Workshop Spotlight: Cholesterol- and Triglycerides-Rich Remnants
Join experts Mie Balling and Patrick Rensen to explore remnant cholesterol's impact on ASCVD and its molecular mechanisms.
๐ Explore the workshop: https://t.co/CmWdB76pfM
#Atherosclerosis#EASCongress2026
Our new paper, "NK2R control of energy expenditure and feeding to treat metabolic diseases," is out today in @Nature.
Here we identify a single receptor that can both peripherally increase energy expenditure and centrally suppress appetite.
https://t.co/6Q8nG7wFOs
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Just online: Liver-targeted Angptl4 silencing attenuates hyperlipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice, our well-established model for human-like lipid metabolism and cardiometabolic diseases @LUMC_Leiden@Lipigon_Pharma https://t.co/K9rLz3T10O
It was a real pleasure to give a keynote on (pre)clinical studies on #brownadiposetissue#bat at the annual meeting of the Austrian Atherosclerosis Society. Thank you so much for the kind invite! @LUMC_Leiden
Pharmacologic inhibition of the immunoproteasome with ONX-0914 attenuates atherosclerosis, metabolic syndrome, and reduces white adipose tissue mass in mice @Rensen_Lab@FoksAmanda@mariedepuydt@JilldeMol
https://t.co/Q4p0YpMUSv
#CETP inhibition enhances bacterial clearance to reduce pneumoniae-associated mortality in APOE*3-Leiden.CETP mice, suggesting CETP inhibitors to be repurposed to prevent #sepsis-related mortality in humans! @LUMC_Leiden
https://t.co/jdX55x72bK
@CarlijnHoekx was awarded the Publication Prize 2023 of the Netherlands Association for the Study of Obesity at the #NASO spring meeting. Proud mentor! ๐๐ @LUMC_Leiden
@MilenaSchonke zoekt mannen en vrouwen met overgewicht en mogelijk leververvetting voor onderzoek naar het effect van trainen op de hoeveelheid vet in de lever. Scan de QR code voor meer informatie over deze studie! @LUMC_Leiden
CETP Inhibition may well have therapeutic applications beyond targeting ASCVD, including protection against septicemia. Certainly relevant, giving that the bulk of circulating #CETP derives from #macrophages! @LUMC_Leiden@NewAmsPharma https://t.co/DtVfJ5uvpN
Proud of @KooijmanSander who was awarded a Dekker Senior Scientist grant of the Dutch Heart Foundation to dive deeper into the #circadianrhythmn of #brownfat to reveal novel (chrono)therapeutic approaches to comBAT atherosclerotic #CVD! ๐๐ #batman@LUMC_Leiden
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@KooijmanSander just received a Dekker grant of the @Hartstichting to dive deeper in the #circardianrhythm of #brownfat to reveal (chrono)therapeutic handles for the reatment of #atherosclerosis. Proud mentor! ๐๐
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https://t.co/A9ko5ykN04
Highly recommended PhD position with a dedicated supervisor in Almerรญa, and with the opportunity to perform part of the research at @LUMC_Leiden! ๐๐