Thanks to @NBCNews for the chance to discuss Mayor Mamdani's comments & the broader significance of an ICC arrest warrant for Israeli Prime Minister Netanyahu on charges of the war crime of starvation and crimes against humanity including murder.
In a new Science study, researchers report an unexpected role for sensory nerves in bone healing, providing insights into communication between the nervous system and the cells responsible for bone repair.
Learn more in a new #SciencePerspective: https://t.co/7fUwqLKh98
Today, we are sharing interim clinical data from our ongoing Phase 1/2 studies in the POLARIS program evaluating ETX101, a potential one-time gene therapy, in children with SCN1A+ Dravet syndrome. The oral presentation at #AES2025 highlights a favorable safety and tolerability profile, sustained seizure reduction, and meaningful and progressive neurodevelopmental gains, particularly in cognitive skills essential for communication, learning, and independence. The data will be featured again tomorrow in a poster presentation.
Read the full press release here: https://t.co/w7w9btPAq6
Presentation Details
POLARIS Phase 1/2 Program Interim Safety and Preliminary Efficacy Results of ETX101, a One-Time Gene Regulation Therapy, in Young Children with Dravet Syndrome” will be presented by Joseph Sullivan, M.D., University of California, San Francisco, and Principal Investigator on the ENDEAVOR study.
→ Oral Session: Platform session B.02
→ Date & Time: Friday, December 5, 2025, 12:45-1:00 pm ET
→ Location: Georgia World Congress Center Room B313
→ Poster Session: Poster #1.308
→ Date & Time: Saturday, December 6, 2025
→ 12:00-6:00 pm ET (Poster displayed);
→ 12:00-2:00 pm ET (Author present)
→ Location: Georgia World Congress Center Exhibit Hall B2
#Dravetsyndrome #genetherapy
BREAKTHROUGH: I have invented a novel object notation format that provides an additional 71% token savings over JSON and 59% over TOON.
I have named it VSC (Values Separated by Comma), patent pending.
"I particularly enjoyed being immersed in the ethos of engineering, which is very different from the ethos of science. A good scientist is a person with original ideas. A good engineer is a person who makes a design that works with as few original ideas as possible. There are no prima donnas in engineering."
Freeman Dyson
https://t.co/PQwp0RoJBI
@bluebirdpoopies@TrueFactsStated@DOGE It’s exactly what they have been doing in all their ill-conceived federal cuts. Cut, cut, cut, ooops, backtrack. With every one involved in the cutting being an absolute proud moron.
Holy shit. Instead of admitting they were wrong, @DOGE literally changed FPDS data to try to cover their asses. The website now says $8B but you can easily verify that the real number is $8M by cross-referencing with any other source as noted below.
Yesterday on TNL I elaborated on my back and forth with @stephenfhayes. It was a long discussion, but here’s the core point: It’s about providing accurate analysis and an honest threat assessment for our audiences. Which, even if you think Harris is bad, there’s no world in which she’s worse than Trump:
I keep hearing stories about these median humans with a plan for their life, but everyone I meet is just like how the fuck did I get here.
Giving comfort to young people is sometimes saying nobody can promise you anything, you're not used to that, but you'll grow into living it.
My fellow Democrats, I have decided not to accept the nomination and to focus all my energies on my duties as President for the remainder of my term. My very first decision as the party nominee in 2020 was to pick Kamala Harris as my Vice President. And it’s been the best decision I’ve made. Today I want to offer my full support and endorsement for Kamala to be the nominee of our party this year. Democrats — it’s time to come together and beat Trump. Let’s do this.