Sean Langan, PhD

Human performance, physiology, sports, health, etc.
@splsystems on instagram
Check out my Substack ⬇️

[Sean Langan, PhD @spl5_]

@tiga_style Thanks man! Tryna work up to your level 🫡

[Sean Langan, PhD @spl5_]

Some generous downhills in there but fun race. Goal is to get in the 4:20s on the track by end of summer.

[Sean Langan, PhD @spl5_]

Only 120 pages in, but really fascinating book so far. Hard to believe how much regularity/predictability there is across diverse systems from plants to companies that all follow similar scaling principles.

[Sean Langan, PhD @spl5_]

@Brady_H I’m good for about 1 a year. And it never is any fun.

[Sean Langan, PhD @spl5_]

@Brady_H Probably equivalent to a 4:40-4:45 on the track lol but a good starting point. Trying to delay the inevitable speed decline as long as possible. Only thing that sucks is it’s hard to find competitive 1 mile races for people of intermediate ability 😂

[Sean Langan, PhD @spl5_]

@Calv2024 Unnecessary

[Jeroen Swart @JeroenSwart]

I love it when people overcomplicate physiology. It makes my job easier. I agree…what a mess.

[Louise Burke @LouiseMaryBurke]

These aren’t the highest rates of fat oxidation ever measured in a human - elite racewalkers who adapted to a keto diet for 6 days or 3.5 weeks showed higher rates - some at 2 g/min. But they raced at a slower speed when asked to perform in a real life race. You can’t outrun the stoichiometry of fuel production. Carbs produce more ATP per litre of oxygen than fat.

[Sean Langan, PhD @spl5_]

One perk of my current job is usually having a COSMED K5 on hand. With a bike and rower at home I’m collecting a ton of data on myself to determine biological variability of VO2 and technical error of our devices. Excited to build this out more over the next few weeks.

[gaut @0xgaut]

“how do I become a better runner?”

[Sean Langan, PhD @spl5_]

Love this race! Big improvement from last year with still some room to improve. Not that I'm running to win anything, but it's crazy that running nearly 3 min faster than last year only bumped me up 10 places. Now shifting focus to the mile/5k for the spring and summer.

[Sean Langan, PhD @spl5_]

I have historically worn cheap running shoes until the last year or so. Since I haven't been through the gamut of all the high profile kicks, take this with a grain of salt, but the Adidas evo SL has to arguably be the best shoe on the market. Especially the newer woven version.

[Sean Langan, PhD @spl5_]

@themovementDrZ 😂

[Sean Langan, PhD @spl5_]

Intervals are always going to be hard, but by adding some variability in the power output within each interval, you may to be able to get more bang for your buck. Read more at the link below.
https://t.co/DPUjHcMqia

[Sean Langan, PhD @spl5_]

Cool study on mitochondrial calcium and aging in skeletal muscle. I suspect research on novel polyphenol compounds is only going to keep growing in the next few years. https://t.co/cts5vheLSd

[Sean Langan, PhD @spl5_]

What makes VO2max relevant to health?
https://t.co/sQiA6urrZE

[Sean Langan, PhD @spl5_]

Favorite road race. 2nd mile is always a kick in the teeth. Think I’m still capitalizing on the newbie gains. 2min faster than 2023. Next goalpost <26min.

[Lars Nybo @Nyborger_Nybo]

well - try to ingest 120 grams of CHO (with ½ glucose and ½ fructose) and see what happens (just resting)

[David Bishop (🦋 also bluespotscience.bsky.social) @BlueSpotScience]

Our latest work: "Sprint interval exercise disrupts mitochondrial ultrastructure, driving a unique mitochondrial stress response and remodelling in men" has been accepted in Nature Communications and will soon be online 😊