Matej Drev

Immersed in physical AI as COO at Viaduct. Passionate about health and longevity. Economist. Classical liberal. Personal opinions only.

[Samo Burja @SamoBurja]

Eastern Europe speedrunning the mistakes of Western Europe.

[euan ashley @euanashley]

Well, today seemed like as good a moment as any—while I was unpacking from vacation—to have Claude analyze my genome. This is not a trivial problem given my variant call file is over a decade old. But that also provides some nice challenges wrt file formats and ref calls.

[Matej Drev @realmatejdrev]

@PPLElectric your website and texts state you will restore power to 17055 by Tue, 7/7, 11:00PM (i.e., in 3 days). Is that a placeholder or your actual intention?

[Gad Saad @GadSaad]

He is an affront to the spirit of the United States. You’ve let in a deeply venomous snake.

[Bryan Johnson @bryan_johnson]

People are sleeping on how fast solving death becomes humanity's focus.

[Matej Drev @realmatejdrev]

America is an extraordinary country: vital, restless, ambitious, and full of people trying to make their communities and the world better. I’m proud to be a citizen of a nation still grounded in free speech, markets, and the resolve to defend itself. Happy 250, America! 🇺🇲🇺🇲🇺🇲

[Ron DeSantis @RonDeSantis]

250 years ago, on July 2nd, 1776, the Second Continental Congress voted to declare independence from Great Britain.

John Adams wrote to his wife the next day:

“The Second Day of July 1776, will be the most memorable Epocha, in the History of America.—I am apt to believe that it will be celebrated, by succeeding Generations, as the great anniversary Festival. It ought to be commemorated, as the Day of Deliverance by solemn Acts of Devotion to God Almighty. It ought to be solemnized with Pomp and Parade, with Shews, Games, Sports, Guns, Bells, Bonfires and Illuminations from one End of this Continent to the other from this Time forward forever more.”

Well, not quite.

On July 4th, the delegates adopted the Declaration of Independence — and that has been the day for celebrations ever since.

[Matej Drev @realmatejdrev]

According to the 4th turning, ekpyrosis is about to happen in the next few years.

Will it be internal (as proposed below) or external (a major external war)?

[InfantryDort @infantrydort]

Communists are putting the nation in the prisoner’s dilemma.

In this dilemma, the victory ALWAYS goes to the aggressor. The one who breaks the norms by crossing the line first.

So in the current construct, they will win.

There is a revolution unfolding in the country right now. Communism spreads like WILDFIRE when unchecked.

You can’t vote your way out of it once you vote it in. It takes full advantage of our tolerance and constitution until it kills us with both.

The only way to win the prisoner’s dilemma is to counterattack. Few are going to be comfortable with what that might look like. (Think Spanish Civil War).

We objectively KNOW what happens when this goes unchecked. 100+ million dead are the proof.

The question is, what are we willing to do to stop what we know is coming?

[Max Hodak @maxhodak_]

we joke about "infohazards" like roko's basilisk or the entertainment from infinite jest, but communism is in fact a real-world infohazard. they do actually exist.

[Garry Kasparov @Kasparov63]

…

[Nathan S. Cheng thinks you should work on aging. @realNathanCheng]

with the news of Anthropic getting into bio/pharma/aging remember that this was manifest destiny.

the end game for every technology company is immortality. @balajis

[Alesya @AlesyaMacWaters]

As we approach July 4th and America’s 250th anniversary, I have really been reflecting on how blessed I am to be a U.S. citizen.

I was born in Siberia, Russia, to Ukrainian parents who moved there for four years to do missionary work. My mom has told us stories of having no food and living through some of the hardest years of their lives.

People who have never lived under communism often speak about it like an idea on paper. It is not.

communism is a system where the government controls the economy, property, opportunity, and often the lives of its people. It strips people of the freedom to build, own, create, speak freely, worship freely, and determine their own future. It does not reward ambition. It does not create opportunity. It makes people dependent on a system that decides what they are allowed to have.

there was no version of “dream big and work hard” where we came from. There was survival.

my family was selected through a lottery to move to the United States. We came here with one suitcase for a family of six. A church sponsored us and someone gifted us an old chevy.

To us, that car may as well have been a Rolls-Royce.

we grew up incredibly poor. I have only a handful of baby pictures and very little from those early years. When I started school, I knew zero English. I made friends by teaching girls how to braid hair and braiding everyone’s hair in class.

But my parents worked relentlessly. They gave us opportunities they never had. They showed us what freedom actually looks like.

the American dream was never that everything would be handed to you.
It was that you could work hard, take responsibility for your life, build something of your own, create value, and become more than the circumstances you started in.

that is why I respect people who work hard. People who build companies, create jobs, solve problems, take risks, and make an impact on the world.

I know what it means to come from very little.

and I know that the ability to dream, build, own, work, worship, speak, and create freely is not something to take for granted.

I hope we never forget how rare that kind of freedom is.

(sitting on the Chevy and wearing a dress I was gifted 🥲)

[Igor Derenda @IDerenda]

Dr.@LahovnikMatej: Po 35 letih izgubljamo zagon. Visoke obremenitve dela dušijo napredek, nepremičnine so v kaosu, razvoj pa stagnira. Češka je že pred nami, Hrvaška nas zaradi boljšega poslovnega okolja hitro dohiteva. Nujno potrebujemo korenite reforme.👇https://t.co/iXLdvuzgwH

[Michael Eisenberg @mikeeisenberg]

Sitting at Pax Silica, I can’t escape the conclusion that the US over produced liberal arts majors with significant student debt and under produced electricians, Construction workers
And others needed for current AI boom. All the hyperscalers, memory companies (micron, Samsung etc) and fabs have emphasized the skilled labor shortage.

This was an incentives and leadership problem causing over production of under employable university liberal arts grads.

When you have debt laden university liberal arts grads (indoctrinated by endowed DEI chairs and other ideologies) who struggle to find employment or who look at electricians who studied in trade schools earning 4x more, you get demands for socialism and “Mamdanism”.

[Bad Hombre @Badhombre]

New Yorkers chose to vote themselves into communism two days after Colombians chose to vote themselves out of it. You can’t fix stupid.

[Matej Drev @realmatejdrev]

This is the only practical way. Hence why replacement research, engineering, product development, and business model innovation will be the most important area to play in the next decade.

[LindyMan @PaulSkallas]

He can have a great biomarkers, cardiovascular system and zero plaque, but his organs are still aging. You can't stop that.

He's going to surgically replace his organs later in his life. He doesn't tell you about that part. We're still in the diet and exercise phase.

He's going to implant a young man’s heart, a young man’s kidneys, a young man’s liver into his body to keep this experiment going.

[Matej Drev @realmatejdrev]

Wow.

[Dr. Rhonda Patrick @foundmyfitness]

Early-onset cancer rates have increased nearly 25% in the last 30 years.

Why?

Newer generations appear to be aging "biologically faster."

A larger age gap among recent generations is associated with a greater risk of lung, GI, and uterine cancers, independent of genetic risk.

[Chris Bakke @ChrisJBakke]

I fully agree that we should dismantle SpaceX, Tesla, Neuralink, Boring Co, etc to give a cohort of people free 2 year degrees in gender studies and humanities.

Talk about making the world a better place.

[Marc Porter Magee 🎓 @marcportermagee]

If you linger too long on any college content on Instagram this is what you feed ends up looking like

[Brian Armstrong @brian_armstrong]

Agree - everything in hard tech is more difficult than software (especially in bio where we barely understand how it works)

Arguably the best way to do a biotech company is:
1. make a billion dollars in software
2. self-fund the biotech (at least in part, to de-risk it)

If you don't have a software billionaire patron, the uncanny valley (series C crunch) can be brutal in bio.

It's still worth attempting hard things that can move society forward even if difficult tho. Arguably you have a responsibility to do so once you've made money in software.