Rupendra SHRESTHA, PHD

Retina Regeneration, iPSC/ESC, Organoids, CRISPR, Genetics|| Daughter’s Dad, Husband||

[Rupendra SHRESTHA, PHD @rdshrestha88]

I am pleased to share that I am honored with a @FightForSightNY postdoctoral grant of $22,500. I am working on modeling CRB1-associated retinal dystrophies using CRISPR/Cas9 engineered hESC and retinal organoids.
@EinsteinMed @epa_einstein #FFS2022 #RetinalOrganoids #StemCells

[Rupendra SHRESTHA, PHD @rdshrestha88]

Our recent article in the @wileyinresearch Journal of Nanotechnology highlights citrus peel–derived PEGylated carbon quantum dots and their potential applications in bioimaging and nanomedicine. @nirinepal @chettinad_univ
https://t.co/rn1zt7NvL8

[Rupendra SHRESTHA, PHD @rdshrestha88]

📢Our latest review in @Wiley_CancerRep explored the emerging role of FMT in enhancing immunotherapy & restoring gut homeostasis, though its clinical integration is currently limited by significant challenges. @nirinepal @chettinad_univ @gulfmedicaluniv https://t.co/kljQyhDFHw

[Rupendra SHRESTHA, PHD @rdshrestha88]

📢Our latest review in #MicrobiologyOpen explored Guillain–Barré syndrome, highlighting Campylobacter jejuni as the primary trigger, and also underscoring the silent role of Haemophilus influenzae. #GuillainBarreSyndrome @nirinepal @chettinad_univ
https://t.co/xD8FOPo560

[Rupendra SHRESTHA, PHD @rdshrestha88]

📢Our latest study in the @Wiley Journal of Cellular and Molecular Medicine showed Liposome-Encapsulated Melatonin is a promising therapeutic agent for reducing Amx-induced neurotoxicity in zebrafish #melatonin #Neurotoxicity @nirinepal @chettinad_univ https://t.co/SCNvnA5SNH

[Swasthya Khabar @Swasthyakhabar]

जलेका संरचना-सामग्री व्यवस्थापनका सम्भावित जोखिम, कदम र सुझाव https://t.co/I9aNxEfZn4

[Rupendra SHRESTHA, PHD @rdshrestha88]

📢Our latest review in @MedComm_MC explores how EMT drives cancer progression, metastasis, and resistance to radiotherapy, and highlights emerging therapeutic strategies to overcome these challenges.@nirinepal @chettinad_univ
#Cancer #CancerTherapy #RT
https://t.co/iwDCzOilnZ

[Rupendra SHRESTHA, PHD @rdshrestha88]

📢 Our latest publication in @SpringerNature Biochemical Genetics spotlights APOE4, ACE2, TMPRSS2, and OAS1 as key genes that link COVID-19 and Alzheimer’s disease via shared pathway. @nirinepal @chettinad_univ
🔗 https://t.co/QCyudqxvW7
#SARSCoV2 #COVID19 #Alzheimers

[NIRI @nirinepal]

🌐 Discover. Discuss. Drive Change.

Join us for a symposium where experts from diverse fields present their work on shaping the future of healthcare, education & research in Nepal.

🧠 Bold ideas. Practical insights.
📝 Register now: https://t.co/dhJpfORzQp

[Rupendra SHRESTHA, PHD @rdshrestha88]

Our latest study in the #Wiley Journal of Cellular and Molecular Medicine highlights miR-542-3p as a potential biomarker and therapeutic target for #HCC, promising for early detection and treatment. #Biomarkers #miRNA @nirinepal @chettinad_univ
📄https://t.co/2Yx9xjeze5

[Rupendra SHRESTHA, PHD @rdshrestha88]

Our recent review in "Molecular Nutrition & Food Research" explored how Bifidobacterium enhances colorectal cancer treatment by boosting gut immunity and reducing chemotherapy toxicity. @nirinepal #Bifidobacterium #colorectalcancer
Read here: https://t.co/hoxkrZ940K

[Infectious Microbes & Diseases @Journal_IMD]

Early Access
Authors explored the potential of phytochemicals, such as apigenin, berberine, curcumin, etc., for treatment of the liver conditions NAFLD, ALD and HCC, and discussed significant associations between phytochemicals and COVID-19.
https://t.co/9timT9sdiL

[Keith Siau @drkeithsiau]

Today I learnt that there are 3 different types of hunger

📸: https://t.co/a1fLJl9Egh

[Rupendra SHRESTHA, PHD @rdshrestha88]

Our recent review titled "Radiation Therapy-Induced Normal Tissue Damage: Involvement of EMT Pathways and Role of FLASH-RT in Reducing Toxicities" has been published in Radiation and Environmental Biophysics. @nirinepal @chettinad_univ
Check it out! https://t.co/07OGk0qkNd

[Rupendra SHRESTHA, PHD @rdshrestha88]

Our latest study, published in @PLOSONE, demonstrated that Six3 and Six6 control critical pathways that influence the development of ciliary margin cells and retinal neurons. @PLOS @EinsteinMed
#scRNAseq #Neurogenesis #EyeMorphogenesis
https://t.co/WkvGGgeNBr

[Meyer Lab @MeyerLab]

Now hiring postdocs and staff scientists! Come join our dynamic group focused on the development of stem cell models for studies of neurodegeneration, neuron/glia interactions, and neuroinflammation. https://t.co/9PuNj12HQM

[Rupendra SHRESTHA, PHD @rdshrestha88]

I am proud to be a part of the Nexus Institute of Research and Innovation (NIRI) Nepal, where we bring together experts from diverse backgrounds to drive scientific progress and innovation, contributing to the growth of science and research in Nepal. #NIRINepal

[NIRI @nirinepal]

Welcome to NIRI Dr. Shrestha.
Dr. Shrestha is a dedicated research scientist specializing in human pluripotent stem cell research, retinal differentiation, and gene editing with CRISPR/Cas9.

@rdshrestha88

#NIRINepal

[Rupendra SHRESTHA, PHD @rdshrestha88]

Exciting PhD research by #Kevin from @mku_official is now available on #MOLE. We analyzed the development and assessed the Mammalian Linear Expression System (MLES), emphasizing its improved transfection efficiency in both in vitro and in vivo. Link: https://t.co/Tllyw7LX6H

[Rupendra SHRESTHA, PHD @rdshrestha88]

We are excited to share our article on the use of eltrombopag for angiogenesis and vasculature formation of endothelial lineages derived from MSCs, as well as for protecting MSCs against radiation damage. @plateletjournal @AnalyticaAnka @chettinad_univ
https://t.co/hGCUt3io4P

[Rupendra SHRESTHA, PHD @rdshrestha88]

We are excited to share our research article on the use of injectable CBG hydrogel to encapsulate secretome-enriched MSCs, which were then differentiated into neuronal cells and transplanted to repair SCI in rats. @AnalyticaAnka @chettinad_univ
Link: https://t.co/AFMSW99Yjo

[Rupendra SHRESTHA, PHD @rdshrestha88]

We are pleased to share our latest article on how sulforaphane can modulate the NRF2-mediated PI3/AKT/mTOR pathway in arecoline-induced fibrosis in human gingival fibroblasts. #BrazilianDentalScience @gulfmedicaluniv Link:https://t.co/1JllGx8A1E