3 amazing papers just out @Nature, the kind worth giving up sleep for🦉
Spatial multi-omics human maps:
-placenta: MIBI & DSP
-intestine: CODEX & snRNAseq & snATACseq
-kidney: Visium & scRNA & scATAC
After sequencing single cells, we are now finally putting them back together🧵
Today is International Day of Women and Girls In Science! To celebrate #WomenInScienceDay, we asked a few of our Broadies about the impact #WomenInScience make.
IL-23 signaling is required for baseline and IL-23-inducible IFN-γ immunity in both Vδ2+ γδT and MAIT cells @PhilippotQ @anne_puel@casanova_lab
Jacinta Bustamante @SciImmunology
https://t.co/WqysacN4Y4
1/6
📢And here it is: 😍
We are excited to announce the first international workshop on “Metabolism in the single cell era”.
It will be held in Bordeaux, France from the 20th to 22nd of September 2023
Amazing to see our Bone Marrow Organoid paper out today in the Feb issue of @CD_AACR@AbAttacks@beth_psaila
Even more exciting to see an amazing Spotlight article written about it! Thank you @marta_derecka and John Crispino 🤩 - I love it!
https://t.co/uwuqJqFQtL
One of the most impressive T cell papers in the past decades. A truly humbling experiment and incredibly important insights into T cell biology. @Masopust_Vezys truly amazing. A must read for all T cell biologist (all immunologists really). #instantclassic https://t.co/gfQvUYdrDD
Dysregulation of temporal metabolic adaptability is a key 🔑 feature of #immunosuppression.
Drs. Huiyang Yu, Nicolas Jacquelot, and Gabrielle Belz review how #metabolism regulates lymphocytes beyond the classical T cell subsets.
📂 https://t.co/Yo8N3Itlgy
During re-infection, primed CD103+ gut TRM cells turn on but don’t expand and CD103- gut TRM cells seed and renew CD103+ TRM cell populations in gut tissue, finds a new study in mice. @TU_Muenchen
📄: https://t.co/UEKkvcJxf7
#LiveForever! Nakanishi &co show @Nature that senescent cells are inflammatory & present an interferon signature, but are protected from T cell killing by up regulating PDL1, thus favoring inflammaging! Anti-PD1 decreases senescent cells in aged mice! https://t.co/GcEHIqO87D
The difference between doing a project and presenting it. An observation can lead to many avenues of explorations before focus turns to a specific discovery. Presenting it, in a talk / paper, follows inversely, with broad perspectives coming before & after the specific discovery.