Rob Wüst

Associate Professor Muscle Metabolism at Vrije University Amsterdam, Netherlands. Interested in skeletal muscle function in health and disease

[Rob Wüst @RobWust]

🧵 THREAD: Skeletal Muscle Alterations in Long COVID and ME/CFS
1/ 💡 Study Overview
We studied whether skeletal muscle changes in Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) patients are due to inactivity or distinct pathological processes.

[Rob Wüst @RobWust]

https://t.co/Mk2o9zj3by Complete scientific program of the upcoming @ISLCPAIS conference in Amsterdam is now online! Great opportunity to connect with colleagues and share knowledge on Post-Acute Infection Syndromes. Late-breaking abstracts open soon, register now!

[Long COVID Nederland @LongCovidNL]

🎬 Terugkijktip: "Het zit niet tussen de oren, het zit in de spieren" – RTL 4 Knappe Koppen, seizoen 4, aflevering 1

Er bestaat nog steeds veel onduidelijkheid over long covid, óók onder medische professionals. Het RTL 4-programma Knappe Koppen volgt bewegingswetenschapper dr. @RobWust aan de VU, waar hij onderzoek doet naar het effect van long covid op spieren. Het is een van de onderzoeken die wordt gesteund door @StLongCOVID.

🧬 Uit het onderzoek blijkt dat long covid géén psychologisch probleem is. Rob Wüst ontdekte met zijn team dat op spiercelniveau de mitochondriën (ook wel de energiefabriekjes van de cellen) minder goed functioneren en minder energie produceren. Dit verklaart deels de vermoeidheid waar mensen met long covid, maar ook met ME, mee te maken krijgen.

👥 Ook vertelt Knappe Koppen het verhaal van twee van de 450.000 mensen in Nederland die nooit zijn hersteld van covid: Lauren (28) en Ly-Ann (18) geven een inkijkje in hun dagelijks leven. Ze vertellen openhartig waar ze tegenaan lopen, hoe ze omgaan met PEM en de zeer ernstige vermoeidheid, en welke enorme impact long covid heeft op henzelf en hun naasten. "Mijn grootste angst is dat ik in het donker lig."

🚀 Het baanbrekende resultaat van de VU was weliswaar een grote doorbraak, maar ook slechts een eerste stap. Verder biomedisch onderzoek is nodig om deze inzichten te vertalen naar niet alleen meer kennis over de ziekte, maar ook naar betere diagnostiek, medicatie en behandelingen.

🩵 Doneer daarom nu en help Stichting Long Covid deze en andere essentiële onderzoeken te steunen.

⏳ Elke dag telt.

🔗 Link naar de aflevering: https://t.co/0tvvcMILEs (seizoen 4, aflevering 1).

#LongCovid #StichtingLongCovid #Kijktip #Onderzoek #RTL4

[Rob Wüst @RobWust]

@cstroeckw NASA studies do this. Participants in LC&ME studies typically do a lot of relaxing before they come for research visits

[Rob Wüst @RobWust]

@cstroeckw This is interesting to think about indeed. I don’t know this would make everyone at baseline roughly the same. In our work, we plan visits long multiple weeks and we typically see that participants “prepare” by taking rest beforehand. NASA studies are extremely expensive.

[Matthew S. Alexander @Matt_Muscle_Guy]

New @CommsBio paper: Myofiber-specific knockout of TGF-β type I receptors in mice concurrently drives muscle hypertrophy, oxidative metabolism, and absolute force. https://t.co/TEvXysXSh3

[Rob Wüst @RobWust]

@HeWaHippo Great stuff, congrats! Looking forward to read!

[Rob Wüst @RobWust]

@ISLCPAIS @CiaraGlenville you can bring a mini-drum😃

[David M. Sabatini @DMSabatini]

For a variety of reasons, we’ve been quantitating many western blots & radioactive protein gels so made this app for doing so as unhappy with what is available. Can quickly quantitate gels/blots & make simple graphs from the data. Instruction tab in app.
https://t.co/fdx1stYA8f

[TeamDerave @TeamDerave]

🚨 We are hiring a PhD and a Post-doctoral assistant at the Ghent Muscle Lab (Ghent University, Belgium) with strong interest in muscle & exercise physiology, bioinformatics, metabolomics or molecular biology.
Apply by June 30.
https://t.co/wJ6JPReFxe
https://t.co/bXdt0n5n06

[Andrea Pilotto @andreapil8]

Wonderful 2026 ACSM conference.
Great science, great friends!

It was awesome to share the stage with such distinguished scientists @RobWust and Gwenael Layec.
@ACSMNews

[Rob Wüst @RobWust]

@mdonnino @ISLCPAIS Yes we will open a late breaking! Would you present any results of the trial?

[Rob Wüst @RobWust]

Our long covid conference in Amsterdam @ISLCPAIS in August is attracting attention, with around 160 abstracts and session speakers, so far! You can still submit and register! https://t.co/D5kDe6jN5g for more information

[International Biochemistry of Exercise Conference @BiochemExercise]

#IBEC2028

[International Biochemistry of Exercise Conference @BiochemExercise]

Overjoyed to have our IBEC Honor Award lecture being delivered by Dr. Mark Febbraio!!!

[Rob Wüst @RobWust]

@mackinprof @DebevecTadej Oh I only wished I had seen this 3 hrs earlier on the plane! It would have made my 10hr flight! (Back home is a night flight - i guess it’s not a boring podcast right🙄?)

[Rob Wüst @RobWust]

@JanetDafoe American college of sports medicine. Two presentations about PEM and exercise in long covid / ME. They are updating their sports medicine guidelines if I am not mistaken

[Rob Wüst @RobWust]

@themupsmuppet @JanetDafoe Haha. Would have been nice to schmooze 160 abstract presentations 🙄😀

[Rob Wüst @RobWust]

@JanetDafoe I am actually talking at a large American conference but my students will be there:)

[Rob Wüst @RobWust]

ABSTRACT DEADLINE EXTENDED UNTIL 28TH MAY!
We have received over 125 abstracts related to #LongCOVID and Post-Acute Infection Syndromes (#PAIS) for the ISLC-PAIS Conference 2026 (26-29 August) in Amsterdam. Register at https://t.co/SHD33RV9dR for the largest PAIS conference?!