Diastereoselective Synthesis of Difluoromethylene—Bridged Cyclopropane-Cyclobutanes from 2-(Difluoromethylene)-cyclobutyl Sulfonium Salt and Cyclopropenes
https://t.co/bCF5nuXaLQ
🦋1-Azabicyclo[1.1.0]butanes emerge as “spring-loaded” synthons for azetidine construction, where strain-release drives modular ring opening, skeletal editing & rapid access to sp³-rich N-heterocycles ⚡🔺
@ChemEurJ@Luisi_Lab
https://t.co/8aGDDk7Yx1
Great to see our recent @J_A_C_S paper about the synthesis of 4-members rings from alkenes https://t.co/Qp7Evqu53c highlighted as Synfacts of the Month https://t.co/d2ZCul3ZED thanks @thiemechemistry for the recognition and well done to the team!
🔺Parallel kinetic resolution of highly strained aziridines enables enantioenriched chiral alcohols via divergent pathways—transforming ring strain into stereochemical elegance and synthetic power ⚡️
@ACSCatalysis
https://t.co/ui89suJIWJ
⚡️ Strain sculpted into function: Enantioselective access to rigid bicyclo[2.1.1]hexanes transforms highly strained frameworks into meta-benzene bioisosteres—unlocking 3D chemical space with precision and elegance
@NatureSynthesis@TortosaLab
https://t.co/Fdb7tfqWQq