Jesse Rowley

Scientist at the University of Utah studying #platelets, megakaryocytes, and gene expression. All views expressed are my own.

[Jesse Rowley @rowleyresearch]

Our AJHG study introduces high-efficiency CRISPR HDR in CD34+-derived megakaryocytes to functionally classify platelet gene variants in their native context. We resolve several challenging Glanzmann Thrombasthenia VUSs in ITGA2B/ITGB3 #Platelets #CRISPR https://t.co/vTRSnYYvie

[Jesse Rowley @rowleyresearch]

Functional classification of platelet gene variants using CRISPR HDR in CD34+ cell-derived megakaryocytes: The American Journal of Human Genetics https://t.co/vTRSnYYvie

[Jesse Rowley @rowleyresearch]

The Rowley Lab (https://t.co/CyQQ0AGf55) is hiring post-docs! Are you interested in mitochondria, megakaryocytes, platelets, hematopoietic stem cells, or CRISPR/CAS9 functional screens? Message me or apply at https://t.co/aYhEyRIZbF .

[SpaceX @SpaceX]

Watch Falcon 9 launch Dragon to the @Space_Station https://t.co/TsXSKh4yYs

[Jesse Rowley @rowleyresearch]

@JoePlatelet Why not make it really official by moving to Utah?

[Craig Morrell @CraigMorrell5]

The In-Press Preview of @alison_livada work is online https://t.co/MEvLm3blFq A lot of work went into her paper, finished just in time to return to the MD portion of her studies.

[Scott Cameron 🏴󠁧󠁢󠁳󠁣󠁴󠁿🇺🇸🫀🩺📟🔬🧫🧬🥋 @2Scottish]

Blocking a relatively unknown #cytokine creates a fountain of youth. #ForeverYoung https://t.co/1r9O974yTi

[AV Washington @AVWashingtonLab]

BDUC (bleeding disorder of unknown cause ) patients show reduced platelet adhesion/ thrombus formation.➡️ To diagnose BDUC, platelet light transmission aggregometry should be performed as a minimum assessment. Platelet transfusions can be a potential treatment option.

[Jesse Rowley @rowleyresearch]

Want to learn about platelets, megakaryocytes, hematopoietic stem cells, RNA-seq, CRISPR, and high throughput functional screens? We're hiring a post-doc: https://t.co/NlwmZtfeee

[Andrew Johnson @ADJomics]

Our new article on factors influencing Platelet assays (e.g., blood draw time, time to test, age, sex, medications, technician, seasonality) and inter-assay correlation in >3,400 people is now online: https://t.co/dzDZLSQBJL @RPTHjournal @isth

[Jesse Rowley @rowleyresearch]

@robinsall @mbeisen Complete stories = science fiction.

[Abdullah Khan @AbAttacks]

Morning everyone! Pleased to share a detailed protocol of our bone marrow organoid approach in @NatureProtocols :

https://t.co/nh050lwgbx.

[Craig Morrell @CraigMorrell5]

Pre-print of our work led by Chen Li is online at Circ Res. Chen put a lot of data together to identify new ways platelets regulate monocyte immune responses. https://t.co/9Lw73GjhyM

[Dr. Jeffrey Berger @PlateletDoc]

Important step forward in #PrecisionMedicine - Platelet RNA Biomarker of Ticagrelor responsive genes Is associated w #platelet fxn and #cardiovascular events - Collaborative effort betwn @DukeCardiology and @NYUCVDPrevent @TessaJBarrett @nyulangone https://t.co/LUti2uXc9d

[Circulation Research @CircRes]

Jacob et al found that #MFN2 promotes #mitochondrial fusion in #megakaryocytes to maintain #platelet lifespan, & impacts function, ischemic #stroke, & #lung injury in mice at https://t.co/vQLRI1Pa6j

@rowleyresearch @racampbell04 @FrederikDenorme @IntmedAbel

[E. Dale Abel @IntMedAbel]

Here is the next one in @CircRes congrats to @rowleyresearch @jacob_shancy @racampbell04 @RhondaSouvenir @UU_MolecularMed showing #mitochondria dynamics via MFN2 regulating platelet activity. A good week for papers.
https://t.co/y1jTOqIyP3

[Jesse Rowley @rowleyresearch]

Who are the leaders in the field of inherited platelet disorders? This is what ChatGPT said. Paul Bray is retiring this month. He has been a stellar mentor and I have been fortunate to work with him. Shout out to the others too for their work recognized by AI :)

[Journal of Clinical Investigation @jclinicalinvest]

The PAR4 Thr120 variant influences platelet-neutrophil interactions and stroke outcomes: https://t.co/T0mu25h1m2
@racampbell04 @FrederikDenorme @MaryCushmanMD
#Hematology #Neuroscience