sevahn vorperian

postdoc @genentech. RNA, biotech, and honey badger enthusiast. she/her.

[sevahn vorperian @sevahnv]

Modern medicine as we know it relies on antimicrobial drugs and the marketplace sustaining their development needs help. The PASTEUR Act is critical in addressing #AMR while we still have time. Pleased to share the opinion piece I wrote with my doctoral advisor @StephenQuake

[STAT @statnews]

Opinion: Look no further than the coronavirus pandemic to see an immediate and high-profile example of the evolutionary battle between microbes and humans and the antimicrobial resistance it breeds. https://t.co/tq0oJHWnG8

[Kevin K. Yang 楊凱筌 @KevinKaichuang]

We made FLIP2, a protein fitness benchmark spanning seven new datasets, including enzymes, protein-protein interactions, and light-sensitive proteins, as well as splits that measure generalization relevant to real-world protein engineering campaigns.

[Nature Biotechnology @NatureBiotech]

Cell type inference in cell-free nucleic acid liquid biopsy - @sevahnv @genentech https://t.co/6ub1fRbfT8

[sevahn vorperian @sevahnv]

Are you building a liquid biopsy or developing a biomarker panel? Check out our new review on cell-type inference in #cfDNA and #cfRNA liquid biopsy — now out @NatureBiotech!
https://t.co/62GNKAIMt4

@StanfordEng @genentech @ChanZuckerberg @FoundationATCG @czbiohub

[Kevin K. Yang 楊凱筌 @KevinKaichuang]

You have until Dec 1 to apply to the bioml PhD research internship!

This is where you apply to work with me, @alexijielu @avapamini @lorin_crawford or Kristen Severson!

(new) link and some instructions below

[sevahn vorperian @sevahnv]

As a proof-of-concept for urine RNA liquid biopsy, we show that mRNA in human urine reflects cell type-specific signal from hard-to-biopsy tissues with low abundance in blood-based cfRNA liquid biopsy & integrate with the urine metabolome @Clin_Chem_ADLM https://t.co/JA7RrVKnyA

[sevahn vorperian @sevahnv]

+1

[Itai Yanai @ItaiYanai]

I don’t like the term “trainee” because it suggests that at some point the training ends, when really what I love about science is that you keep improving in the art of making discoveries.

[Jack Chun-Ting Liu @ctliu629]

Excited to share my paper @NatureComms on the Taxol biosynthesis @Sattely_lab with some help from the @Keasling_Lab 🥳 🎉
Really happy to have contributed to the studies of this amazing molecule 😊
https://t.co/mpw3frSwVJ (1/2)

[sevahn vorperian @sevahnv]

@BrianCDeFelice @jabuonomo @liaojoe1 @CarolynBertozzi @StephenQuake #liquidbiopsy #earlydetection #cfRNA

[sevahn vorperian @sevahnv]

Delighted to share our work integrating RNA and metabolomics to resolve cell type repertoires in human urine. We observe a distinct cell type composition from blood plasma originating from hard-to-biopsy tissues, offering promise for a new generation of liquid biopsies.

[bioRxiv @biorxivpreprint]

Multiomics characterization of cell type repertoires for urine liquid biopsies https://t.co/o0P3HGqvpK #bioRxiv

[sevahn vorperian @sevahnv]

@RHAbbady congrats!!!!

[sevahn vorperian @sevahnv]

hey biotech newcos - check out this resource on preparing federal #grants for small businesses! it was terrific working with Dr. James Coates @decisivepointvc @stanfordbiotech

[StanfordBiotechGroup @stanfordbiotech]

Want to maximise the impact of the technology your startup is building? Check out this awesome resource for Federal Grant funding for Startups by James Coates @decisivepointvc and SBG's own @skayaneh
https://t.co/xPwaRfsatY
#StanfordBiotechInsights

[sevahn vorperian @sevahnv]

🙅🏻‍♀️

[Tara Basu Trivedi @tbt94]

He’s a 10 but he’s starting an AI-for-drug-discovery startup with no biology background

[sevahn vorperian @sevahnv]

easily the hepatocytes, though the Clara cells come in for a close second :)

[Fabian Theis @fabian_theis]

What’s your favorite cell type?

[sevahn vorperian @sevahnv]

@Abhi_Immuneng @NSF @Green_Polymers @KaushalRege_Lab @keselowsky @think_little @Inamdar_Sahil @Joslyn52267476 @ASUChemEng Congrats Abhi!!!!!!

[Nature Biotechnology @NatureBiotech]

Cell types affected by various diseases are inferred from cell-free RNA https://t.co/hjqYQT8Oqz

[Stephen Quake @StephenQuake]

Cell type deconvolution of cell free RNA and potential clinical applications in recent work by @mira_moufarrej, @skayaneh, and me.

@NatureBiotech https://t.co/jzhfxahQGv

[Cornell CVG @CornellCVG]

Check out this paper from @skayaneh, @StephenQuake, and the Tabula Sapiens Consortium at @cziscience where they used single-cell and cell-free RNAseq data to track cell-type-specific pathologies in a variety of diseases! https://t.co/aIqEJ8Ak86

[sevahn vorperian @sevahnv]

"We’re optimistic that this is only the beginning – both for the unprecedented cellular resolution that we can achieve in noninvasive liquid biopsy as well as the for the clinical insights we can derive using single cell data and whole organism transcriptomic cell atlases."

[Nature Biotechnology @NatureBiotech]

Co-authors @skayaneh & @StephenQuake go #behindthepaper on working at the nexus of single cell transcriptomics and liquid biopsy https://t.co/wCqz3npLbY

[sevahn vorperian @sevahnv]

Cell free RNA liquid biopsy is decomposable into its cell types of origin in health and disease. Excited to share my work with @mira_moufarrej, the #TabulaSapiens consortium, and @StephenQuake now published in @naturebiotech

[Nature Biotechnology @NatureBiotech]

Cell types of origin of the cell-free transcriptome https://t.co/hjqYQT8Oqz

[Prof. Dame Sally Davies @DameSallyDavies]

The 'silent pandemic' is not silent anymore.

New data, published in today’s #Lancet, show the true global cost of #AMR.

We must use these data as a warning signal to spur on action at every level.

#AMRSOS 👉 https://t.co/PsGjirim7N