🔬Our preprint is out! "Genomic plasticity is a blueprint of diversity in Salmonella lineages". 🧬👩🔬 Thrilled to contribute to advancing our understanding of Salmonella pathogenesis. A huge thanks to my supervisors, @NobregaFL#Research#Salmonella 🌐 https://t.co/5J5pRRH6Dd
1/ A protein is a nanomachine - moving parts, does real work, changes shape to do its job. A gene editor is one of them: a molecular machine that hunts down a stretch of DNA and cuts it. We still borrow these machines from nature and tune them, because we don't understand them well enough to build our own. We started Mandrake to change that.
We just launched our first open ML challenge at @BioMandrake
The Retroviral Wall - predict which reverse transcriptase enzymes work for prime editing, without memorizing their evolutionary family.
$1K prize + co-authorship + real wet lab validation.
Effective management of #Salmonella infections requires understanding its dynamic evolution. @simrankushwaha@NobregaFL &co reveal how specific genomic regions influence the distribution of #pathogenicity factors in Salmonella #PLOSBiology https://t.co/KoO9DSHcTR
Happy to share the final version of our work at @PLOSBiology👇
https://t.co/Tlrov2Rmo9
Thank you to all the reviewers, and a big shoutout to first author @simrankushwaha 👏
1/9 In our latest preprint, led by @simrankushwaha, we looked at the complex world of Salmonella pathogenic diversity. 🦠 We analysed 12,244 Salmonella genomes for virulence, stress resistance, antibiotic resistance, and anti-phage defence. 🧵👇 https://t.co/W2KR24CcS8
Tune in for our first episode, where we had the pleasure to speak with Joana Azeredo (@azeredo_joana) about her lifetime research on bacterial biofilms! 🎙️🎉
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Please register yourself for EMBO | India Research Partnership event happening in 9 cities. Please register yourself ASAP, it's FREE (first come, first get). At @ccmb_csir, I am coordinating the event. The details are here https://t.co/1g5afpNGst
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