I find it difficult to move on, not just from people but from phases of life, rooms I’ve lived in, foods I’ve obsessed over, series I’ve binged, anything that has made me happy over a period of time.
All of you wonderful fathers who bring your beautiful babies to clinic and are so engaged in their care and understand their needs are amazing! You exemplify what fatherhood should be.
There are still people who get excited to show you a cool rock they found, a strangely shaped cloud, a tiny frog, a pretty leaf, or a sky full of stars. That’s the kind of energy I want around me for the rest of my life.
there is something incredibly satisfying about reading the first page of a book, and immediately something in your brain sits up and goes 'oh, i'm going to like this' — and then every subsequent page proves you right.
On mentorship, a good strategy is to think about how you can help your mentor.
That way, you're more likely to be entrusted with more tasks and opportunities.
Concept #NEETPG
Pitting vs non-pitting edema
Students memorise a list of causes for each and never ask the obvious question - why does pressing one leave a dent and the other doesn't?
It comes down to one thing: what is the fluid mixed with? Is it free water, or is it water bound to something?
In pitting edema, the fluid in the tissue is mostly free, mobile water - a watery, low protein transudate. Push your thumb in and that loose water just squishes off to the sides. It needs a few seconds to seep back, and till then you're looking at a dent. So the pit is nothing fancy - it's just water that got pushed away and hasn't come back yet. This is because of heart failure, low albumin states(nephrotic/cirrhosis), venous obstruction - anywhere hydrostatic pressure pushes plain water into the tissue.
In non-pitting edema, the fluid isn't free - it's trapped. Either it's a protein-rich fluid that's too thick and sticky to be pushed aside, or the tissue itself has been filled with solid material that water binds to. Press your thumb in and there's nothing loose to displace, so no dent forms. The tissue feels firm, even doughy.
So the whole rule is about mobility. Free water moves when you press ➡️ pit. Bound or thickened fluid can't move ➡️ no pit.
Now the two classic non-pitting situations, and why each fails to pit:
1. Lymphedema: it is a blockage problem. Lymphatics are jammed like Gurugram traffic, so protein heavy fluid keeps backing up. And protein doesn't just sit there quietly - over months it drags in fibrosis and the tissue goes thick and firm. So now there's no loose fluid to shove around, the skin's just dense. Nothing to displace, no pit. Filariasis is the one they'll show you in exam.
2. Classic Myxedema: it is the odd one out, because here it's barely even "fluid" !! When thyroid is low, these molecules called glycosaminoglycans - hyaluronic acid, chondroitin - start piling up in the skin. And they're water-magnets (literally like kids diapers). They grab water and trap it in a kind of gel. So the water isn't free anymore, it's locked up. Press it and nothing moves, because there's nothing loose in there to move. No pit. No dent.