Localised prostate cancer just changed. Again.
ESMO 2026 brings clarity on who to observe, who to escalate, and which trials actually matter 👇
🧠 Diagnosis
MRI before biopsy is standard
High-resolution US is a valid alternative (RCT n=678)
🧭 Low risk
Active surveillance is safe
ProtecT 15-yr data shows similar survival vs RP/RT
☢️ Radiotherapy
Shorter is better
CHHiP ➜ moderate hypofractionation
HYPO-RT-PC ➜ ultra-hypofractionation
PACE-B ➜ SBRT works in selected IR disease
📈 High risk
RT + long-term ADT saves lives
SPCG-7 | NCIC/MRC
Dose escalation improves OS (GETUG-AFU 18)
🚨 Very high-risk / cN1
RT + ADT + abiraterone is the new benchmark
STAMPEDE delivers MFS + OS benefit
🔁 Biochemical recurrence
Avoid routine adjuvant RT
Early salvage RT preferred
RADICALS-RT | RAVES | GETUG-AFU 17
High-risk BCR? Intensify
EMBARK supports enzalutamide + ADT
🧠 Bottom line
Risk-adapted care > overtreatment
Imaging-driven decisions
Escalate only when trials prove benefit
📖 Full paper in comment ⬇️
#OncoTwitter #MedTwitter #ProstateCancer #GUOncology
@OncoAlert@myesmo@esmo_open@asco@OncBrothers
@drozanbozkurt@UrolojikCerrahi It was a real pleasure and honor for us to host this wonderful meeting 🙏
Your valuable efforts and dedication were truly incredible—thank you so much; and we also sincerely thank all participants for their kind support 👏✨@UrolojikCerrahi@drozanbozkurt@spongios
RATSUS @UrolojikCerrahi (Reconstruction and Trauma Working Group of Society of Urological Surgery) successfully completed the 6th urethroplasty live surgery course with 80 in-person and 245 online participants. Thanks to all faculty and participants.
For short (<3 cm) bulbar strictures recurring after ≥2 endoscopic treatments, consider drug-coated balloon dilatation (paclitaxel):
📊 ROBUST-3: 6-mo patency 75% vs 27%, 1-yr retreatment-free 83% vs 22%
🔒 For those unfit for urethroplasty
#Strictures#EAUGuidelines
⚡️ NMIBC follow-up: what does the EAU recommend?
- Tailored schedule by risk level
- CT urography for high-risk patients
- No approved biomarker can replace cystoscopy
- BLFC & NBI help detect missed lesions
#BladderCancer@Uroweb
https://t.co/cAfik7Xphm
🛠️ Urethral reconstruction tips:
✅ Use a graft over a flap when both are equally suitable
❌ Don’t use tubularised grafts in single-stage repairs
🚫 Avoid hair-bearing flaps (scrotal/perineal) unless necessary
#UrethralStrictures#EAUGuidelines
https://t.co/zUduQjmwsG
Bu kez çok farklı bir yanımdan güzel bir haber vereceğim. İstanbul’un geçmişine merakımı bilenler biliyor. Blog, mikroblog filan derken iş meraktan biraz öteye gitti.
İlk kitabım Cam Kenarından İstanbul’un çıktığını, haftaya tüm kitapçılarda olacağını duyurmak heyecan verici…
🧾 New Cheat Sheet on Prostate Cancer Treatment by Stage
🔹 Low-risk: Active surveillance; avoid ADT
🔹 Intermediate-risk: Surgery or RT; ADT case-based
🔹 High-risk: Surgery/RT + long-term ADT
#EAUguidelines#ProstateCancer
Download Cheat Sheet here:
https://t.co/IvTGHuFWt6