Gordon Rix

protein engineering with Rube Goldberg machines at Boston University

[Sergii Pochekailov @pochekailov]

Meanwhile, the Sergi Lab Supplies do not waste money on website design and are able to offer the same literally for 10x cheaper

[Sergii Pochekailov @pochekailov]

I have been selling magnetic racks and magnetic beads for several years now.

Magnetic racks are about 65% of sales.
Magnetic beads for DNA purification are only 9%.

I assume that you use the racks mainly for DNA purification.

Am I wrong? If not, is there something wrong with my beads? I would expect much more magnetic beads sales.

I would greatly appreciate to learn why you would not choose my beads. Price too high? Or too low? Too good to be true? You tested the sample of beads with NEB ladder and it didn't work? Something else?

[Chang Liu @chang_c_liu]

Happy to share the peer-reviewed and updated version of our work on OrthoRep-driven evolution of aaRSs for genetic code expansion with unnatural amino acids. Congrats to @yuichi_furuhata, a true master bioengineer, on leading this excellent work! https://t.co/2iYPAg0yq8

[Chang Liu @chang_c_liu]

In this work, we bring OrthoRep’s mutation rate up to 10^-4 substitutions per base, allowing us to durably hypermutate and evolve chosen genes in vivo at 1-million times the genomic mutation rate of the host yeast cell. What does this afford? https://t.co/5Cgn39jpax

[Jason "boundless delight " Williams @JasonWilliamsNY]

Let me show you how to DOUBLE your sequence throughput and read length using this one weird trick. @nanopore HATES this.

[Elliot Hershberg @ElliotHershberg]

New experiment this week for COB...

I'm releasing a new software tool + an accompanying essay 🧬

Learn more about *The Interactive Mutation Browser*

[Oklahoma Department of Wildlife Conservation @OKWildlifeDept]

WE👏 ARE👏AWARE👏THE👏LOGO👏LOOKS👏LIKE👏A👏BEARDED👏DUDE👏IN👏AN👏ORANGE👏HAT👏

—YOU👏DO👏NOT👏NEED👏TO👏KEEP👏POINTING👏THAT👏OUT👏EVERY👏SINGLE👏DAY👏

[Eliezer Yudkowsky ⏹️ @ESYudkowsky]

Never forget: the people telling you that fedoras don't look awesome, are people who think you don't deserve to look that good.

[Jake Wintermute 🧬/acc @SynBio1]

ML for bio is fed all the DNA sequences of nature and makes a beautiful glowing enzyme

ML for tech is fed all the content from the internet and makes a toxic psycho chatbot

As you choose your next career moves remember that you have to live in the world you build

[Jeremy England @lifelikephysics]

https://t.co/1PAKO6V75q

[B is @[email protected] @[email protected] @thuronyi]

@spleonard1 Definitely don't put the entire plate including the polystyrene into a blender with some LB, homogenize, and then filter the paste through a Buchner funnel and culture the filtrate... unless...?

[Coolmath Games @TheRealCoolmath]

🍞 >>>>>>>

[translated cats @TranslatedCats]

And then the truth came out when I bought her a new toy.

[stefan @wasserstein_rao]

I'm excited to announce the release of our hardware-agnostic interface to liquid-handling robots, PyLabRobot. PyLabRobot provides a common language for communicating with different types of robots in Python.

Github repo: https://t.co/CZQ5jC1jLO

https://t.co/K5IvsLYKNt

[Gordon Rix @rix_gordon]

@Grippingfoods those tomatoes are not being gripped very forcefully

[Gordon Rix @rix_gordon]

@pdhsu Definitely agree with everyone saying it varies a lot, but just to add a concrete example: from a recent experiment I got 2.5 million reads for a 3.4 kb amplicon with the first use of an R10.4 flow cell using the LSK-112 kit

[Nature Reviews Methods Primers @MethodsPrimers]

New this week! In vivo continuous evolution takes advantage of cycles of rapid mutation, amplification and selection inside living cells @cnb_csic @CSIC @Beatriz_Al_Go @lafdez_synbio @chang_c_liu @haiqi_chen @UTSWScience @francesarnold @zerlinia

https://t.co/wXxdiwXlvE

[Gordon Rix @rix_gordon]

@chorye yes! probably won't be me, but I'll certainly be shilling the idea to every new lab recruit 😁

[Gordon Rix @rix_gordon]

this is INCREDIBLE. Everyone who didn't get me a Christmas gift this year, it's not too late...

[Emma J Chory @chorye]

In light of the great consumables shortage of 2021, we've also completely revamped the method to recycle, sterilize and reuse all robotic tips. The current method uses ~ 5 boxes of tips per day. 6/n....

[Chang Liu @chang_c_liu]

Today, we present peCHYRON, a DNA recorder that propagates an unending chain of insertions. Each link contains a randomizable 3-bp “signature” sequence that serves to record a cellular event. The result: temporally-resolved cellular event recording! 1/12 https://t.co/9CaUigKDIZ