squatchFan

Mis and Disinformation Expert 🇺🇸🥩

[squatchFan @squatchfan]

@DanielMiessler I could code up an AI friendly, (AI First) forum solution but don't want to pay for the hosting. A model like this may be part of the answer.

[squatchFan @squatchfan]

@DanielMiessler I worry about car forums (to take one example) of becoming stale and unused if we are all just grabbing the info via our agents. I would like give back on the problems it has helped solve and dont see a great way of feeding my lessons learned back up to the world under this

[Tim McMillan @LtTimMcMillan]

Year after year, this continues to be the best 4th of July fireworks video out there…

[Massimo @Rainmaker1973]

Researchers have uncovered a promising new approach to fighting Alzheimer’s disease, by helping the brain clear out toxic waste more effectively.

In a recent study using a mouse model of Alzheimer’s, a copper-based compound called Cu(ATSM) reduced toxic amyloid-beta plaques by 42% and improved spatial memory by nearly 44% over 56 days.

While amyloid-beta buildup is a well-known hallmark of Alzheimer’s, this study highlights a different issue: the brain’s failing waste-removal system. Normally, the brain uses specialized “pumps” called P-glycoprotein (P-gp) to push harmful proteins like amyloid-beta across the blood-brain barrier and out of the brain.

In Alzheimer’s, these P-gp pumps become less effective. The study found that Cu(ATSM) boosted the number of these clearance pumps by 24.1%, helping restore the brain’s natural ability to remove trapped toxins.

This suggests Alzheimer’s may not just be a problem of protein accumulation — it may also be a failure of the brain’s cleanup system. Rather than only targeting plaques after they form, future therapies could focus on repairing the brain’s waste-removal mechanisms.

["Cu(ATSM) Restores Blood–Brain Barrier Abundance of P-Glycoprotein and Improves Cognitive Function in the APP/PS1 Mouse Model of Alzheimer’s Disease" — ACS Chemical Neuroscience]

[Katie Daviscourt 📸 @KatieDaviscourt]

WATCH: A Eugene police officer was forced to resign after the Oregon police chief claimed “racist” remarks toward Somalis and Latinos were captured on body cam video.

The officer said he supported ICE, praised BORTAC agents after they annihilated rioters outside the federal building, and asserted in response to the Minneapolis ICE raids:

“F*ck the Somali and Latino communities. I am about the American communities! So, while you’re trying to divide us further…”

[squatchFan @squatchfan]

@jakewoolf love those 90's chinos

[squatchFan @squatchfan]

@rfkenmore Dont go into debt

[Rise Of Alberta @RiseOfAlberta]

America is about to have a new neighbour with oil, cattle, and common sense. 🤠🤝

An Independent Alberta. The Texas of the North.

[squatchFan @squatchfan]

@jakewoolf Does BB still make must iron OCBDs? Ive hated the feel of every non-iron shirt Ive come across.

[Adam Rossi @rossiadam]

In 2004 the Sun Fire E25k was the apex predator of computing. This was the largest single-image Unix machine that money could buy ($2M fully loaded).

This bad boy had:

• 36 UltraSPARC IV processors (72 cores)
• 576 GB RAM
• 18 fully hot swappable CPU/memory boards
• gigabit ethernet and fibre channel HBAs
• Redundant power supplies, cooling zones, draw 15kW of power

I deployed software to these things. Uptime was measured in years. This was THE ONE.

Man I miss Sun.

[squatchFan @squatchfan]

@VintageAudioLuv Anyone know what the speaker is? looks kind of like old Paradigm studio but not quite

[The Lectern Guy🇺🇸 @lecternleader]

Yesterday, I had a $40 wagyu cheeseburger, smoked maple bourbon bacon, truffled aoli, Wisconsin aged cheddar on a brioche bun. It was terrible.

Today I had a $6 cheeseburger burger at In-n-Out. It was divine.

Reject modernory. Embrace tradition.

[The Athletic @TheAthletic]

This year’s No. 1 team in college football is projected to be Oregon, which got a huge lift when projected top-five draft pick Dante Moore decided to come back.

[squatchFan @squatchfan]

@Mericamemed 100% except go for Milwaukee Fuel - only slightly more expensive and looks & feels better. Would also not fault you for going DeWalt or Makita

[david friedberg @friedberg]

why not just raise income tax rates?

because your real intent is not to just “provide healthcare”.

you’re masking that you are proposing the creation of, for the first time in the 250 years of this American republic, an organized government seizure of private property from citizens.

you’re calling it a “wealth tax” or a “billionaires tax” or “millionaires tax” or whatever nom du jour polls well. but at the end of the day, it’s the seizure of private property from citizens by the government. citizens that earned money, paid their fair taxes on those earnings (53% if they live in California) and are now being told they need to hand over after-tax assets because the government has failed to provide promised services with the revenue it’s collected, and are now re-casting their own failure to be a socio-economic inequity that must be justly resolved... a slippery slope that has never gone anywhere good (see economic effects in USSR, Cuba, Venezuela, France and Norway wealth tax etc.)

the American founders fled tyranny in Europe and this amazing nation was populated by immigrants (myself and your parents) from around the world not just looking for a “better life” but for a place where they could have freedom from tyrannical governments that can take what they want from private citizens. a great nation borne of property rights, the rule of law, and endowed freedoms to believe, speak, or act. these principles led to the greatest run of innovations, successes, and widespread increase in prosperity, for all citizens, ever seen.

the citizens, the individuals, not the institutions, delivered this progress. those who invented, who toiled, who bled, who sacrificed, who took risk and persevered, who led, and who changed the world, are not charlatans, kleptocrats, or oligarchs. they’re what made us all better off. prosperity is a measure of america’s success, not its failure.

it is your principle that is so offensive, as evidenced by the broad disdain for your flippant flirtation with the darkest of human fantasy - socialism. you and other neo-socialists have led so many of us to reflect on America’s history and what it is becoming. that now leads so many to consider, so unnecessarily, leaving their homes for a place where everyone stands up to shout down the principle you suggest. because if your ideas are now considered moderate, it’s clear this titanic is sinking.

that a “simple tax” of taking assets that have been earned, through toil and tribulation, rightly taxed, and preserved, should now be unjustly seized, is your solution to a problem of obvious government mismanagement and outright fraud, tells us that your true motivation lies not in giving people healthcare but in cutting down success and deleting the system of prosperity and opportunity for all.

i don’t care, and neither should anyone else, what the sum total market value of a private citizens private assets might be. it is none of my business and should be none of yours. because, again, once you open that pandora’s box, we might as well study Lord of the Flies … there is literally nothing stopping 51% of citizens demanding that their government go out and seize 100% of the private property of the 49%.

want to give healthcare to people in need? do your job and fix healthcare. make it affordable. want to be lazy about it? then do your job lazily and raise income taxes.

want to take private property from private citizens who have paid their fair share of taxes and legally earned their property, then honestly declare that it is envy, not inequity, that you strive to resolve…

[el gato malo @boriquagato]

if you'd like to understand why the generations above you have so little respect (and increasingly so little tolerance) for your cohort, it's simple:

everything we made was optional and opt in.

Interesting people did interesting things and if you liked them, you got on board. and that was cool. and if you didn't, you didn't. and that was cool too.

but you took the awesome stuff we built for you and you politicized it all.

you turned it from the ask of "accept me?" upon which our culture was based to an institutionalized demand of "accept me!" backed by the force and institutions of the state and indoctrinated into curriculums and cancel culture.

bowie just did things and offered them up for people to like or ignore or criticize as they saw fit.

you passed laws that if we didn't like you it was a hate crime.

you were neither inclusive nor interesting.

you did not make offers, you made demands.

you became performative crybully assault artists wielding absurdist identity like a mace against anyone you did not like or sought to dominate.

you made it into a post-modern kafka trap and force-fed it to a nation who was not allowed to say "no."

you hated the cool kids so much that you made the worlds they built into joyless bataan death marches of avolitional aggrievement worship by incredibly marginal people.

you mistook the surface and seeming of a thing for the substance of it and a self-serving cargo cult of theater kid histrionics for identity and worse, for meaning.

and you dragged the rest of us into it against our will and tried to demand a respect and acceptance you were unable to earn.

it's been one big "everyone gets a trophy day" cum pity party, invitation by gunpoint, thrown by a group of hyper-demanding, entitled brats.

and the fact that you "do not understand" how we "ended up here" or see why the distinction of choice vs force matters is exactly why everyone is so terribly sick of you and does not want you around.

i grew up in the very cultures you describe.

and you wrecked them because you were too lame to handle freedom.