Have you wondered how a decades-old oocyte can give rise to a new embryo while other cells in the body age? Our study @Nature, spearheaded by @AidaRoNu, uncovers the mechanism that allows early #oocytes to maintain ROS-free #mitochondria https://t.co/eVQfeRWmVq🧵
Enjoyed this great NYT article on APOL1, its association with kidney disease in African Americans and the related drug development efforts. It's story telling time. Let's dive into the story of APOL1 from discovery to therapeutics. 🧵
https://t.co/jj8iTAjQ4N
Over the last 15 years, the gender balance of A-level Physics candidates in the UK has remained practically unchanged. In contrast, in Finland the percentage of females has increased from 17.8% in 2006 to 44.8% in 2021. It might be worth looking at how this change was achieved.
Incredibly excited to share our paper ‘Somatic mutation rates scale with lifespan across mammals’ now published @nature.
https://t.co/a68IkkTt33
An illustrated & updated tweetorial… [1/24]
The single most undervalued fact of linear algebra: matrices are graphs, and graphs are matrices.
Encoding matrices as graphs is a cheat code, making complex behavior simple to study.
Let me show you how!
Membranous #nephropathy is characterized by thickened glomerular capillary walls due to immune complex deposition at and within the basement membrane https://t.co/XHnWXDIgLo
Vascular congestion of the renal medulla is a hallmark finding in patients with ischemic acute tubular necrosis. Findings from this rat model study suggest that medullary vascular congestion is a cause rather than a consequence of tubular injury https://t.co/Ws7umLy9R0
New Perspectives online! Robert Hunter @renalrob, Neeraj Dhaun @EdinUniCVS and Matt Bailey @edinburgh_renal discuss the impact of excessive #salt intake on human health https://t.co/mNppr9KdBb
New Perspectives online! Robert Hunter @renalrob, Neeraj Dhaun @EdinUniCVS and Matt Bailey @edinburgh_renal discuss the impact of excessive #salt intake on human health https://t.co/mNppr9KdBb
Kidney disease is a known risk factor for poor outcome of COVID-19 and other serious infections. This Review explores the epidemiology of SIDKD and aspects of the abnormal immunophenotype of patients with kidney disease https://t.co/NfP9jtwM1Z
@StefanieSteige6@hjanders_hans
📢 The Wow Number: 850 million people in the world have kidney disease.
This figure results from a joint survey by the leading kidney societies: @ASNKidney, @ERAkidney, and @ISNkidneycare
Read the survey here: https://t.co/PtbsKGC1Gh
#850challenge#kidneycare
BREAKING NEWS:
The 2021 #NobelPrize in Physiology or Medicine has been awarded jointly to David Julius and Ardem Patapoutian “for their discoveries of receptors for temperature and touch.”
Age-associated changes to podocytes adversely affect kidney health. This Review discusses the molecular and cellular mechanisms underlying podocyte aging and approaches to mitigate progressive damage to podocytes https://t.co/jCzLKFtWao
People who have recovered from covid-19 have a greater risk of kidney disease, even if they only experienced mild to moderate covid-19 symptoms and were not admitted to hospital https://t.co/TbZUHWU7xT
1.Our lab’s newest paper now online at @CurrentBiology explores a fundamental question in stem cell biology. How do 100s or 1000s of stem cells, dispersed throughout an organ,coordinate their behaviour to ensure the right # of differentiated cells are made https://t.co/QALuRBSIvw
By 2040, chronic kidney disease is estimated to become the 5th leading cause of death globally.
@kamkalantar and colleagues provide a Seminar on the disease and discuss kidney function-preserving lifestyle, dietary, and pharmacological strategies. https://t.co/f2N52Flbez
CRISPR systems are quite diverse, including some, like CRISPR-Cas13, which target RNA. @soumya_kannan12 & @altaetran found tiny versions of Cas13b (Cas13bt) that can be used to create RNA editors small enough to fit into a single AAV for in vivo delivery. https://t.co/dvnC8l29uY