The Rihel lab

Zebrafish lab @UCL. We study the genes & neurons that regulate sleep 🐟💤

[The Rihel lab @realRihellab]

As reigning Greater London Chess Club champion, Prof Rihel takes on 14 club players at once. Final score- 8 wins, 3 draws, and 3 losses against a tough group!

[The Rihel lab @realRihellab]

@anaclet_lab I think Estimation stats would do them wonders!

[The Rihel lab @realRihellab]

@LuciaScience @sleepdiplomat @LunsfordAvery Ah, yeah, I found it from my mind grapes: There was even an Op-Ed on this idea in the New York Times in 2013: https://t.co/SNPvXzo9r4

But I never hear much about this now, and certainly I don't work with kids nor followed this area closely.

[The Rihel lab @realRihellab]

@LuciaScience @sleepdiplomat @LunsfordAvery Yes, I realize ASD/ADHD patients have a high rate of sleep problems, and there is some evidence that sleep interventions can ameliorate eg ASD symptoms.

I was more asking on curiosity re: ideas in sleep dep/ADHD misdiagnosing, like this one: https://t.co/98uATXXwFj

[The Rihel lab @realRihellab]

@sleepdiplomat @LunsfordAvery Sorry if that’s in the video but as a rule I don’t watch videos here.

[The Rihel lab @realRihellab]

@sleepdiplomat @LunsfordAvery There were some papers years ago suggesting that kids with chronic sleep deprivation where getting diagnosed improperly as ADHD, and things like removing the tonsils in those cases fixed the apnea and sleep problems — and the ADHD like symptoms. What is the latest on that front?

[SWC @SWC_Neuro]

Applications now open! Join the SWC PhD Programme 2025

🧠 World-class training in systems neuroscience
💰 Fully-funded 4-year programme
💂 Based in London with close links to @GatsbyUCL

Learn more and apply by 11 Nov: https://t.co/8g0atYhP2g

#PhD #Neuroscience

[Don B. Arnold @Don_B_Arnold]

Check out our preprint on new recombinant tools for reversibly ablating excitatory and inhibitory synapses.

https://t.co/SPUvz4vwAw

Thanks to amazing first author @AidaBareghamyan and collaborators @RichKramerLab , Dave Chenoweth and Robert Campbell.

[Misha Ahrens @MishaAhrens]

Excited to post a new preprint, work by @T___Kawashima, @zq_wei and collaborators:

Voltage imaging reveals circuit computations in the raphe underlying serotonin-mediated motor vigor learning

https://t.co/IHzsx0z4AF

[The Rihel lab @realRihellab]

Confusing stuff. Influx isn't efflux (clearance). Is it less gets in during waking or simply more on net gets out? Also, per intro, more Abeta is *secreted* during sleep deprivation, so its accumulation says little about clearance. https://t.co/N58pDfc4xH

[Dr. Len Zon @leonard_zon]

Very happy to have Boston Children's Hospital cover our recent Science paper on macrophages quality assuring stem cells by sensing ROS (dooming) or endogenous viral elements (grooming). This discusses our future plans. https://t.co/tv9luKyyrZ

[Marcus Ghosh @MarcusGhosh]

I recently gave a talk on:

Nonlinearity and network topology in multimodal circuits.

Which you can watch here:
https://t.co/BpAdDS9tr3

[The Rihel lab @realRihellab]

Whoa!

[Luísa Tupinambá Jabbur (ʒabuʁ) @M_louisae]

Incredibly proud to share this work, almost 6 years in the making, out in @ScienceMagazine!!! 🎇

We've known for over a century that eukaryotes of all kinds anticipate the seasons (think: hibernation, flowering, reproduction), but what about bacteria?🦠
https://t.co/I9vw5ZTKbT

[The Rihel lab @realRihellab]

@YanivElkouby Given how much wasted time for teams on both ends of live fish shipments lately, even if someone else is footing the cost, I am likely to only share lines via sperm shipment in the future, tbh. It is so easy!

[The Rihel lab @realRihellab]

Zebrafish peeps: I understand after many conversations at the Kyoto meeting that not everyone is aware of the Room Temperature zebrafish sperm paper. In Vitro Storage of Functional Sperm at Room Temperature in Zebrafish and Medaka | Zebrafish (https://t.co/yDq3IhByHF)

[The Rihel lab @realRihellab]

@ardemp I have to scroll past a lot of crap to find the science posts here now. Really degraded quality.

[The Rihel lab @realRihellab]

I loved the website 1 million checkboxes. And now I am even more pleased to see what the nerds were doing with the site. Incredible! https://t.co/JiTDCLiadh

[The Rihel lab @realRihellab]

@MadS100tist It is a good point and we should keep track to see if anything obvious pops up.

[The Rihel lab @realRihellab]

@MadS100tist Good, cause that one shows there is no effect on methylation in the sperm when stored.... and when they go site by site in embryos at one stage, there are some differences in specific gene methylation, but is that very different than what you would get from 3 different dads?

[The Rihel lab @realRihellab]

@MadS100tist Changes made after the sperm itself is differentiated? Not epigenetic changes during spermatogenesis? any references?

[The Rihel lab @realRihellab]

@MadS100tist No, we haven't tested that yet. Would we expect it to have problems? Does sperm itself do a lot of epigenetics/provide anything other than DNA to the egg?