Spliceman42

[Spliceman42 @Sunhillow42]

Our paper is out describing discovery of a potential novel small molecule therapeutic for the treatment of Huntington’s Disease https://t.co/Iw0nr9hPli

[Spliceman42 @Sunhillow42]

@YongshengShi Great meeting Yonsheng.

[Spliceman42 @Sunhillow42]

@KonaBigWave Sadly I won’t waste your guess. I just finished the last one in my fridge so none now :(

[Olivier George @brainaddiction]

It's clear that many do not understand what @NIH-funded research does to improve health. It's time to revive a study published 10 years ago that provides incredible information about this. link in the comment

Every single new drug approved by the FDA from 2010–2016 was built on NIH-funded research—that’s all 210 drugs. But what the public sees is just the tip of the iceberg.

Pharma takes credit for the final product, but beneath each drug developed, there are ~20 years of basic research, and 90% of the cost is from basic research funded by the NIH, which discovers drug targets, understands disease mechanisms, and creates life-saving treatments.

Figuring out how cancer evades the immune system, how addiction rewires the brain, and how heart disease develops is the role of the NIH, creating the foundation for the breakthrough drugs that come 20 years later, and the NIH does all that with only 0.8% of the US budget.

Without NIH, there would be no cancer immunotherapy, no anti-overdose medication, no anti-heart attack or stroke medication, no cutting-edge treatments.

If NIH funding is cut, the iceberg will melt. That means fewer cures, more suffering, and more lives lost.

The science beneath the surface keeps us afloat.
Invest in NIH. Invest in life

[Spliceman42 @Sunhillow42]

@Cathrinmachin It looks like chromosomes separating

[PTC Therapeutics @PTCBio]

#BreakingNews: Today, we are proud to announce that the FDA has approved our #genetherapy for treating adults and children with #AADCdeficiency. Learn more: https://t.co/6QShxigmdt

[Spliceman42 @Sunhillow42]

@UWMadisonRNA @woodson_lab I saw it too. Go @woodson_lab !

[Brenton Graveley @graveley]

@SamuelEButcher @UWMadisonRNA Nice Sam!

[Spliceman42 @Sunhillow42]

@UWMadisonRNA No U1

[Nasdaq Exchange @NasdaqExchange]

🔬 @PTCBio is translating science to transform lives for patients.

$PTCT is a science-driven, patient-centered biopharmaceutical company focused on discovering best-in-class treatments & commercializing medicine for patients with rare disease. #NasdaqListed

[Gjenni Voss @gjendinevoss]

Did you know that the majority of transcripts in a squid neuron are a recoded by A-to-I RNA editing? 🦑🧠🧬 Are you curious WHY and HOW? I can tell you - but you'll have to come to poster 433 tonight to find out! #RNA23
@jrRNAscientists @RNASociety #RNA2023

[Spliceman42 @Sunhillow42]

@Cassandra_Hayne @RobinStanleyLab @danielsmundo @Gagamboy18 @mjborgnia Cool

[Spliceman42 @Sunhillow42]

CTP celebrates PTCs 25 years of cutting edge science with this original tune

https://t.co/lf6aR4EYBx

[Al Hughes Dukes @Alsboringtweets]

Cool Games, the Christmas edition. Here you go @JerryRecco

[Spliceman42 @Sunhillow42]

@MUPfeif I think they are drumsticks not wings

[Dr. Cassandra Hayne @Cassandra_Hayne]

Excited to share our structure of the human trna splicing endonuclease complex bound to an intron containing pre-tRNA!
@RobinStanleyLab

[Spliceman42 @Sunhillow42]

@jmcoller @GraveleyLab @yeo_lab Cool Brent!

[Spliceman42 @Sunhillow42]

@JeanBeggs1 Hearing this news makes me remember all the amazing interactions I have had with Christine throughout the last 25 years. She was an amazing mentor to an entire field of scientists and taught so many about the awesome power of yeast genetics and so much more. My heart misses her

[Spliceman42 @Sunhillow42]

@Cassandra_Hayne @lapassmore @acorbe2 @ArraianoLab Great data.

[Dr. Cassandra Hayne @Cassandra_Hayne]

Huge thanks to the organizers for organizing a great meeting!
@lapassmore @acorbe2 @ArraianoLab #PCGE22

[Shayna @shaynagoldman_]

Panarin to Copp to Strome who has quiiiite a bit of space there...