I'm creating 3D tours of open single cell RNA-seq data in UMAP space. Here, using data from 50k brain cells by the @AllenInstitute . (https://t.co/aOSpYfve70). The UMAP position and class of every cell is read into Blender, realized as a stylized, class-specific model I sculpted
Had fun working on this project characterizing the mechanical behavior of latrophilin-3 (Lphn3), a cell adhesion molecule that is important for excitatory synapse formation in the brain! Tweetorial below (1/5)
Code to determine colocalization and transformations are available here with demo data: https://t.co/IbJwV7GKPk. Full Data available to public: https://t.co/5dwRXZkZk8
Check our new paper @NatureComms - We demonstrate a novel Single-Molecule Colocalization Assay (SiMCA) to eliminate background produced by non-specific binding. Great collaboration with @Dunn_Lab , co-lead by @AmaniHariri20@SharonNewman0@steventan17 https://t.co/GmqWuXT52I
Finally OUT!! 🥳Check our new paper “Improved immunoassay sensitivity and specificity using single-molecule colocalization”@NatureComms SiMCA uses the power of Single Molecule Fluorescence in sandwich-type bioassays #ScienceTwitter#fluorescence#SMFM#ELISA#SiMCArdWhynot ⬇️🔬🚦
Illustration I created for @A_Amunts as a stylized interpretation of his group's new findings in @Nature on the assembly of the mitoribosome. We eventually brought this illustration to life in the animation below. Paper link: https://t.co/X3piu4qK2m
How do cadherin-catenin complexes interact cooperatively with F-actin to assemble into large, organized clusters observed in cells? Our new pre-print may provide some insight. Big shoutout to my co-first author @bax1337 for working with me on this! https://t.co/loAaHnuFCI [1/3]
Short animation I made from one of my previous scientific illustrations: A little macrophage, getting ready to perform some phagocytosis and enjoy a picnic feast of bacteria and viruses. #SciArt#Blender3d
I'm working on bringing some of my previous scientific illustrations to life as animations. Short animation stylizing the idea of CAR T-cell therapy; here, engineered T-cells conducting surveillance, searching for cancer cells to destroy. #sciart#Blender3d
I created this illustration for @ljiresearch for an article describing research at LJI on the role of mucosa in immunity (https://t.co/rZgLQUA5sj). The idea was to represent epithelia and epithelia-associated T-cells as a first line of defense against invading pathogens. #SciArt
HOW do cells respond to being peeled off e.g. when you pinch yourself too hard? We find that once cells partly detach, newly extruded membrane tethers attached to the surface (e.g. retraction fibers) guide cells back to their original location https://t.co/uZYTS39qr0 1/
How do hundreds of species coexist in rainforests or your gut without driving each other extinct? Our new work shows how correlations among interspecies interactions, e.g. the enemy of my enemy is my friend, may help maintain the diversity of ecosystems https://t.co/F3kmRZGZUi 🧵
It’s official now! Super excited to announce that I’ll be starting my Lab @UBC@UBCChem in 2023! If you’re interested in doing great interdisciplinary research in Canada BC 🇨🇦🇨🇦, please DM me!!🤩✨
I like exploring creative ways to illustrate scientific ideas. This is an illustration I created to represent the idea of mechanotransduction: a process in which cells sense the mechanics of their environment.
"Macrophage picnic." An illustration I created to represent the idea of a macrophage. Macrophages are cells in the immune system that consume foreign organisms, such as bacteria and viruses, through a process known as phagocytosis. #SciArt