Shehzad Huda MD

Neonatologist @Pediatrix Medical Group, Houston| Associate Professor, U of Houston COM. #neonatology #NecrotizingEnteroColitis #Nutrition #ClinicalResearch

[Neonatology Journal Club @NeonatologyJC]

#142

“Prophylactic CPAP at Cesarean Birth in Late-Preterm Newborns”

A multicenter pilot RCT addresses a crucial question: whether prophylactic CPAP at the time of C-section reduces the risk of respiratory complications in late-preterm newborns. This is particularly relevant because late-preterm infants born by C-section are already known to be at a higher risk of respiratory issues.
#JournalClub #NeoTwitter

@AAPneonatal @AmerAcadPeds @Okla_Childrens @TheAlexBrighton @RileyChildrens

https://t.co/6ir71OR2Pf

[Neonatology Journal Club @NeonatologyJC]

#141

“Less-Invasive Surfactant Administration in the Delivery Room: A Pilot Randomized Clinical Trial”

A pilot randomized clinical trial comparing the DR LISA method to the NICU early-rescue LISA method in infants born between 22- 25 wks of gestation. This trial is the first of its kind to test the administration of surfactant via a thin catheter immediately at birth in this specific population.

#NeoTwitter #Neonatology #JournalClub
@AAPneonatal @AmerAcadPeds @vkakkilaya @TinyBabyCollab @The_BPD_Collab
@UTSWMedCenter

https://t.co/2uYTFyNQK8

[Shehzad Huda MD @shehzadhudamd]

Excellent work by @vkakkilaya and team. A pioneering pilot RCT evaluating delivery room LISA in infants born at 22 to 25 weeks. Looking forward to the next phase. #NeoTwitter #Neonatology

[Neonatology Journal Club @NeonatologyJC]

#141

“Less-Invasive Surfactant Administration in the Delivery Room: A Pilot Randomized Clinical Trial”

A pilot randomized clinical trial comparing the DR LISA method to the NICU early-rescue LISA method in infants born between 22- 25 wks of gestation. This trial is the first of its kind to test the administration of surfactant via a thin catheter immediately at birth in this specific population.

#NeoTwitter #Neonatology #JournalClub
@AAPneonatal @AmerAcadPeds @vkakkilaya @TinyBabyCollab @The_BPD_Collab
@UTSWMedCenter

https://t.co/2uYTFyNQK8

[Neonatology Journal Club @NeonatologyJC]

#140

“Surfactant replacement therapy in preterm infants with congenital heart disease: Physiological concepts and therapeutic considerations,” published on April 20, 2026.

This open-access article offers a comprehensive perspective on a question that many of us have pondered at 2 am but never had the opportunity to explore in detail. It delves into the physiological concepts and therapeutic considerations surrounding surfactant replacement therapy for preterm infants with congenital heart disease. #PedsCards

@JPerinatology @NatureMedicine @SpringerNature @AAPneonatal @AmerAcadPeds @uiowa @NeoHemodynamics @CCardiology

https://t.co/kdFSk0xN5g

[Neonatology Journal Club @NeonatologyJC]

#139

“We’re going bananas”

Single-center retrospective study, 43 infants in a level IV NICU, testing banana puree as a feed thickener for dysphagia. Fun title, serious clinical question.
#JournalClub #NICU
@JPerinatology @AAPneonatal @AmerAcadPeds
@RainbowBabiesN @cwru @UniversityofNo7
@NASPGHAN @ESPGHANSociety

https://t.co/sYaZxQQyM1

[Neonatology Journal Club @NeonatologyJC]

Infants who got oral vitamin K instead of IM still had higher bleeding odds than the IM group, aOR 2.26 for any bleeding. So oral isn’t a clean substitute here, adherence to the multi-dose schedule is doing a lot of work. #ClinicalPearls

[Neonatology Journal Club @NeonatologyJC]

#138

A huge Swedish registry study on newborn vitamin K prophylaxis and infant bleeding,

In @JAMAPediatrics, Published Online: July 13, 2026.

Simatou et al, Karolinska Institutet. Grab your coffee, this one has 2 million babies in it.

#JournalClub #PedsID

https://t.co/i3zawtTHiq

[Neonatology Journal Club @NeonatologyJC]

#137
“Previable Preterm Premature Rupture of the Membranes Reaching Viability: Canadian Outcomes”
By Gojic, Wang et al, JOGC 2026.

Big multicentre Canadian Neonatal Network data on PPROM <22 weeks. Worth a close read for anyone in MFM or neonatology.

#JournalClub #MedTwitter #PPROM

@ElsevierConnect @ClinicalKey @CanPaedSociety @CNFUN_RCSN @EBNEO

https://t.co/1FACOMVkqP

[Neonatology Journal Club @NeonatologyJC]

#136
“Limbic System Microstructure in Neonates With Antenatal Opioid Exposure,” Published July 2, 2026 in @JAMA_current.

Case-control DTI study out of the OBOE study, 4 US sites. Bigger and better controlled than most of what’s come before in this space.
#PedsNeuro #Neonatology

@DevBrainLab
@CincyKidsNeo @UofCincy
@RTI_Intl @ChildrensPhila
@CHOP_Research @PennMedicine @UABNews
@cwru @EmoryUniversity
@TuftsUniversity

https://t.co/nUWj0JiMbA

[Neonatology Journal Club @NeonatologyJC]

#135

From the @JPerinatology explores a question often overlooked in NICU research: what do bereaved parents actually experience when we ask them to participate in research about losing their child?

The study, titled “Comfort, Benefit, and Distress: An Exploratory Study of Research Experiences of Bereaved Parents in the Neonatal Intensive Care Unit,” aims to shed light on the emotional and psychological impact of participating in research in this vulnerable population.

Published on June 22, 2026.

#JournalClub #NeonatalICU #PalliativeCare

@AAPneonatal @AmerAcadPeds @EBNEO @BostonChildrens

[Neonatology Journal Club @NeonatologyJC]

#134

Today, we’re exploring a paper that will likely give every neonatologist something to think about:

“Variation in Stabilization and Resuscitation Practices at Birth of Preterm Infants Among 12 National or Regional Neonatal Networks,”

published in @ActaPaediatrica by Helenius and colleagues.
#Neonatology #JournalClub

@AAPneonatal @TinyBabyCollab @uabpeds @EBNEO @StanfordNeo @UTHealthNeo @HopkinsNeo @eNeoResearch

https://t.co/kIOa5rHxOv

[Neonatology Journal Club @NeonatologyJC]

#133

New research published in @JAMAPediatrics, online June 15, 2026, presents a comprehensive dataset spanning 70 years of spina bifida survival data from Utah’s population database, covering the period from 1950 to 2020. This long-awaited dataset is particularly valuable as most prior research ends well before 2010. It is highly recommended for a thorough examination.

“Survival Trends of People With Spina Bifida From 1950-2020”

#JournalClub #SpinaBifida #PedsUro
@JAMA_current @NCHUrology @JHHPedsUro @PedsUroOnc @PedsUroOnc @PUNSUrology @Peds_Urology @ManagingCase @PedUrologyBook

https://t.co/fii8Tlg98u

[Neonatology Journal Club @NeonatologyJC]

#132

@veeraltolia et al., explore the relationship between probiotics and necrotizing enterocolitis in preterm infants following the 2023 FDA warning. This clinically significant question is currently at the forefront of every neonatologist’s mind.

“Probiotics and necrotizing enterocolitis in preterm infants following the food and drug administration warning actions”

#Neonatology #NEC #Probiotics

@NatureMedicine @Nature @JPerinatology @AAPneonatal @AmerAcadPeds @NECsociety @EBNEO @nicupodcast @Pediatrix @NeoToday @StanfordNeo @BCMNeonatal @AmyHairMD @kaashif_ahmad @ravimpatelmd

https://t.co/zngSnOZFfm

[Neonatology Journal Club @NeonatologyJC]

#130

A recent study published by Gränse et al. investigates the potential of topical dexamethasone eye drops in preventing the progression of type 2 Retinopathy of Prematurity to the stage necessitating laser or anti-VEGF treatment. This study addresses a pertinent clinical question with significant implications.

“Treating Retinopathy of Prematurity with Dexamethasone Eye Drops: A Difference-in-Differences Study in Sweden Using Register Data”
#ROP #NeonatalOphthalmology #JournalClub

@EBNEO @AAPneonatal @nicupodcast

https://t.co/f33w8aCImn

[Neonatology Journal Club @NeonatologyJC]

#129

Fraiman et al. conducted a comprehensive study to examine racial and ethnic disparities throughout the entire Early Intervention care process for very preterm infants in Massachusetts. The study covered every single step of the care cascade.

“Inequities Along the Early Intervention Care Cascade for Very Preterm Infants.”

#JournalClub #NeoTwitter #HealthEquity
@JAMA_current @JAMAPediatrics

https://t.co/ZDHgP73IqB

[Neonatology Journal Club @NeonatologyJC]

#126

Just read the SMART-PDA pilot RCT by @souvik_neo (Mitra et al) in @ADC_BMJ Neonatal.

First trial to exclusively enroll infants under 26 weeks GA for selective early PDA treatment.

#NeonatalMedicine #PDA #JournalClub

https://t.co/OPWhlpBG5Q

[Neonatology Journal Club @NeonatologyJC]

#125

We spend years debating surfactant timing, caffeine doses, and ventilator modes in the NICU, yet the PEEP we set in the first 20 minutes of life has largely been guided by habit. Tingay et al. finally put this to a proper test. The POLAR Trial asks a deceptively simple question: how much PEEP should we actually be giving extremely preterm infants in the delivery room?
#NeonatalMedicine #POLAR #JournalClub

@Ped_Research @NatureMedicine @SpringerNature @The_BPD_Collab
@TinyBabyCollab

https://t.co/RlMeQt9Sx5

[Neonatology Journal Club @NeonatologyJC]

#124

SILDI-SAFE RCT - Safety of Sildenafil in Premature Infants with Severe BPD.
Jackson et al., May 7 2026.

A long-awaited safety trial for a drug used off-label daily in NICUs.

#Neonatology #BPD #JournalClub

@ElsevierConnect @JPediatr
@The_BPD_Collab

https://t.co/FX7okq4CsZ

[Neonatology Journal Club @NeonatologyJC]

KEY CONCEPT - SELF-FULFILLING PROPHECIES:

Centers that intervene more aggressively at 22-23 weeks generate better outcome data; those that do not, generate worse data. These data are then incorporated into SDM discussions, reinforcing local norms. The “facts” presented to families thus reflect institutional philosophy, not pure biology. #NeonatalICU

[Neonatology Journal Club @NeonatologyJC]

#123

“When Facts Are Not Fixed: Rethinking Shared Decision Making at the Margins of Neonatal Viability”

A conceptual/philosophical analysis that challenges one of neonatology’s most entrenched practices.

#NeonatalEthics #JournalClub #Periviability

@SpringerNature @BioMedCentral @BMCMedicine @TinyBabyCollab

https://t.co/5ichHL7WzX