Sharon S. Newman

PhD student @Stanford @HTSohLab | Motivated by accessible healthcare and education | Excited about biosensing, diagnostics, and algorithms | Outdoor enthusiast

[Sharon S. Newman @SharonNewman0]

nor require differential panels or dilutions! This tuning strategy with PLA highlights the opportunity to achieve sensitive, accurate quantification of diverse analytes in a highly multiplexed fashion. We're excited to see where this tuning is taken for better health monitoring!

[Sharon S. Newman @SharonNewman0]

New paper w/ @HTSohLab! This is a large part of my PhD, Im excited to share some of those results!
In this work, we provide a strategy to overcome the problem of measuring proteins that span >7 orders of magnitude using only 5ul of serum. How? 1/4🧵

[Nature Communications @NatureComms]

.@SharonNewman0 and colleagues report the ‘EVROS’ equalisation strategy as a method for quantifying protein biomarkers with a dynamic range spanning seven orders of magnitude @HTSohLab Institute @Stanford #proximityligationassay
#BiotechNatureComms

https://t.co/SLnbu0aJjw

[Sharon S. Newman @SharonNewman0]

We propose a tuning approach for proximity-based assays, enabling simultaneous quantification of four analytes across from low fM to mid-nM. Importantly, this solution does not require modification of the intrinsic affinity of affinity reagents to their targets... 3/4

[Fabian Theis @fabian_theis]

Lovely @xkcdComic on K-means clustering.

[Sharon S. Newman @SharonNewman0]

Who’s at or coming to the #MNMC conference? The @HTSohLab and I are excited for #biosensors convos and ways to convert #bench2bedside. Also for views in Hawaii!!

[Sharon S. Newman @SharonNewman0]

support or adaptive technologies, please consider this auction, volunteering, or spreading the word!
Org: https://t.co/T5myOxgzMn
Auction: https://t.co/qAaxb4ip03
#adaptiveathlete #silentauction #casinoroyale #skiing #accessibilityforall #cycling #rideyourbike #ridebikes (4/4)

[Sharon S. Newman @SharonNewman0]

This is my mom! Thanks to OutdoorsForAll, my mom has had the best year of her life, and given her new outlooks for what she can do. She's skied, road and mountain biked all for the first time this year! Now, she goes biking for a few miles practically everyday, and can (1/4)

[Sharon S. Newman @SharonNewman0]

only heard through people all her life -- And this only thanks through the countless volunteers and organization of Outdoorsforall that make this possible.

Outdoorsforall is having a silent auction, if you want to support providing the outdoors to those that need more (3/4)

[Long Lab @longlabstanford]

The champagne!! ⁦@NobelPrize⁩ ⁦@CarolynBertozzi⁩ ⁦@Stanford_ChEMH⁩ ⁦@Stanford⁩

[Sharon S. Newman @SharonNewman0]

California needs more rain for many reasons. This is another reason.

[The Soh Lab @ Stanford @HTSohLab]

Our paper “Improved immunoassay sensitivity and specificity using single-molecule colocalization” https://t.co/GmqWuXT52I is now featured on the Editors’ Highlights webpage in the “Biotechnology and methods” research section @NatureComms #Biotechnology https://t.co/5llWodZQFr

[Sharon S. Newman @SharonNewman0]

Have to really thank co authors @AmaniHariri20 , @steventan17 and our lovely collaboration with @Dunn_Lab. Y’all have helped me learn a lot in the process and I’m so glad to have had the chance to get this idea out together! Thanks for making this fun to tackle together!

[Sharon S. Newman @SharonNewman0]

Check out recent work from my phd with co authors @AmaniHariri20 and @steventan17 out in @NatureComms working towards minimizing background signal that plague immunoassays by using fluorescent colocalization and image processing methods!

[The Soh Lab @ Stanford @HTSohLab]

Check our new paper @NatureComms - We demonstrate a novel Single-Molecule Colocalization Assay (SiMCA) to eliminate background produced by non-specific binding. Great collaboration with @Dunn_Lab , co-lead by @AmaniHariri20 @SharonNewman0 @steventan17 https://t.co/GmqWuXT52I

[Sharon S. Newman @SharonNewman0]

Code to determine colocalization and transformations are available here with demo data: https://t.co/IbJwV7GKPk. Full Data available to public: https://t.co/5dwRXZkZk8

[Sharon S. Newman @SharonNewman0]

A lot of my phd focuses on solving fundamental limitations in assay design via #modeling, #assay molecular manipulation and #computational tools. This one is a nice synergy between these three.

[Sharon S. Newman @SharonNewman0]

@kaiyufu90 @NotreDame @BohnGroup @NDscience @HTSohLab @StanfordEng @StanfordMed @FuLabND We'll miss having you Kaiyu!! Your future students will be lucky to have you as their advisor. They will become fantastic thinkers by being able to work with you.