transformers and Beyond: Large Language Models for the Genome" is now available as a preprint (https://t.co/U24TUSseNr)! Our review unveils a revolution in genomics analysis with Genome LLMs. 🧬

🔍 What's Inside:
✅ The power & challenges of transformers in genomics.

✅ Cutting-edge models like HeynaDNA and scGPT & their impact.

✅ Deep dives into Enformer, DNABERT, and other Genome LLMs.

🌍 Why it Matters:
1. GPT-4's influence reshapes AI in genomics.
Unmatched insights into transformers' role in genomics.

2. Critical analysis of new models, addressing interpretability, privacy, & computational needs.

3. Essential for computational biologists & computer scientists to navigate the future of genomic data analysis.

This is a work led by the amazing PhD student, Mica Consens, in the lab! Also, a huge collaborative work with lots of field leaders @fabian_theis @genophoria @MKarimzade @michaelwainberg and Alan Moses!

@UofT @VectorInst @UofTCompSci @UofT_LMP @UHN @pmcc_ai @UHNAIHUB

[Alejo Rodriguez-Fraticelli @AlejoFraticelli]

One of my favorite things about the hematopoietic system is how it basically produces micromachines instead of your textbook “cells”. Many are anucleated or weird-shaped, packed full with the products of just a few genes, or even exploding if you tickle them.
Such a cool system!

[Rafael Schulman @RafaelSchulman]

@nntaleb Would be interesting to think about how to frame this as a testable hypothesis

[Jeremy Howard @jeremyphoward]

I just uploaded a 90 minute tutorial, which is designed to be the one place I point coders at when they ask "hey, tell me everything I need to know about LLMs!"

It starts at the basics: the 3-step pre-training / fine-tuning / classifier ULMFiT approach used in all modern LLMs.

[françois vogel @_francois_vogel]

time and space jump

[Rafael Schulman @RafaelSchulman]

@joejanizek Can you provide a reference with discussion about the problems with doing this?

[Lex Fridman @lexfridman]

Beautiful 60-day timelapse of a bird building a nest and raising her kids until they fly away from home. This is the magic of life.

[Danielle Fong 🔆 @DanielleFong]

good summary about the floaty rock drama so far

“if you’re not following LK99, you’re missing out on the most fun thing happening or the internet now. Feels like the old internet.”

https://t.co/ETlt031ObZ

[Savas Tay @SavasTay_UChi]

@gilbertjacka @KnightLabNews @StevenSalzberg1 this is science!

[Rafael Schulman @RafaelSchulman]

@shaarsh2 Plastic waste