Breaking tradition can improve patient outcomes. In novel-known combinations where the novel drug is unlikely to work well alone, prolonged exposure to monotherapy in dose escalation is not patient-centric. This alternative FDA-approved phase I design poses a potential solution.
Pleased to present these new data at ASCO #ASCO23 and simultaneous publication in JCO.
https://t.co/3lSj69xFM4
Here, we tested combination of encorafenib + binimetinib in patients metastatic BRAF V600E mutant NSCLC 1/
I’m heartbroken and angry to see another family, another community hurting due to police brutality. I stand with my hometown and the people of Memphis as we demand justice and accountability. #JusticeforTyreNichols
We're so proud that MSK has the largest institutional representation in the Fellows of the @AACR Academy class of 2022! Please RT and congratulate Drs. Luis Diaz, Thomas Kelly, Neal Rosen, Nikola Pavletich, and Alexander Rudensky. 🎉
https://t.co/wl8o7ucshy
In a historic first, Dr. Valerie Rusch will be the first woman to be honored by the AATS Foundation Honoring Our Mentors program with the establishment of a mentored career development award in her name. Show your support for this valuable program: https://t.co/1VxjLGaMer
11 years ago I thought none of the following were possible: 10 years ago I came out to family and friends 🌈. 8 years ago I met my wife at Boston pride thanks to @CohenProf. 2 years later he legally married us. Today we celebrated #NYCPride with our 3 kids. #Pride2021
My mentor, my sponsor, the best drug developer in the world and my friend from 16 years died today.
I am where I am because of him and I am who I am because of him. I have no words.
Had a late night visit to @sloan_kettering’s Zuckerman building (more on that later) & saw a familiar #healthcarehero staring back at me: @alexdrilon our Early Drug Development Chief - making major inroads in targeted therapies based on the science
Ending this mess of a year feeling hopeful. Took care of wonderful patients and this. Grateful for the science and the people who got it done. Bring it on 2021. #maskup#FauciOuchie#mskcc
MET IHC is back from the dead! We wrote it off as a biomarker, but pl see latest study from our group lead by @alexdrilon & @RobinGuo5 which found MET expression to predict TKI response in MET Ex 14-altered NSCLC. Twists & turns of the ever-evolving NSCLC biomarker story!
With T-7, I need it send a happy one. There is nothing like one of your favorite fellows @RobinGuo5 dressing up with you in clinic to make a few patients and their family members smile ... Halloween 2019.... only thing better is to have him to come on faculty at MSK !!
From Phase 1 study to FDA approval in < 3 years & NEJM paper. Such a delight to work with a global team of amazing investigators, from 65 centers, in 12 countries ➡️Efficacy of Selpercatinib in RET Fusion–Positive Non–Small-Cell #lungcancer@NEJM https://t.co/NSqxPTzRE1
Wonderful team effort from many people around the world. I want to take a second to especially thank our patients and families without whom we could not have accomplished this. We are in your debt. Shout out to the RET Renegades! https://t.co/lgwSsxYDEz