Pharmaceutical Sciences Ph.D. student at @UTHSC | Cancer Drug Discovery and chemotherapy | tubulin inhibitors for pancreatic cancer and prostate cancer.
There is no such thing as a perfect leader.
In fact, if someone claims to be a perfect leader, they are probably not even a good leader, as they lack the self-awareness needed to seek out feedback and continue to grow and improve.
Very interesting #OpenAccess preclinical study on MRTX1133 in @CR_AACR from @RoswellPark:
The extracellular niche and tumor microenvironment enhance KRAS inhibitor efficacy in #PancreaticCancer
https://t.co/O3Hw2IvmIy
The study uses a variety of patient derived & syngeneic models to identify how KRASinh alters cell autonomous signaling (including antigen presentation) as well as cell extrinsic tumor microenvironment changes in myeloid & T cell compartments.
As always don’t neglect to parse the supplemental data which contains a lot of profiling data, including potential immune checkpoints that are altered in setting of KRASi.
Welcome to a brief thread on tumor-associated macrophages and their regulation in pancreatic cancer brought to you courtesy of the hard working folks at @UMICHpancreas.
And my daily routine:
I wake up at 5 am.
Get to the gym at 5:30 am.
While working out, I listen to a science podcast for 1h.
Have breakfast and respond to emails at 7:30 am.
Reach to my lab at 8 am.
Work until 6 pm.
Have a dinner at 7 pm.
Read research reviews for 60 mins.
Read a book for another 60 mins.
Write down the work plan for the next day.
9 pm: I’m in bed, thrilled to start another super-day in 8 hours.
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Sounds perfect, right?
Except that this is not real. It’s NOT about me.
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In real life:
- I can get sick of office work
- I can get sick of writing grants, papers, reports
- I can get sick of working in a lab (hell, yes!)
- I can get too tired for a gym
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My life as a scientist is not about productivity.
It’s about creativity and fulfillment.
Such a daily routine can quickly exhaust us, mentally and physically.
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As a student, postdoc or faculty:
Do NOT feel guilty when you get sick of your lab duties.
Do NOT feel ashamed of your slow writing process.
Do NOT get upset by your mental and physical fatigue.
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Your strength is in your personality and curiosity. Not a productive daily routine.
#AcademicChatter #AcademicTwitter #Phd
The single cell tsunami of the human endocrine pancreas has not yet crested @NatureComms Turns out there are many distinct subtypes of endocrine cells and progenitors https://t.co/kWPZMYzMYa
This photo of 52 books is circulating on Twitter.
I have a PhD in literature with a focus on literary genres.
Here's my take as a literary scholar:
Read any one of these and you'll have read them all.
They're all the same.
In academic life, details are your friend but perfection can be your enemy. Yes, that proposal must have the correct font size, margins, and section headers. However, none of that matters if it never gets submitted because it’s never *quite* as good as it could be with more work.
Found an email I had saved from ~25 years ago, written by a beloved mentor and teacher, while combing through old documents.
“Success comes in many ways. For some it comes with the satisfaction that they have overtaken others, for others it comes hand in hand with others.”
Don't miss next week's 2023 FDA Science Forum! You'll get to see first-hand how FDA's researchers are using novel science and technologies to inform FDA’s regulatory decision-making — and drive innovation. Free registration here: https://t.co/5WBIFv9Ibi
Impressive collection of papers @CD_AACR! #KRAS is finally druggable, also beyond the G12C allele, and there is hope this work will benefit a large number of people with cancer
Just accepted for #publication! Be on the lookout for this #pancreaticcancer paper focusing on the different mouse and cell line models in vivo with the sole treatment of the CXCR1/2 inhibitor! Wish I could be @AACR this week to talk about it! #womeninscience@AcademicChatter
"The Best of the AACR Journals” is a collection of our most cited research articles published in 2020 and 2021 across the AACR journals. Check it out:
https://t.co/3GqcfuOFcA