Purple hands and purple feet of Multiple System Atrophy. This is a vasomotor autonomic dysfunction and nice paper in @journal_PD by Campese and colleagues.
"Study challenges assumptions about migraine & brain health, finding no significant link to structural changes via MRI markers. Reassuring news for migraine sufferers, underscores need for further research. #Migraine#BrainHealth#headache#neurology
https://t.co/Lg3Y5RFgjw
This study assessed duration of benefit and risk of clopidogrel-aspirin in patients with mild ischemic #stroke or transient ischemic attack. Learn more: https://t.co/Kly9tcts5R
Watch this video from Alexandre DaSilva, co-chair of the IHC 2025 Scientific Programme Committee! He warmly invites you to the first-ever Internationa Headache Congress in South America, where cutting-edge science meets the rich culture of #Brazil. Don’t miss it!
#IHC2025 #headache
Precision for migraine treatment: Are we there yet??
Our new study suggests that there are clinical and biological features which associate with, and might be useful for predicting, migraine treatment responses...
To find out more click the link below.
https://t.co/S0d29QjbHy
Proud to share new data on the short-term prognosis of minor ischemic stroke. With advancements in standard care, including DAPT and improved RF management, it's crucial to update figures and estimates. @mattfos89@RaffaeleOrnello@fededs00@Eleonor32576320
Boom! Cerebrospinal fluid (CSF) flow extends to peripheral nerves. Alexander Ligocki, Ed Scott and colleagues @UF@UFHealth blow our minds. New paper @ScienceAdvances. What will we call it now? Cerebro-spinal-nerve fluid (CSNF)? or maybe brain-spinal-nerve fluid (BSN)? Just when you think you have a few ground truths of the brain and nervous system, you are humbled again.
Key Points:
- The authors point out that dogma holds that cerebrospinal fluid is responsible for 'maintaining brain homeostasis through nutrient delivery and waste removal for only the central nervous system.'
- They show extensive CSF flow throughout the peripheral nervous system.
- They traced multimodal 1.9-nanometer gold nanoparticles.
- These nanoparticles were roughly the size of CSF circulating proteins.
- They squirted them into the lateral cerebral ventricle.
-They showed incredibly that the particles transitioned from central to peripheral nervous systems at root attachments and transition zones.
- They showed the particles could make it all the way to the axoplasm of distal peripheral nerves.
- Bigger 15-nanometer gold particles were not able to make the journey.
My take: We know that the nervous system does not contain the more traditional lymphatics and has a force field called the blood brain barrier. We know that CSF delivers nutrients and removes waste from the brain and central nervous system. Our previous ground truth was established by studies using dye tracers. Using small gold nanoparticles these authors 'tore down the dogma.' So the real question is whether it is time for a name change? Cerebrospinal fluid (CSF) or cerebro-spinal-nerve fluid (CSNF)? or maybe brain-spinal-nerve fluid (BSN)? Thoughts? Sartor resartus – the tailor re-tailored our view on this important aspect of neuroscience. BRAVO!
https://t.co/63yeOGTaru #parkinson #CSF #cerebrospinal #Alzheimers
NeuroImage: Angiostrongylus Pachymeningitis and Encephalitis With Extensive Parenchymal Involvement and Lack of CSF Eosinophilia https://t.co/emfjJ8HG80
#NeuroTwitter
Basal ganglia ischemic stroke is a rare but known complication of minor head trauma in young children. Learn more in this Teaching NeuroImage article: https://t.co/tstTiVL4RU
#NeurologyRF
Al-Khazali et al. show that individuals with migraine experience more problems related to neck pain compared to those with tension-type headache and healthy individuals without headache.
https://t.co/H18A4v4X9Z
#headache#migraine
why we should not stop anti-CGRP prophylactic treatment for migraine for regulatory reasons - re-administration has less effectiveness of the treatment causing unnecessary suffering for our patients, https://t.co/6vaqzp29kr
Cerebrospinal fluid links the brain and peripheral sensory system and drives headache in migraine with aura! We’re excited to share our newest article just published today in @ScienceMagazine . Please read along:
https://t.co/ab3HuaTpYe