Robert Dick Lab

Investigating the mechanisms of retrovirus budding and maturation using a combination of biochemistry, cell biology, and cryo-EM starting at @EmoryMedicine soon

[John Briggs @BriggsGroup]

Mature #HIV-1 contains >2000 copies of “spacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from @MargotRiggi :

[EMDB - EMPIAR @EBI @EMDB_EMPIAR]

https://t.co/9V54KQNuBp is the raw data of the "Defective HIV-1 capsid lattice assembled on 30-nm liposome scaffolds in the absence of assembly cofactor IP6". Published @PNASNews (https://t.co/wrA7sKUEZN) by the @BriggsGroup and @RobDickLab @MPI_Biochem and @Cornell. #EMPIAR

[Robert Dick Lab @RobDickLab]

The companion paper from James Stacey and John Briggs is now online as well https://t.co/KgOqLO5FK2 Please also check out the excellent work by Randall Schirra, Barbie Ganser-Pornillos and Owen Pornillos https://t.co/HErCaI2cWU

[Robert Dick Lab @RobDickLab]

We're so pleased to share Dr. Highland's #CryoEM work on HIV-1. @altos_labs is lucky to have recruited such a talented scientist. Wishing her the best.

[Carolyn Highland @CarolynHighland]

Our latest paper describing our use of single particle #cryoEM to examine the HIV-1 capsid is out now in @PNAS! Here, we determined structures of continuous regions of the capsid lattice. (1/8)
@RobDickLab

[Robert Dick Lab @RobDickLab]

Thrilled to be joining Emory U as an Assist Prof at the Center of ViroScience and Cure! Excited to contribute to such a world-class drug discovery/basic science group. Thank you for the warm welcome! 👍❄️🔬 🦠

[Sarafianos Lab @SarafianosLab]

Great news: Rob Dick @RobDickLab is making the big move from Cornell to Emory U, as an Assist Prof at our Center of ViroScience and Cure!!! He'll further strengthen a world class drug discovery/basic science group that recently also recruited @michailidis_lab from Rockefeller U👍

[Fatemeh @Lady_in_Lab]

What is more fun than studying viral assembly, release and maturation here @RobDickLab @Cornell doi:10.1038/nrmicro3490

[Ryan Feathers @FeathersRyan]

If you're applying to PhD programs in the life sciences check out my personal statement writing guide! Special shout-out to the faculty that contributed some great advice! #gradschool #PhD
https://t.co/i4hN5Yt5Qe

[The B-HIVE Center @BHIVE_Center]

The B-HIVE Center is up and running, building on 10 years of work of the HIVE Center! 31 labs working together to reveal the structure and function of HIV-1 and its interactions with cellular host factors. For more information, see https://t.co/dqkqitKHyC

[Robert Dick Lab @RobDickLab]

@Guillawme If I'm understanding the question correctly, I believe this is normally handled by serialEM for us. Motioncorr on the fly and save as a stack for each tilt series. The command to do this with IMOD should look something like: newstack TS01_frame_0?.mrc TS01_stack.mrc.

[Robert Dick Lab @RobDickLab]

A successful week at the Cold Spring Harbor Laboratory Retroviruses conference! Two posters and two talks were presented by the Rob Dick Lab #CSHLRetro

[Robert Dick Lab @RobDickLab]

Our lab website is live! Check it out for details about our research, lab members, publications, and more https://t.co/OwbMFfP9NA

[Robert Dick Lab @RobDickLab]

Our very first print with our @ff3dprinters Guider IIs - Iron Throne Benchy! Next, we'll test the integrity of different filaments at cryogenic temperatures #3DBenchy

[Robert Dick Lab @RobDickLab]

Happy birthday to our one and only Rob Dick! Thanks for all that you do! 🎂
- The Lab

[Robert Dick Lab @RobDickLab]

Inositol Phosphates and Retroviral Assembly: A Cellular Perspective https://t.co/TWnm3LlAQ7 #mdpiviruses via @VirusesMDPI

[Robert Dick Lab @RobDickLab]

Review article now available! https://t.co/i28m22Ct9F

[Robert Dick Lab @RobDickLab]

@SchurLab @EMBO_YIP @ISTAustria Congratulations Florian!

[Ryan Feathers @FeathersRyan]

Thanks @AlisterBurt for the starfile tool! Had fun using it to play with some Relion 4 data!

[Robert Dick Lab @RobDickLab]

Our work on Rous sarcoma virus is now online @NatureComms. A continuation of the IP6 story with RSV structures! It was a joy to work with everyone. Special thanks to Florian Schur and Martin Obr @SchurLab. https://t.co/CvKS4FKzbA

[Robert Dick Lab @RobDickLab]

I'm lucky to collaborate with such excellent scientists and people. Check out our preprint!