Shayan Mashatian

AI Innovation | Serial Entrepreneur | Podcast Host | | | | | |

[Shayan Mashatian @shayanrm]

@garrytan Interesting, I am surprised you have not been one of the early Uber investors.

[Shayan Mashatian @shayanrm]

https://t.co/8WA44e7g7P

[Shayan Mashatian @shayanrm]

Because.

[Shayan Mashatian @shayanrm]

https://t.co/wfcqQWC1Wa

[Shayan Mashatian @shayanrm]

It's amazing what has happened in clinical medicine in the last five weeks!

- 55% progression-free at 7 years in metastatic lung cancer.
- A 60% reduction in death risk in metastatic pancreatic cancer.
- 62% lower LDL cholesterol from a single infusion — possibly for life.

These aren't projections. They are trial readouts from the last five weeks.

[Shayan Mashatian @shayanrm]

@eastdakota @NoamTenne @Cloudflare Why someone should hate your service? No one forces them to use it! Don’t use it if you don’t like it, simple!

[Shayan Mashatian @shayanrm]

@DavidSacks @pmarca Many companies don’t hire for some roles they would normally do because AI tools can cover some of the work at a lower cost, faster, and of higher quality. Maybe a shift is happening; however, changes in hiring patterns are indisputable.

[Shayan Mashatian @shayanrm]

@sophie_launch https://t.co/Wg8Ah5IXXu

[Shayan Mashatian @shayanrm]

@AdamSinger @mbeckett Someone recently proudly told me I made an app with Loveable, well, it’s equal you say I know how to use PowerPoint for a meeting. Almost same value.

[Shayan Mashatian @shayanrm]

@samanthajeanneb https://t.co/SPIKgIkiJ5

[Shayan Mashatian @shayanrm]

https://t.co/auGqL5BZrO

[Shayan Mashatian @shayanrm]

Introducing Plot, the ultimate AI storyteller!

Drop the screenshots you already have. Plot scripts the narration, paces the cut, and renders a polished MP4 explainer with AI voiceover — ready for App Store previews, launches, and pitch decks. Need something lighter? Ship a quick GIF for free. No video editor, no screen recorder.

[Shayan Mashatian @shayanrm]

@gregisenberg o3 was the equal moment to iOS 12. After that, everything been incremental improvement.

[Shayan Mashatian @shayanrm]

@adocomplete What’s its cost?

[Shayan Mashatian @shayanrm]

Hey @NotebookLM, did you notice we used you for personalized patient education and engagement and published a paper about it?! https://t.co/I7VY5hySW8

[Shayan Mashatian @shayanrm]

@elonmusk @PeterDiamandis Any plans to release a small, open source reasoning model?

[Shayan Mashatian @shayanrm]

@paulg Oh yeah, I just go with the first option they provide, wouldn’t spend time to select the wrong answer!

[Shayan Mashatian @shayanrm]

@dhh What’s your default reasoning effort? Do you keep it at medium?

I also found it very weak in UI adjustments. I was wondering what’s your experience.

[Shayan Mashatian @shayanrm]

@vahididoo I have also heard Pay it forward

[Shayan Mashatian @shayanrm]

@nikitabier @levelsio @X That was one of the most stupid rules you had to deal with. I applied once and received a response that basically said we didn’t find anything notable about you. There was no way to get a verification that you are a real person, not a bot.