stephen morrell

PhD @ UCL, deep learning, cancer detection and algorithmic trading. Love smart books

[stephen morrell @stephenmorrell5]

https://t.co/lk3NFkCyfn

Is this useful to anyone?

[stephen morrell @stephenmorrell5]

Open-sourced our Claude Code skill: port a CE Mark / UKCA technical file into an #FDA #510(k) for AI/ML #SaMD.

Includes the AI/ML deficiency pre-empt checklist FDA actually uses.

[stephen morrell @stephenmorrell5]

@afshineemrani @grok what degree is this supported in the current literature and what are implications for testing and prevention in middle age?

[stephen morrell @stephenmorrell5]

Ken Griffin called AI "all garbage" at Davos in January.

Four months later, he went home "fairly depressed" after watching AI agents at Citadel do work that used to take teams of PhDs monthsto complete. Done in days.

His words: "These are not mid-tier white collar jobs. These are extraordinarily high skilled jobs being automated."

That is the fastest skeptic-to-convert arc by anyone running real money on Wall Street.

I've been using agentic AI daily for CEO work at Elaitra for over a year now, and AI for 10y. Here's what Griffin is discovering that most leaders still haven't grasped:

The productivity boost is real (about 3x for me), but that's not even the main story.

It gives you new powers you simply didn't have before:
- Instant awareness across your entire operation
- Strategy that draws on more context than any human could hold in their head
- Better results, not just faster results
- Tools to do anything you do on your computer (let that sink in…)

Griffin's PhD teams weren't slow. They were limited by being human. That's the part that made him depressed.

For me it's the opposite. As a CEO of a small company, AI gave me capabilities I could never have afforded to hire. It's the greatequaliser for founder-led businesses.

If you're a leader who's curious about what this actually looks like in practice (not the demo, the daily reality), it's genuinely myfavourite thing to talk about. I’m curious what’s holding others back. DM me or grab a coffee.

[stephen morrell @stephenmorrell5]

@elonmusk Agentic workflow is doing this for us already here. It’s my current favourite conversation topic!

[stephen morrell @stephenmorrell5]

@Mnilax Made a Kindle-ready transcript of this interview (Lenny's Podcast x Boris Cherny). Cleaned up, 26 section headers, clickable TOC.
EPUB download: https://t.co/FGUKWVP97a
Built with an open-source Claude Code skill:
https://t.co/jlSuKWMpZy

[Max @minordissent]

Elon’s great super power is weapons grade autism combined with 99.9th percentile conscientiousness. Most people that conscientious are risk averse rule followers and most people that autistic have non existent executive function such they just become anti semitic mentats incapable of building anything.

[stephen morrell @stephenmorrell5]

@GergelyOrosz only applies to public repos... Private repos
are not used for Copilot training.

[Obie Fernandez @obie]

https://t.co/kQfCcoPMDv

[Tyler Mullins @Tyler_omni]

@milesdeutscher guys, be careful downloading random skills. they can be full of malicious intent. DYOR

[stephen morrell @stephenmorrell5]

Yup

[Andrew Wilkinson @awilkinson]

I underestimated how emotional the impact of AI would be.

For a decade, I was depressed about work.

The best part of business is manifesting an idea.

Seeing a problem, then fixing it for yourself and others.

The worst part of business is trying to herd cats.

Motivating the dozens of people required to execute on a vision.

I didn’t fully realize this until I started using Claude Code, but I was borderline depressed when it came to work.

I’ve always been frustrated by the gap between vision and execution. I’ve never been good at managing large groups of people.

I’d have an idea I was excited about, but the moment it exceeded my own skillset (coding, for example), I had to hand it off to others.

Wonderful team members—but with their own ideas. Their own pace. Their own taste.

And often, after months of meetings and false starts, we’d end up with something I didn’t love, or felt frustrated by.

I found this process so draining that I eventually gave up.

I delegated almost all operations to CEOs.

From a business standpoint, this worked out great.
But my original love—building things, with my hands on the tools—was lost for almost a decade.

Claude Code has brought back my fire.
It feels like I have 50 (nearly) free super-genius employees living in my terminal.

If I wake up in the middle of the night, there’s a 50% chance I say “fuck it” and go downstairs to mainline Claude Code at 4 a.m.

There’s no longer a gap between vision and execution. It feels like: if you can imagine it, you can build it.

Sure, there are frustrating bugs. It can get you 95% of the way there—and the final 5% can take an astonishingly long time.

But it feels like magic. I genuinely can’t believe this technology exists.

In the last month alone, I’ve used it to:

Adapt 10 hours of interviews with my father into a beautifully written memoir

Build a personality analysis tool for individuals and couples to explore mental health and relationship dynamics (coming soon)

• Design an astonishingly beautiful website for a vacation rental I own

• Create a bot that helps manage and execute all my Things tasks (including drafting emails and doing research)

• Optimize my home Wi-Fi network

• Build a deal analysis tool to deep-dive potential acquisitions and write investment memos

• Create an automated personal journal that captures notable moments from my day (things my kids said, decisions I made, meeting notes, etc.)

And an endless number of random tasks—easily a year or more of human work.

The craziest part: I’ve only spent a few thousand dollars on Claude credits.

Those of us using this are probably still 0.0001% of the population.

I can’t even imagine what gets built once this is widely distributed—especially when it takes physical form through robotics.

The next two years are going to be mental.

This makes the printing press look like a joke.

[Andrew Wilkinson @awilkinson]

I underestimated how emotional the impact of AI would be.

For a decade, I was depressed about work.

The best part of business is manifesting an idea.

Seeing a problem, then fixing it for yourself and others.

The worst part of business is trying to herd cats.

Motivating the dozens of people required to execute on a vision.

I didn’t fully realize this until I started using Claude Code, but I was borderline depressed when it came to work.

I’ve always been frustrated by the gap between vision and execution. I’ve never been good at managing large groups of people.

I’d have an idea I was excited about, but the moment it exceeded my own skillset (coding, for example), I had to hand it off to others.

Wonderful team members—but with their own ideas. Their own pace. Their own taste.

And often, after months of meetings and false starts, we’d end up with something I didn’t love, or felt frustrated by.

I found this process so draining that I eventually gave up.

I delegated almost all operations to CEOs.

From a business standpoint, this worked out great.
But my original love—building things, with my hands on the tools—was lost for almost a decade.

Claude Code has brought back my fire.
It feels like I have 50 (nearly) free super-genius employees living in my terminal.

If I wake up in the middle of the night, there’s a 50% chance I say “fuck it” and go downstairs to mainline Claude Code at 4 a.m.

There’s no longer a gap between vision and execution. It feels like: if you can imagine it, you can build it.

Sure, there are frustrating bugs. It can get you 95% of the way there—and the final 5% can take an astonishingly long time.

But it feels like magic. I genuinely can’t believe this technology exists.

In the last month alone, I’ve used it to:

Adapt 10 hours of interviews with my father into a beautifully written memoir

Build a personality analysis tool for individuals and couples to explore mental health and relationship dynamics (coming soon)

• Design an astonishingly beautiful website for a vacation rental I own

• Create a bot that helps manage and execute all my Things tasks (including drafting emails and doing research)

• Optimize my home Wi-Fi network

• Build a deal analysis tool to deep-dive potential acquisitions and write investment memos

• Create an automated personal journal that captures notable moments from my day (things my kids said, decisions I made, meeting notes, etc.)

And an endless number of random tasks—easily a year or more of human work.

The craziest part: I’ve only spent a few thousand dollars on Claude credits.

Those of us using this are probably still 0.0001% of the population.

I can’t even imagine what gets built once this is widely distributed—especially when it takes physical form through robotics.

The next two years are going to be mental.

This makes the printing press look like a joke.

[stephen morrell @stephenmorrell5]

https://t.co/4eOMYJiEto

[stephen morrell @stephenmorrell5]

Just open-sourced my @ClaudeCode skills - fast Apple Notes→markdown export, Gmail drafting, Google Sheets/Calendar/board reporting. Thx @bcherny Looking for alpha users 🧪

Link below 👇

[stephen morrell @stephenmorrell5]

@businessbarista Claude

[stephen morrell @stephenmorrell5]

I love Claude Code. 🫶😎 It saved 95% of my Google cloud costs by installing the CLI etc and being my GC engineer. 🤓

Google’s Gemini and the dashboard failed miserably. 😖

Thanks @bcherny !!

[Charly Wargnier @DataChaz]

A must-bookmark for vibe-coders.

@YCombinator’s guide to making the most of vibe coding:

[Pedro Domingos @pmddomingos]

Hinton is no longer afraid of superintelligence.

[stephen morrell @stephenmorrell5]

@karpathy Dreams = concept distillation. REM replays what matters, keeps the gist, dumps the fluff. LLMs need a similar “sleep” phase: tag salient episodes, replay, distill into skills—so they wake with better ideas, not just more tokens. #AI #neuroscience

[stephen morrell @stephenmorrell5]

@dwarkesh_sp @karpathy Karpathy’s interview as an essay for optimal ingestion. https://t.co/QvqTVhC0j9