Roopali Khanna

Integrated Ph.D. student @SamratLabMohali @IiserMohali

[Sayanta Mahapatra @DrSMahapatra]

A novel recipe to obtain ultra-pure full-length Tau for co-factor-free/induced aggregation for high-res studies. Thanks @WalczakMAA, co-lead Ruiheng, and co-authors

[Samrat Mukhopadhyay @SamratLabMohali]

Happy to share our latest preprint.
https://t.co/wBnqL7f81Y

[Samrat Mukhopadhyay @SamratLabMohali]

Dr. Arpita Singh @Arpita195 (National Postdoctoral Fellow in our lab) is attending an EMBO Symposium on "Cellular Mechanisms Driven by Phase Separation" starting today at EMBL Heidelberg, Germany. She will present her new results on nucleolar condensates.

https://t.co/PNySyfXcP0

[Swastik PG @PgSwastik]

Thrilled to share my first first-author preprint from my PhD! 🎉 We asked,
can a low cost, FDA-approved α1-AR blocker reverse Alzheimer's disease at the molecular level?
In the TgF344-AD rat model: YES- and the effect is strikingly sex-dependent.
bioRxiv: https://t.co/42hamLEzLL

[Catalyst @ayusmansen]

Great work by @ShandilyaEkta and @Xiaotianlxt. From passive, receptor-based delivery to dynamic, energy-responsive targeting. Chemotaxis of ATPase-Powered Nanoparticles up Extra- and Intracellular ATP Gradients | Nano Letters https://t.co/slBpp0qGBr

[Samrat Mukhopadhyay @SamratLabMohali]

In a collaborative study led by @Krishanpal_K published in @CellReports, we show that phase separation of Plasmodium falciparum Heterochromatin Protein 1 is essential for heterochromatin formation and malaria virulence gene control. Congrats to the team!!
https://t.co/08c5deW04i

[Samrat Mukhopadhyay @SamratLabMohali]

To all our dear friends, colleagues, students, staff, collaborators, supporters, well-wishers, and academic associates:

Wish you and your family a very happy, prosperous, productive, peaceful, joyous, and healthy New Year 2026.

- The Mukhopadhyay Lab

[DA_LAB IISER Mohali @DA_catalysisLab]

Catch our latest publication in @NatureComms where Indigo, a classic dye is reimagined as an extreme photocatalyst with a very broad excited state redox window @DCS_IISERMOHALI. Huge thanks to @dm_lab for his initial support.
https://t.co/HBU3GUQwej

[Miao Yu @MiaoooYu]

How liquid-like is the nuclear pore barrier?🍝𖣐
Our new preprint shows that FG-NUPs exhibit nanosecond-scale, liquid-like mobility in living cells. 💧⚡O-GlcNAcylation and an importin-β gradient keep the FG network liquid-like, reconciling nuclear pore complex models.

[Santosh Satbhai @santosh7bhai]

Proud to share our new study nw online in @NewPhyt!
We showed dat the PEP2–PEPR2 signaling module plays a key role in Fe-deficiency responses and root growth in Arabidopsis. Gr8ful to @DBTIndia for the support. @DBS_IISERM @IiserMohali https://t.co/ZDOJZDBizv @sbslab_IISERM

[Mily Bhattacharya @MilyBhLab]

Happy to share our latest paper published in PCCP (Physical Chemistry Chemical Physics) @PCCP @RoySocChem. Congratulations to my PhD student, @Jaspreet_Tiet @TIETofficial. Thanks to ANRF-POWER and MoE-STARS for supporting our research.

Here's the link:
https://t.co/MJVkfGH8uM

[Subhabrata Maiti @Subhachem]

Happy to share our just published @NatureComms article from @IiserMohali @DCS_IISERMOHALI Thanks to @ANRFIndia for funding. Hard work done by @Rishiram7777 Niranjani @NandhaEttikkan #ReactionDiffusion based system
https://t.co/ye3v4cgpDS

[Jogender Singh @Jogender_Singh7]

I’m thrilled to share that our latest work, led by PhD scholar @_Das_Priyanka, is published in @embojournal!
Using a bacterial mutant library screen, we identified that bacterial-induced ROS extends C. elegans lifespan by disrupting its iron homeostasis. https://t.co/HXuREOt6Ei

[ShorterLab @ShorterLab]

Phase separation to buffer growth-mediated dilution in synthetic circuits: Cell https://t.co/k9dN1bGOwf

[Rachna Chaba @ChabaRachna]

Excited to share Deeptodeep’s PhD work https://t.co/QX3uNc6F5o Congrats on first & co-corr. authorship! We uncover redox switch as a novel mode of activation of E. coli envelope protease DegP that enables it to integrate various stress cues @caughtnd_act @DBS_IISERM @IiserMohali

[Samrat Mukhopadhyay @SamratLabMohali]

Yesterday, we had an amazing dinner with the members of my lab and @MilyBhLab at our apartment. It was fun (I was made to play guitar🎸and sing old songs😃). This was a homecoming for my former student @Harshita3110 & a send-off for @aroralisha20, who is leaving for her postdoc.

[Rout Lab @RoutLab_RU]

Nuclear Pore Complexes (NPCs) are the gateways to the nucleus, but how can they be both rapid and picky, even for very large cargoes? To answer this question, we built the most detailed data-driven model to date of transport through NPCs.
https://t.co/DWh3XMWZPL

[ShorterLab @ShorterLab]

Hijacking a bacterial ABC transporter for genetic code expansion: https://t.co/RFPxk4HAoA

[Jogender Singh @Jogender_Singh7]

Happy to share final version of our work in @eLife! We reveal how inhibiting the UFD-1-NPL-4 complex in C. elegans triggers an aberrant immune response, reducing pathogen load but ultimately compromising host survival. @aaballay1 @RajneeshRao16 @DBS_IISERM https://t.co/O2QwXWXzxZ

[Samrat Mukhopadhyay @SamratLabMohali]

Happy to share our community note published in Nature Communications. In this 14-page article (34 authors from 9 countries), we discuss current practices in biomolecular phase separation and hope it will be useful to the biomolecular condensate community.
https://t.co/UgwnvPpOk2