Out now in @CD_AACR – our analysis of BRCA reversion mutations in PARPi/platinum-resistant cancer! https://t.co/cNb2QkJg8O and data: https://t.co/I41HW1bKGH
Just taking a moment to appreciate this honey locust tree in the grounds of the school next to my flat, looking lovely in its autumn colours despite the grey skies. @LBHF are deciding today whether to replace all the trees and playgrounds surrounding this school with flats.
Updated https://t.co/I41HW1bKGH to include lots of new cases, including from our recent paper (https://t.co/AxhADKLR6Z). Now includes 759 reversions from 382 patients. Big thanks to @LorenaMagraner and @RachelAlcraft for annotations & maintenance @ICR_London@BreastCancerNow!
Our latest on resistance to PARPi and platinum in BRCAm breast cancer - lots of reversions as well as a possible role for reversions effected via splicing changes - more in Maya's thread below!
What are the mechanisms of resistance to PARPi in advanced BRCA1/2 mutated #breastcancer patients? Proud to have co-led this study with the dream team @ICR_London with Prof.A. Tutt, @IcrLordLab @stveep
Check out our findings at @Annals_Oncology 🧵 (1/5) https://t.co/XTOrGLd0dy
Very tired legs all round by now at #AACR23 but save some energy to come see our poster tomorrow morning for our latest on PARPi resistance in TNBC! @ICR_London @IcrLordLab @GuardantHealth
📣THIS TIME NEXT WEEK📣
We are so excited to be back playing @magic_pub we have even got some new music
If you have no plans for Saturday 25th, you do now 🕺🪩Book your tickets now to see us play @magic_pub. Link is in our bio!
#livemusic#livemusiclondon#london#londonlive
Leaving the warm studio for the cold streets again this weekend...though we will let our drummer out from behind the wall! Catch us BUSCing on Sunday at Chiswick Flower Market at 1pm and 2pm! @ChiswickFlowers
📢Upcoming event news!
@ICR_London 's Esther Artwert, @erik_wennerberg and @stveep will be introducing their #immunooncology projects to possible industry partners next Tuesday in the latest in @IN_PART 's online Global Challenges series.
Sign up here! https://t.co/Ton5wUg14I
I am beyond excited to share with you that I am part of founding the company VUS Diagnostics. Our mission is to help bring personalised treatment approaches to patients by designing cell based functional assays that addresses the mechanism underlying the drug response.
We have an open postdoctoral research position to study DNA repair pathway choice in BRCA1-mutated cancers. Interested in studying this process to find new therapies for these cancers? Please apply here 👉 https://t.co/ygvWQi80MF
When I moved flat I thought being opposite a school might be a bit noisy...well, the kids are fine - it's drivers that are the problem, especially today. Constant selfish honking, terrible music, road rage, car alarms (omg), even someone knocked off a moped...
A great opportunity to join us in a senior lab-based role at ICR, studying the DNA damage response in Breast Cancer with Prof. Andrew Tutt. Work on the next generation of treatments in a team of scientists, clinicians and patients! #ScienceJobs https://t.co/8JrLjwWbqU
If you don't think you match these roles exactly, feel free to DM or email me anyway for future opportunities - we're always looking to work with smart, creative people who share our research interests, and can work with you to develop ideas for fellowships #postdocjobs#postdoc
We're hiring for postdoc and technician roles - come and be part of the next chapter of research into PARPi resistance and new targets for triple negative breast cancer working with the Lord and Tutt groups at @ICR_London. https://t.co/LnCPFikiIO