PhD opportunities @BristolBiochem@SWBio_DTP including a curiosity @LabCollinson : a new look at a biochemistry classic -seeking an explanation for von Heijne’s ‘positive-inside rule’
Collaboration with Paul Curnow, Will Allen, @RobinCorey1 & @RobinHoodBS2
https://t.co/cyxpDO1TU7
Our newest work on Snx14 is online at @PNASNews! Here, we dissect mechanisms underlying neurological disease SCAR20.
We find Snx14 is an important ER protein required for ER-LD crosstalk & to help maintain the cellular lipid saturation profile.
https://t.co/dPbqIjkHtU
Pleased to share our team’s most recent study, out now in @PNASNews! Through direct interactions with lipid droplets, lysosomes are constantly nibbling away at the fat within our liver cells!
https://t.co/ZlD2xN418i #NAFLD#MAFLD
@manojbio@PNASNews Hi Manoj, this is a great question and one we are trying to work out. Which proteins mediate these interactions? Can we stabilize these interactions? Are there certain disease contexts where these interactions are perturbed? Lots of work to do!