Rumi Habib

Postdoctoral researcher at the University of Pennsylvania studying virology, immunology, and protein engineering | Emory '19 | Penn '25 | 🇵🇰

[Science Immunology @SciImmunology]

A new Science #Immunology study in macaques identifies the V2 apex region of the #HIV envelope as the most common target for broadly neutralizing antibodies (#bNAbs) and finds that B cell priming is the bottleneck to bNAb induction. @rumihabib
https://t.co/8sL8p9W5zT

[Science Immunology @SciImmunology]

Two new animal studies show that B cell priming is key to induce broadly neutralizing antibodies (#bNAbs) against #HIV and demonstrate that a single immunization that targets bNAb precursors can induce potent neutralization.
📃: https://t.co/8sL8p9W5zT
📃: https://t.co/M3lfYUbYC7

[Amelia Escolano @EscolanoLab]

Enjoying a great #HIVR4P2024 meeting by @iasociety with @NachoRelano and @rumihabib from @TheWistar in Lima this week😍. Thank you to the @gatesfoundation for hosting a fun reception this evening. #HIVvaccines 💪

[bioRxiv @biorxivpreprint]

HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene https://t.co/eL5hDF7xJO #bioRxiv

[Masopust Vezys Lab @Masopust_Vezys]

Authored by Andrew G. Soerens et al, we show that #Tcells are capable of proliferating in response to iterative stimulation for over 10yrs! And produce enough progeny to occupy a volume 30,000x the Earth's volume! @Nature https://t.co/jPfmX2Ilrq

[Hensley Lab @SCOTTeHENSLEY]

We developed a new multivalent mRNA vaccine against all known influenza virus subtypes. Our study describing the vaccine was just published in @ScienceMagazine. 1/n
https://t.co/HxTKm47EC3

[Amelia Escolano @EscolanoLab]

Great and productive #CAVDannualMeeting by @gatesfoundation in Seattle last week. We presented our work generating #NewMouseModels for #HIV #Vaccine development by Belen Palacio @mb_palacio, Ignacio R. Relaño @NachoRelano and Ashwin Skelly at @TheWistar

[bioRxiv Immunology @biorxiv_immuno]

A germline-targeting chimpanzee SIV envelope glycoprotein elicits a new class of V2-apex directed cross-neutralizing antibodies https://t.co/UBadd7H3wY #biorxiv_immuno

[nature @Nature]

Why are Pakistan’s floods so extreme this year? https://t.co/IZO729zJcf

[Nature Rev Immunol @NatRevImmunol]

Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies https://t.co/Xq5NJdPk1r

[bioRxiv @biorxivpreprint]

Virus-like transposons cross the species barrier and drive the evolution of genetic incompatibilities https://t.co/X2QO5cnvSZ #bioRxiv

[Vincent Graziano @VinnieViruses]

Incredible paper out in @Nature https://t.co/V2jQYykOY1

[Kulp Lab @KulpLab]

Our latest HIV vaccine paper is out! We demonstrate that an Env-encoded nucleic acid vaccine retains a native-like trimer antigenic profile in vivo and results in unique neutralization which we mapped by cryo-EM.

https://t.co/XYMVSmWl2V

[Kulp Lab @KulpLab]

Our SARS-CoV-2 nanovaccine paper is out! We describe the development of immune-focused receptor-binding domain nanoparticle vaccines which elicit potent and durable neutralizing antibodies against SARS-CoV-2 and variants of concern. @CellReports
https://t.co/e5lTUfMR6Y

[Patrick Kearns @kearnsneuro]

Phenomenal paper just published in Science persuasively demonstrating that EBV causes most if not all multiple sclerosis.

Phenomenal epidemiological design and technical achievement. 👏

https://t.co/LcNFvKHiUp

[Rumi Habib @rumihabib]

"In Pakistan, more than 40 million children were unable to receive measles vaccination and around 50 million children missed polio vaccination in 2020. Moreover, more than 36 million children did not receive vitamin A supplementation in 2020."

[Nature Rev Immunol @NatRevImmunol]

Negative impact of the COVID-19 pandemic on routine childhood immunization: experience from Pakistan https://t.co/4t99O5eoEi

[John Burn-Murdoch @jburnmurdoch]

One of the most startling Covid charts I’ve made in a long time, on vaccine inequality:

Rich countries have given out more booster shots in the last 3 months, than poor countries have given out total doses all year.

@donatopmancini’s story: https://t.co/rW7nsCQk4a

[Cell Host & Microbe @cellhostmicrobe]

Virus vaccines: proteins prefer prolines. Sanders & Moore review a method devised for #HIV #vaccine development that was utilized in most #COVID19 vaccines-- stabilization of the spike protein by appropriately positioned proline amino acid substitutions https://t.co/WaghGhhnVC